Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Lornella Seeneevassen"'
1
Akademický článek
Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor
Autor: Lornella Seeneevassen, Anissa Zaafour, Elodie Sifré, Coralie Genevois, Tra Ly Nguyen, Yasmine Pobiedonoscew, Alban Giese, Jérôme Guignard, Camille Tiffon, Benoit Rousseau, Anne-Aurélie Raymond, Geneviève Belleannée, Hélène Boeuf, Caroline Gronnier, Océane C. B. Martin, Julie Giraud, Philippe Lehours, Pierre Dubus, Christine Varon
Publikováno v: Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Gastric cancer’s (GC) bad prognosis is usually associated with metastatic spread. Invasive cancer stem cells (CSC) are considered to be the seed of GC metastasis and not all CSCs are able to initiate metastasis. Targeting these aggressive
Externí odkaz: https://doaj.org/article/f3c91b91bd3d4c56a8a9fbd0497898b6
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2
Akademický článek
TAZ Controls Helicobacter pylori-Induced Epithelial–Mesenchymal Transition and Cancer Stem Cell-Like Invasive and Tumorigenic Properties
Autor: Camille Tiffon, Julie Giraud, Silvia Elena Molina-Castro, Sara Peru, Lornella Seeneevassen, Elodie Sifré, Cathy Staedel, Emilie Bessède, Pierre Dubus, Francis Mégraud, Philippe Lehours, Océane C.B. Martin, Christine Varon
Publikováno v: Cells, Vol 9, Iss 6, p 1462 (2020)
Helicobacter pylori infection, the main risk factor for gastric cancer (GC), leads to an epithelial–mesenchymal transition (EMT) of gastric epithelium contributing to gastric cancer stem cell (CSC) emergence. The Hippo pathway effectors yes-associa
Externí odkaz: https://doaj.org/article/1561b2b429034b62a76430f8af6d91bd
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3
CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma
Autor: Julie Giraud, Lornella Seeneevassen, Benoit Rousseau, Damien Bouriez, Elodie Sifré, Alban Giese, Tra Ly Nguyen, Camille Tiffon, Yannick Lippi, Lamia Azzi-Martin, Julie Pannequin, Armelle Ménard, Emilie Bessède, Cathy Staedel, Francis Mégraud, Geneviève Belleannée, Philippe Lehours, Caroline Gronnier, Pierre Dubus, Christine Varon
Publikováno v: Gastric Cancer
Gastric Cancer, In press, 26 (2), pp.234-249. ⟨10.1007/s10120-022-01357-y⟩
Background Cancer stem cells (CSCs) are at the origin of tumour initiation and progression in gastric adenocarcinoma (GC). However, markers of metastasis-initiating cells remain unidentified in GC. In this study, we characterized CD44 variants expres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33518a9aea0738828443f6ece3fdbf63
https://doi.org/10.1007/s10120-022-01357-y
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4
The cytolethal distending toxin modulates cell differentiation and elicits epithelial to mesenchymal transition
Autor: Lamia Azzi-Martin, Valentin Touffait-Calvez, Maude Everaert, Ruxue Jia, Elodie Sifré, Lornella Seeneevassen, Christine Varon, Pierre Dubus, Armelle Ménard
We are frequently exposed to bacterial genotoxins, such as cytolethal distending toxin (CDT), a prevalent heterotrimeric toxin whose active moiety is its CdtB subunit. CdtB triggers potent DNA damage, predisposing factors in the development of cancer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49de3bad3c0544d9d44c8035ad90a4b1
https://doi.org/10.1101/2022.04.06.487255
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5
Leukaemia inhibitory factor in gastric cancer: friend or foe?
Autor: Lornella Seeneevassen, Océane C. B. Martin, Philippe Lehours, Pierre Dubus, Christine Varon
Publikováno v: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 25(2)
IL-6 family cytokine leukaemia inhibitory factor (LIF) study has deciphered a variety of effects, in physiology as well as pathology. Despite the sudden arousal in LIF interest in cancers, its study in the gastric cancer (GC) context has been put asi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f931ee7195b43a794d420572ee3a1fe9
https://pubmed.ncbi.nlm.nih.gov/35106710
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7
Helicobacters and cancer, not only gastric cancer?
Autor: Pirjo Spuul, Christine Varon, Armelle Ménard, Lornella Seeneevassen, Sadia Khalid, Lamia Azzi-Martin
Publikováno v: Seminars in cancer biology. 86(Pt 2)
The Helicobacter genus actually comprises 46 validly published species divided into two main clades: gastric and enterohepatic Helicobacters. These bacteria colonize alternative sites of the digestive system in animals and humans, and contribute to i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa11b45d9d3bf96ed646a80fa4d6733
https://pubmed.ncbi.nlm.nih.gov/34425210
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8
TAZ Controls Helicobacter pylori-Induced Epithelial–Mesenchymal Transition and Cancer Stem Cell-Like Invasive and Tumorigenic Properties
Autor: Sara Peru, Philippe Lehours, Silvia Molina-Castro, Francis Mégraud, Lornella Seeneevassen, Elodie Sifré, Cathy Staedel, Océane C. B. Martin, Emilie Bessède, Christine Varon, Julie Giraud, Camille Tiffon, Pierre Dubus
Publikováno v: Cells
Cells, Vol 9, Iss 1462, p 1462 (2020)
Cells, MDPI, 2020, 9 (6), pp.1462. ⟨10.3390/cells9061462⟩
Volume 9
Issue 6
Cells, 2020, 9 (6), pp.1462. ⟨10.3390/cells9061462⟩
Cells, vol.9(6), pp.1-21
Kérwá
Universidad de Costa Rica
instacron:UCR
Helicobacter pylori infection, the main risk factor for gastric cancer (GC), leads to an epithelial&ndash
mesenchymal transition (EMT) of gastric epithelium contributing to gastric cancer stem cell (CSC) emergence. The Hippo pathway effectors ye
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3ae7823783bc53c4ce3b8738ac0e58
http://europepmc.org/articles/PMC7348942
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9
Leukaemia Inhibitory Factor (LIF) Inhibits Cancer Stem Cells Tumorigenic Properties through Hippo Kinases Activation in Gastric Cancer
Autor: Océane C B Martin, Cathy Staedel, Philippe Lehours, Julie Giraud, Silvia Molina-Castro, Camille Tiffon, Elodie Sifré, Clémentine Beauvoit, Lornella Seeneevassen, Hélène Boeuf, Francis Mégraud, Pierre Dubus, Christine Varon
Publikováno v: Cancers
Cancers, 2020, 12 (8), pp.2011. ⟨10.3390/cancers12082011⟩
Volume 12
Issue 8
Cancers, MDPI, 2020, 12 (8), pp.2011. ⟨10.3390/cancers12082011⟩
Cancers (Basel), vol.12(8), pp.1-24
Kérwá
Universidad de Costa Rica
instacron:UCR
Cancers, Vol 12, Iss 2011, p 2011 (2020)
Cancer stem cells (CSCs) present chemo-resistance mechanisms contributing to tumour maintenance and recurrence, making their targeting of utmost importance in gastric cancer (GC) therapy. The Hippo pathway has been implicated in gastric CSC propertie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d6c5fcbacafb17345f5f86f812f39c
https://doi.org/10.3390/cancers12082011
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10
Orthotopic Patient-Derived Xenografts of Gastric Cancer to Decipher Drugs Effects on Cancer Stem Cells and Metastatic Dissemination
Autor: Damien Bouriez, C Gronnier, Julie Giraud, Benoit Rousseau, Lornella Seeneevassen, Alban Giese, Elodie Sifré, Pierre Dubus, Christine Varon, Philippe Lehours, Francis Mégraud
Publikováno v: Cancers, Vol 11, Iss 4, p 560 (2019)
Cancers
Cancers, MDPI, 2019, 11 (4), pp.560. ⟨10.3390/cancers11040560⟩
Cancers, 2019, 11 (4), pp.560. ⟨10.3390/cancers11040560⟩
Volume 11
Issue 4
Gastric cancer is the third leading cause of cancer mortality worldwide. Cancer stem cells (CSC) are at the origin of tumor initiation, chemoresistance, and the formation of metastases. However, there is a lack of mouse models enabling the study of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5cacf537866dc24185c1efa88424ae
https://www.mdpi.com/2072-6694/11/4/560
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