Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Lorraine, Harper"'
Autor:
Jeremiah Hwee, Lorraine Harper, Qinggong Fu, Krishnarajah Nirantharakumar, George Mu, Rupert W. Jakes
Publikováno v:
ERJ Open Research, Vol 10, Iss 3 (2024)
Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare but serious disease characterised by the combination of small-to-medium vessel vasculitis, blood and tissue eosinophilia, and asthma and/or sinonasal disease. This study estima
Externí odkaz:
https://doaj.org/article/b55f5501295946849e27117c8b899cfb
Autor:
Emma Knowles, Lorraine Harper, Jenny Hewison, Peter Thompson, Matthew R Mulvey, James Fenton, Helen Harris-Joseph, Lisa Ann Cotterill, Kieran Lee, Chris James Stevenson, Hein Heuvelman, Clare McVicker, Maria Magdalena Razalan, Brad Ebanks
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Objectives The objective of this study is to investigate early-to-late postdoctoral clinical academic progression and the experiences of NIHR Clinical Lectureship (CL) fellows, considering enablers and barriers to success, and identifying the factors
Externí odkaz:
https://doaj.org/article/c9888dd9538c46ee9dcb8413ad1d3533
Autor:
Rasiah Thayakaran, Ruchika Goel, Nicola J. Adderley, Joht Singh Chandan, Dawit Zemedikun, Krishnarajah Nirantharakumar, Lorraine Harper
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Background Granulomatosis with polyangiitis (GPA) is small vessel vasculitis with heterogeneous clinical presentation. In the present population-based cohort study, we classified patients with GPA based on clinical features at presentation u
Externí odkaz:
https://doaj.org/article/0e96fffa4b724e70a180e07bb701342a
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
Chronic kidney disease (CKD) describes the long-term condition of impaired kidney function from any cause. CKD is common and associated with a wide array of complications including higher mortality, cardiovascular disease, hypertension, insulin resis
Externí odkaz:
https://doaj.org/article/52a81f3ee1dd413c8f39ea2ba1785193
Autor:
David Jayne, Michael Walsh, Peter A Merkel, Chen Au Peh, Wladimir Szpirt, Xavier Puéchal, Shouichi Fujimoto, Carmel Hawley, Nader Khalidi, Rachel Jones, Oliver Flossmann, Ron Wald, Louis Girard, Adeera Levin, Gina Gregorini, Lorraine Harper, William Clark, Christian Pagnoux, Ulrich Specks, Lucy Smyth, Toshiko Ito-Ihara, Janak de Zoysa, Biljana Brezina, Andrea Mazzetti, Carol A McAlear, Donna Reidlinger, Samir Mehta, Natalie Ives, Elizabeth A Brettell, Hugh Jarrett, Keith Wheatley, Elizabeth Broadhurst, Alina Casian, Charles D Pusey
Publikováno v:
Health Technology Assessment, Vol 26, Iss 38 (2022)
Background: Anti-neutrophil cytoplasm antibody-associated vasculitis is a multisystem, autoimmune disease that causes organ failure and death. Physical removal of pathogenic autoantibodies by plasma exchange is recommended for severe presentations, a
Externí odkaz:
https://doaj.org/article/d0a874aa7a77433586be6d35e45e9780
Autor:
Rachel E. Lamerton, Edith Marcial-Juarez, Sian E. Faustini, Marisol Perez-Toledo, Margaret Goodall, Siân E. Jossi, Maddy L. Newby, Iain Chapple, Thomas Dietrich, Tonny Veenith, Adrian M. Shields, Lorraine Harper, Ian R. Henderson, Julie Rayes, David C. Wraith, Steve P. Watson, Max Crispin, Mark T. Drayson, Alex G. Richter, Adam F. Cunningham
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Antibodies specific for the spike glycoprotein (S) and nucleocapsid (N) SARS-CoV-2 proteins are typically present during severe COVID-19, and induced to S after vaccination. The binding of viral antigens by antibody can initiate the classical complem
Externí odkaz:
https://doaj.org/article/e96e183f4c0140d195866a01fcba3220
Autor:
Alvin H. K. Karangizi, May Al-Shaghana, Sarah Logan, Sherwin Criseno, Rachel Webster, Kristien Boelaert, Peter Hewins, Lorraine Harper
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insufficiency (AI) on withdr
Externí odkaz:
https://doaj.org/article/193f28d8eef64777b7cc775c7653d507
Autor:
Dimitrios Chanouzas, Julie Anne G. McGregor, Peter Nightingale, Alan D. Salama, Wladimir M. Szpirt, Neil Basu, Matthew David Morgan, Caroline J. Poulton, Juliana Bordignon Draibe, Elizabeth Krarup, Paula Dospinescu, Jessica Anne Dale, William Franklin Pendergraft, Keegan Lee, Martin Egfjord, Susan L. Hogan, Lorraine Harper
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Intravenous pulse methylprednisolone (MP) is commonly included in the management of severe ANCA associated vasculitis (AAV) despite limited evidence of benefit. We aimed to evaluate outcomes in patients who had, or had not receive
Externí odkaz:
https://doaj.org/article/d35384d1bd6b44a894c8b93db0513a14
Autor:
Dimitrios Chanouzas, Michael Sagmeister, Lovesh Dyall, Phoebe Sharp, Lucy Powley, Serena Johal, Jessica Bowen, Peter Nightingale, Charles J. Ferro, Matthew D. Morgan, Paul Moss, Lorraine Harper
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-10 (2018)
Abstract Background Cardiovascular disease is a leading cause of death in ANCA-associated vasculitis (AAV). An expansion of CD4+CD28null T cells is seen mainly in cytomegalovirus (CMV)-seropositive individuals and has been linked to increased cardiov
Externí odkaz:
https://doaj.org/article/b41be7dea3974d7ca0ac692fada56293
Autor:
Ingeborg M. Bajema, Jan A. Bruijn, Alina Casian, Maria C. Cid, Elena Csernok, Emma van Daalen, Lorraine Harper, Thomas Hauser, Mark A. Little, Raashid A. Luqmani, Alfred Mahr, Cristina Ponte, Alan Salama, Mårten Segelmark, Kazuo Suzuki, Jan Sznajd, Y.K. Onno Teng, Augusto Vaglio, Kerstin Westman, David Jayne
Publikováno v:
Kidney International Reports, Vol 2, Iss 6, Pp 1018-1031 (2017)
The 2016 European Vasculitis Society (EUVAS) meeting, held in Leiden, the Netherlands, was centered around phenotypic subtyping in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). There were parallel meetings of the EUVAS pet
Externí odkaz:
https://doaj.org/article/bcb7177b973744f5a8809b661584a291