Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lorna Mullan"'
Autor:
Louise H. W. Kung, Lorna Mullan, Jamie Soul, Ping Wang, Kazutoshi Mori, John F. Bateman, Michael D. Briggs, Raymond P. Boot-Handford
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-13 (2019)
Abstract Background Osteoarthritis has been associated with a plethora of pathological factors and one which has recently emerged is chondrocyte endoplasmic reticulum (ER) stress. ER stress is sensed by key ER-resident stress sensors, one of which is
Externí odkaz:
https://doaj.org/article/a4f7bbd62ff44cc7942e5f91d11de813
Autor:
Trevor L Cameron, Katrina M Bell, Irma L Gresshoff, Lisa Sampurno, Lorna Mullan, Joerg Ermann, Laurie H Glimcher, Raymond P Boot-Handford, John F Bateman
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005505 (2015)
Schmid metaphyseal chondrodysplasia (MCDS) involves dwarfism and growth plate cartilage hypertrophic zone expansion resulting from dominant mutations in the hypertrophic zone collagen, Col10a1. Mouse models phenocopying MCDS through the expression of
Externí odkaz:
https://doaj.org/article/041eedcd119540089142ffa6690becbb
Autor:
John F. Bateman, Mitra Forouhan, E.J. Mularczyk, Kung Lh, Briggs, Wragg Jm, Royston Goodacre, Raymond P. Boot-Handford, Lorna Mullan, Eileithyia Swanton
Publikováno v:
Yearbook of Paediatric Endocrinology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2b2ccc534a06a4a5050f9251e36897
https://doi.org/10.1530/ey.15.5.2
https://doi.org/10.1530/ey.15.5.2
Publikováno v:
International Journal of Experimental Pathology. 95:A1-A38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6977650f7d661f5976edfeab7b855a03
https://doi.org/10.1111/iep.12078
https://doi.org/10.1111/iep.12078
Autor:
Michael D. Briggs, Claire L. Hartley, Peter A. Bell, Maryline Fresquet, Sarah M. Edwards, Lorna Mullan, Raymond P. Boot-Handford
Publikováno v:
Human Molecular Genetics
Mutant matrilin-3 (V194D) forms non-native disulphide bonded aggregates in the rER of chondrocytes from cell and mouse models of multiple epiphyseal dysplasia (MED). Intracellular retention of mutant matrilin-3 causes endoplasmic reticulum (ER) stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f669d05c21f225bee63468d28a8cf74
https://doi.org/10.1093/hmg/ddt383
https://doi.org/10.1093/hmg/ddt383
Autor:
Raymond P. Boot-Handford, Irma Gresshoff, Joerg Ermann, Trevor L. Cameron, Lorna Mullan, Katrina M. Bell, John F. Bateman, Lisa Sampurno, Laurie H. Glimcher
Publikováno v:
PLoS Genetics
Cameron, T L, Bell, K M, Gresshoff, I L, Sampurno, L, Mullan, L, Ermann, J, Glimcher, L H, Boot-Handford, R P & Bateman, J F 2015, ' XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease. ', PL o S Genetics, vol. 11, no. 9 . https://doi.org/10.1371/journal.pgen.1005505
PLoS Genetics, Vol 11, Iss 9, p e1005505 (2015)
Cameron, T L, Bell, K M, Gresshoff, I L, Sampurno, L, Mullan, L, Ermann, J, Glimcher, L H, Boot-Handford, R P & Bateman, J F 2015, ' XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease. ', PL o S Genetics, vol. 11, no. 9 . https://doi.org/10.1371/journal.pgen.1005505
PLoS Genetics, Vol 11, Iss 9, p e1005505 (2015)
Schmid metaphyseal chondrodysplasia (MCDS) involves dwarfism and growth plate cartilage hypertrophic zone expansion resulting from dominant mutations in the hypertrophic zone collagen, Col10a1. Mouse models phenocopying MCDS through the expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae22f3c41798a1e15a9a1ff07d68636
https://doi.org/10.1371/journal.pgen.1005505
https://doi.org/10.1371/journal.pgen.1005505