Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lorraine L. Marnell"'
Autor:
Carolyn Mold, Kristopher D. Marjon, Terry W. Du Clos, Lorraine L. Marnell, Jinghua Lu, Peter D. Sun
Publikováno v:
Protein Science. 23:378-386
The pentraxins, C-reactive protein (CRP), and serum amyloid P component (SAP) have previously been shown to function as innate opsonins through interactions with Fcγ receptors. The molecular details of these interactions were elucidated by the cryst
Autor:
Peter D. Sun, Ruipeng Wang, Lorraine L. Marnell, Jinghua Lu, Terry W. Du Clos, Kristopher D. Marjon, Carolyn Mold
Publikováno v:
Proceedings of the National Academy of Sciences. 108:4974-4979
C-reactive protein (CRP) is an important biomarker for inflammatory diseases. However, its role in inflammation beyond complement-mediated pathogen clearance remains poorly defined. We identified the major IgA receptor, FcαRI, as a ligand for pentra
Publikováno v:
The Journal of Immunology. 182:1397-1403
C-reactive protein (CRP) is an acute-phase protein with therapeutic activity in mouse models of systemic lupus erythematosus and other inflammatory and autoimmune diseases. To determine the mechanism by which CRP suppresses immune complex disease, an
Autor:
Kristopher D. Marjon, Carolyn Mold, Lorraine L. Marnell, Peter D. Sun, Jinghua Lu, Terry W. Du Clos
Publikováno v:
Nature
The classical pentraxins, serum amyloid P component (SAP) and C-reactive protein (CRP), are major acute phase reactants in mouse and man. As shown in this paper, pentraxins recognize various FcγRs, and SAP opsonization activates FcγR-mediated phago
Autor:
Kevin T. Du Clos, Mary-Pat Stein, Lorraine L. Marnell, Terry W. Du Clos, Carolyn Mold, Ranhy Bang, Corinn Chivington-Buck
Publikováno v:
Journal of Biological Chemistry. 280:25095-25102
Human C-reactive protein (CRP) is a classical, acute phase serum protein synthesized by the liver in response to infection, inflammation, or trauma. CRP binds to microbial antigens and damaged cells, opsonizes particles for phagocytosis and regulates
Publikováno v:
Molecular Immunology. 30:701-708
C-reactive protein (CRP) binds to chromatin, histones, and small nuclear ribonucleoproteins (snRNPs) through a phosphocholine (PC)-inhibitable, calcium-dependent binding site. snRNPs process pre-mRNA to mature mRNA and are composed of small uridine-r
Publikováno v:
Thrombosis Research. 63:569-575
Autor:
Yolanda Jaramillo, Lorraine L. Marnell, Robert P. Searles, Susan M. Savage, Wilmer L. Sibbitt
Publikováno v:
Clinical Immunology and Immunopathology. 55:263-272
Sera and synovial fluid (SF) from rheumatoid arthritis (RA) patients were evaluated for anti-HLA class II β-chain antibodies using single and two-dimensional immunoblots. The antibodies from RA sera and SFs which reacted with class II β-chain deter
Autor:
Wilfredo Rodriguez, Julie A. Hutt, Lorraine L. Marnell, Carolyn Mold, J. Sjef Verbeek, Terry W. Du Clos, Milena Kataranovski
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 178(1)
C-reactive protein (CRP) is a member of the pentraxin family of proteins and an acute phase reactant. CRP modulates the response to inflammatory stimuli including LPS and C5a. We recently demonstrated that CRP prevents and reverses proteinuria in acc
Autor:
Carolyn Mold, Lorraine L. Marnell, Dao Tran, Julie A. Hutt, Wilfredo Rodriguez, Terry W. Du Clos, Gregg J. Silverman
Publikováno v:
Arthritis and rheumatism. 54(1)
Objective C-reactive protein (CRP) is an acute-phase serum protein with binding reactivity to nuclear autoantigens and immunomodulatory function. The MRL/lpr mouse is an important model of human systemic lupus erythematosus (SLE). These mice develop