Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lorraine Barber"'
Autor:
Chris Abell, Kalina T. Haas, Matthias T. Ehebauer, Luca Pellegrini, Amy Emery, May Marsh, David J. Huggins, Chiara R. Valenzano, Tom L. Blundell, Ashok R. Venkitaraman, Bryn Hardwick, Miyoung Lee, Lorraine Barber, Timothy Sharpe, Rajavel Srinivasan, John Skidmore, Nicola J. Francis-Newton, Alessandro Esposito, Duncan Scott, Claudio Dagostin, Marko Hyvönen, Gerhard Fischer, Andrew R. Bayly, Grahame J. McKenzie, Trevor Perrior, Tommaso Moschetti, Anthony G. Coyne
Publikováno v:
Cell Chemical Biology
'Cell Chemical Biology ', vol: 28, pages: 835-847 (2021)
'Cell Chemical Biology ', vol: 28, pages: 835-847 (2021)
Summary BRCA2 controls RAD51 recombinase during homologous DNA recombination (HDR) through eight evolutionarily conserved BRC repeats, which individually engage RAD51 via the motif Phe-x-x-Ala. Using structure-guided molecular design, templated on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e8b51ead91fb6e0441f1e51a013c4f
Autor:
Gerhard Fischer, Matthias T. Ehebauer, Luca Pellegrini, Marko Hyvönen, David J. Huggins, Chiara R. Valenzano, Ashok R. Venkitaraman, Rajavel Srinivasan, Timothy Sharpe, Anthony G. Coyne, Alessandro Esposito, Duncan Scott, Tommaso Moschetti, Kalina T. Haas, Chris Abell, May Marsh, John Skidmore, Andrew R. Bayly, Grahame J. McKenzie, Lorraine Barber, Trevor Perrior, Tom L. Blundell, Nicola J. Francis-Newton
SUMMARYBRCA2 controls RAD51 recombinase during homologous DNA recombination (HDR) through eight evolutionarily-conserved BRC repeats, which individually engage RAD51 via the motif Phe-x-x-Ala. Using structure-guided molecular design, templated on a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c1c19577aace398628cc240fb87a89
https://doi.org/10.1101/2020.07.15.200709
https://doi.org/10.1101/2020.07.15.200709
Autor:
Ashok R. Venkitaraman, Kenneth P. Olive, Jon G. Jonasson, Michael Lim, Florian A. Karreth, Venkat Pisupati, Liam D. Cassidy, Ferdinandos Skoulidis, Jorunn E. Eyfjord, Hordur Bjarnason, Susan A. Clatworthy, Susan E. Davies, David A. Tuveson, Lorraine Barber
Publikováno v:
Cancer Cell. 18(5):499-509
Summary Inherited heterozygous BRCA2 mutations predispose carriers to tissue-specific cancers, but somatic deletion of the wild-type allele is considered essential for carcinogenesis. We find in a murine model of familial pancreatic cancer that germl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5ca09c04615931e734b189f99727c7
Autor:
Alison M. Smith, Cathie Martin, Lorraine Barber, Trevor L. Wang, Nicholas J. Kruger, D. H. Paul Barratt
Publikováno v:
Plant Physiology. 127:655-664
Genes encoding three isoforms of sucrose synthase (Sus1, Sus2, and Sus3) have been cloned from pea (Pisum sativum). The genes have distinct patterns of expression in different organs of the plant, and during organ development. Studies of the isoforms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2fe1df52ab3c672422c7f982d8c1d6
https://doi.org/10.1104/pp.010297
https://doi.org/10.1104/pp.010297
Autor:
James R. Lloyd, Alison M. Smith, Josephine Craig, Anne Edwards, Trevor L. Wang, Cliff L. Hedley, Cathie Martin, Lorraine Barber, Kim Tomlinson
Publikováno v:
The Plant Cell. 10:413-426
Mutations at the rug5 (rugosus5) locus have been used to elucidate the role of the major soluble isoform of starch synthase II (SSII) in amylopectin synthesis in the developing pea embryo. The SSII gene maps to the rug5 locus, and the gene in one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351ea46ee7abfd6696b5c865d673597b
https://doi.org/10.1105/tpc.10.3.413
https://doi.org/10.1105/tpc.10.3.413
Autor:
Paul Barratt, Linda L. Handley, Christopher D. Gardner, Cliff L. Hedley, Alison M. Smith, Lorraine Barber, Josephine Craig, Annabelle Déjardin, Helma Tatge, Trevor L. Wang, Cathie Martin
Publikováno v:
Plant Journal
Plant Journal, Wiley, 1999, 17 (4), pp.353-362. ⟨10.1046/j.1365-313X.1999.00382.x⟩
Plant Journal, Wiley, 1999, 17 (4), pp.353-362. ⟨10.1046/j.1365-313X.1999.00382.x⟩
Summary The biochemical and molecular basis of the wrinkled-seeded phenotype ofrug4mutants of pea (Pisum sativumL.) has been investigated. Mutant embryos have reduced starch contents and only 5% of the sucrose synthase activity of wild-type embryos d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c47edf71be8aba8921b6f83a305998b
https://hal.inrae.fr/hal-02967569
https://hal.inrae.fr/hal-02967569