Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lorna Morris"'
Autor:
Sanjeevan Jahagirdar, Lorna Morris, Nirupama Benis, Oddvar Oppegaard, Mattias Svenson, Ole Hyldegaard, Steinar Skrede, Anna Norrby-Teglund, INFECT Study group, Vitor A. P. Martins dos Santos, Edoardo Saccenti
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Necrotising soft tissue infections (NSTIs) are rapidly progressing bacterial infections usually caused by either several pathogens in unison (polymicrobial infections) or Streptococcus pyogenes (mono-microbial infection). These in
Externí odkaz:
https://doaj.org/article/6a62119b012d45339f67890163529c32
Autor:
Stamatia Papoutsopoulou, Lorna Morris, Andrew Bayliff, Thomas Mair, Hazel England, Massimiliano Stagi, François Bergey, Mohammad Tauqeer Alam, Raheleh Sheibani-Tezerji, Philip Rosenstiel, Werner Müller, Vitor A. P. Martins Dos Santos, Barry J. Campbell
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 757 (2022)
The NFκB transcription factors are major regulators of innate immune responses, and NFκB signal pathway dysregulation is linked to inflammatory disease. Here, we utilised bone marrow-derived macrophages from the p65-DsRedxp/IκBα-eGFP transgenic s
Externí odkaz:
https://doaj.org/article/4166ff8a12b24b59adc6b5384f9cae5f
Autor:
Katie Lloyd, Stamatia Papoutsopoulou, Emily Smith, Philip Stegmaier, Francois Bergey, Lorna Morris, Madeleine Kittner, Hazel England, Dave Spiller, Mike H. R. White, Carrie A. Duckworth, Barry J. Campbell, Vladimir Poroikov, Vitor A. P. Martins dos Santos, Alexander Kel, Werner Muller, D. Mark Pritchard, Chris Probert, Michael D. Burkitt, The SysmedIBD Consortium
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 11 (2020)
Inflammatory bowel diseases (IBDs) cause significant morbidity and mortality. Aberrant NF-κB signalling is strongly associated with these conditions, and several established drugs influence the NF-κB signalling network to exert their effect. This s
Externí odkaz:
https://doaj.org/article/98e510497b174f5483defce389417b32
Autor:
Hazel England, Emily Smith, Carrie A. Duckworth, Lorna Morris, Chris Probert, Barry J. Campbell, Katie A. Lloyd, Vitor A. P. Martins dos Santos, Stamatia Papoutsopoulou, Mike Hr White, Francois Bergey, Madeleine Kittner, Werner Müller, D. Mark Pritchard, Michael D. Burkitt, Vladimir Poroikov, Alexander E. Kel, Dave Spiller, Philip Stegmaier
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
DISEASE MODELS & MECHANISMS
Disease Models & Mechanisms, Vol 13, Iss 11 (2020)
SysmedIBD consortium, Lloyd, K, Papoutsopoulou, S, Smith, E, Stegmaier, P, Bergey, F, Morris, L, Kittner, M, England, H, Spiller, D, White, M, Campbell, B J, Duckworth, C A, Poroikov, V, Martins dos Santos, V AP, Kel, A, Muller, W, Pritchard, D M, Probert, C & Burkitt, M D 2020, ' Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease ', DMM Disease Models and Mechanisms . https://doi.org/10.1242/dmm.044040
Disease models & mechanisms
article-version (VoR) Version of Record
DISEASE MODELS & MECHANISMS
Disease Models & Mechanisms, Vol 13, Iss 11 (2020)
SysmedIBD consortium, Lloyd, K, Papoutsopoulou, S, Smith, E, Stegmaier, P, Bergey, F, Morris, L, Kittner, M, England, H, Spiller, D, White, M, Campbell, B J, Duckworth, C A, Poroikov, V, Martins dos Santos, V AP, Kel, A, Muller, W, Pritchard, D M, Probert, C & Burkitt, M D 2020, ' Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease ', DMM Disease Models and Mechanisms . https://doi.org/10.1242/dmm.044040
Disease models & mechanisms
Inflammatory bowel diseases (IBDs) cause significant morbidity and mortality. Aberrant NF-κB signalling is strongly associated with these conditions, and several established drugs influence the NF-κB signalling network to exert their effect. This s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651df354d20b7284c4736aee643dd192
https://pubmed.ncbi.nlm.nih.gov/32958515
https://pubmed.ncbi.nlm.nih.gov/32958515
Autor:
Fiona M. Blows, Sarah-Jane Dawson, Jelle Wesseling, Ian W. Brock, William J. Howat, Wilma E. Mesker, Veli-Matti Kosma, Penny Coulson, Leigh-Anne McDuffus, Rainer Fagerholm, Sarah E Pinder, Carolien H.M. van Deurzen, Angela Cox, Lorna Morris, Malcolm W.R. Reed, Arto Mannermaa, Louise Jones, Carl Blomqvist, Reijo Sironen, Daniel W. Visscher, Vesa Kataja, Annegien Broeks, Janet E. Olson, Simon S. Cross, Patrycja Gazinska, Mark E. Sherman, Marjanka K. Schmidt, Joyce Sanders, Manjeet K. Bolla, Jonine D. Figueroa, Caroline M. Seyaneve, Paul D.P. Pharoah, Elena Provenzano, Douglas F. Easton, Päivi Heikkilä, Mark N. Brook, Elinor J. Sawyer, Jose Ignacio Arias Perez, Javier Benítez, Heli Nevanlinna, Montserrat Garcia-Closas, Peter Devillee, Jolanta Lissowska, Primitiva Menéndez, Carlos Caldas, Louise A. Brinton, Nicola Johnson, Jodi Miller, Frances Daley, Fergus J. Couch, H. Raza Ali, Antoinette Hollestelle
Publikováno v:
The Journal of Pathology: Clinical Research. 1:18-32
Breast cancer risk factors and clinical outcomes vary by tumour marker expression. However, individual studies often lack the power required to assess these relationships, and large-scale analyses are limited by the need for high throughput, standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed8b8278dfb69fb95c11313469f24d7
https://doi.org/10.1002/cjp2.3
https://doi.org/10.1002/cjp2.3
Autor:
Sarah-Jane Dawson, Ali Hr, Paul D.P. Pharoah, Carlos Caldas, James D. Brenton, Lorna Morris, Nicholas A. Walton, Betania Mahler-Araujo, Mike Irwin, Elena Provenzano, Fiona M. Blows
Publikováno v:
British Journal of Cancer
Background: High-throughput evaluation of tissue biomarkers in oncology has been greatly accelerated by the widespread use of tissue microarrays (TMAs) and immunohistochemistry. Although TMAs have the potential to facilitate protein expression profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246d1d913a8dc1d9fe8bc529b0861a40
http://europepmc.org/articles/PMC3593538
http://europepmc.org/articles/PMC3593538
Autor:
Lorna Morris, Jim Davies, Peter H Maccallum, Andrew Tsui, James D. Brenton, Steve Harris, Carlos Caldas, Charles Crichton, William J. Howat
Publikováno v:
BMC Bioinformatics
Background The use of tissue microarrays (TMA) and advances in digital scanning microscopy has enabled the collection of thousands of tissue images. There is a need for software tools to annotate, query and share this data amongst researchers in diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c325ebafc2926d59f3723da900de2f20
http://www.dspace.cam.ac.uk/handle/1810/244600
http://www.dspace.cam.ac.uk/handle/1810/244600
Autor:
Lorna Morris, Nicholas A. Walton, James D. Brenton, Guy Rixon, Jack Lewis, Carlos Caldas, Peter H Maccallum, Asif Akram, Mike Irwin, Eduardo Gonzalez-Solares
Publikováno v:
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences. 368(1925)
This paper describes ‘PathGrid’—an analysis and data integration system, developed initially to meet the demands in the analysis of medical microscopy imaging data. An overview of the current system is given, describing the techniques used in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2656f31d84a45aa9e57dff656136f2a1
https://pubmed.ncbi.nlm.nih.gov/20643686
https://pubmed.ncbi.nlm.nih.gov/20643686
Autor:
Paul J. Kersey, Nadeem Faruque, Lorna Morris, Karine Michoud, Tamara Kulikova, Peter McLaren, Alexandre Gattiker, Lawrence Bower, Alexander Kanapin, Carola Kanz, Ingmar Reuter, Robert Petryszak, Alan Horne, Laurent Duret, Isabelle Phan, Rolf Apweiler, Britt Reimholz, Ujjwal Das, Karyn Duggan, Simon Penel
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2005, 33 (Database issue), pp.D297-302. ⟨10.1093/nar/gki039⟩
Nucleic Acids Research, Oxford University Press, 2005, 33 (Database issue), pp.D297-302. ⟨10.1093/nar/gki039⟩
Nucleic Acids Research, 2005, 33 (Database issue), pp.D297-302. ⟨10.1093/nar/gki039⟩
Nucleic Acids Research, Oxford University Press, 2005, 33 (Database issue), pp.D297-302. ⟨10.1093/nar/gki039⟩
Integr8 is a new web portal for exploring the biology of organisms with completely deciphered genomes. For over 190 species, Integr8 provides access to general information, recent publications, and a detailed statistical overview of the genome and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27870855b2c0cae8c73bd9d219d07d42
https://hal.science/hal-00427773
https://hal.science/hal-00427773
Autor:
Lorna Morris
Publikováno v:
Computer Methods in Biomechanics and Biomedical Engineering. 11:593-593
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ad0c78dbd7e711302af241b2249e863
https://doi.org/10.1080/10255840802475566
https://doi.org/10.1080/10255840802475566