Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lorna M, Cryan"'
Autor:
George N. Naumov, Judah Folkman, Randolph S. Watnick, Lars A. Akslen, Oddbjorn Straume, Karl-Henning Kalland, Kamila Naxerova, Soo-Young Kang, Michael Lampa, Elise R. Bender, Anne M. Oyan, Trond H. Bø, Eugene Lifshits, Anna Blois, Lorna M. Cryan, David Zurakowski, Katherine Novak, Michael S. Rogers
PDF - 120K, Supplementary Methods and legends for Supplementary Figures 1 through 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d39b13f33c4d104b3ddc250bb8dbe25
https://doi.org/10.1158/1541-7786.22511149
https://doi.org/10.1158/1541-7786.22511149
Autor:
George N. Naumov, Judah Folkman, Randolph S. Watnick, Lars A. Akslen, Oddbjorn Straume, Karl-Henning Kalland, Kamila Naxerova, Soo-Young Kang, Michael Lampa, Elise R. Bender, Anne M. Oyan, Trond H. Bø, Eugene Lifshits, Anna Blois, Lorna M. Cryan, David Zurakowski, Katherine Novak, Michael S. Rogers
PDF - 254K, Supplemental Figure 1: In vivo proliferation of angiogenic and non-angiogenic cell clones. Supplemental Figure 2: Chromosomal locations of genes with relative overexpression in either angiogenic or revertant clones. Supplemental Figure 3:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2840e66b0b57dfe1809c6a721fb80d
https://doi.org/10.1158/1541-7786.22511152
https://doi.org/10.1158/1541-7786.22511152
Autor:
Lorna M. Cryan, Tsz-Ming Tsang, Jessica Stiles, Lauren Bazinet, Sai Lun Lee, Samuel Garrard, Erika Madrian, Cody Roberts, Jessie Payne, Andrew Jensen, Arthur E. Frankel, P. Christine Ackroyd, Kenneth A. Christensen, Michael S. Rogers
Publikováno v:
Angiogenesis. 25:397-410
Anthrax protective antigen (PA) is a potent inhibitor of pathological angiogenesis with an unknown mechanism. In anthrax intoxication, PA interacts with capillary morphogenesis gene 2 (CMG2) and tumor endothelial marker 8 (TEM8). Here, we show that C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101c1169053690fbf1b65582523a87ce
https://doi.org/10.1007/s10456-022-09833-w
https://doi.org/10.1007/s10456-022-09833-w
Autor:
Michael S Rogers, Lorna M Cryan, Kaiane A Habeshian, Lauren Bazinet, Thomas P Caldwell, P Christine Ackroyd, Kenneth A Christensen
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39911 (2012)
Anti-angiogenic therapies are effective for the treatment of cancer, a variety of ocular diseases, and have potential benefits in cardiovascular disease, arthritis, and psoriasis. We have previously shown that anthrax protective antigen (PA), a non-p
Externí odkaz:
https://doaj.org/article/55c5e1601b864d598297d7ee12903fa7
Autor:
Lauren Bazinet, Sai Lun Lee, P. Christine Ackroyd, Michael S. Rogers, Samuel Garrard, Jessie Payne, Kenneth A. Christensen, Tsz-Ming Tsang, Cody Roberts, Lorna M. Cryan, Jessica Stiles
Pathological angiogenesis contributes to diseases as varied as cancer and corneal neovascularization. The vascular endothelial growth factor (VEGF) - VEGF receptor 2 (KDR/VEGFR2) axis has been the major target for treating pathological angiogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50106cb83127e1464d19e67edbbd88c
Autor:
Jordan G. Finnell, Kenneth A. Christensen, Sai Lun Lee, Michael S. Rogers, P. Christine Ackroyd, Lorna M. Cryan, Tsz-Ming Tsang, Samuel Garrard
Capillary Morphogenesis Gene 2 protein (CMG2) is a transmembrane, integrin-like receptor and the primary receptor for the anthrax toxin. In addition to its role as an anthrax toxin receptor, CMG2 has been repeatedly shown to play a role in angiogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d772356d9b69fa15a164eab77d7331b
https://doi.org/10.1101/705459
https://doi.org/10.1101/705459
Autor:
Michael Lampa, Randolph S. Watnick, Oddbjørn Straume, Trond Hellem Bø, Katherine Novak, Michael S. Rogers, Lars A. Akslen, George N. Naumov, Lorna M. Cryan, Eugene Lifshits, Elise Bender, Kamila Naxerova, Judah Folkman, Anna Blois, Karl-Henning Kalland, Soo-Young Kang, Anne Margrete Øyan, David Zurakowski
Publikováno v:
Molecular Cancer Research. 12:754-764
The angiogenic switch, a rate-limiting step in tumor progression, has already occurred by the time most human tumors are detectable. However, despite significant study of the mechanisms controlling this switch, the kinetics and reversibility of the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d0a4136d4e8a2c65effd76a587da0d
https://doi.org/10.1158/1541-7786.mcr-13-0532-t
https://doi.org/10.1158/1541-7786.mcr-13-0532-t
Autor:
Jon Clardy, Giselle Tamayo-Castillo, Michael S. Rogers, Shugeng Cao, Catalina Patricia Morales Murillo, Kaiane A. Habeshian, Lorna M. Cryan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:5885-5888
Anthrax Protective Antigen (PA) binds to two cell surface receptors, CMG2 and Tumor Endothelial Marker 8 (TEM8), which are responsible for allowing entry of anthrax toxin into host cells. PA and PASSSR, a mutated form of protective antigen, are anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6716db76dfcdcbb3512dba03e186f0a8
https://doi.org/10.1016/j.bmcl.2012.07.075
https://doi.org/10.1016/j.bmcl.2012.07.075
Publikováno v:
Cardiovascular Research. 89:661-670
Aims Aberrant retinal blood flow is a hallmark of various retinopathies and may be a causative factor in the pathology associated with these conditions. We examined the effects of pulsatile flow on bovine retinal endothelial cell (BREC) and bovine re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c092dd05df4d13dce9d862863f18782
https://doi.org/10.1093/cvr/cvq341
https://doi.org/10.1093/cvr/cvq341
Autor:
Sarah McClelland, Clare Cox, Cathal McCarthy, Roisin O’Connor, Lorna M. Cryan, Monica de Gaetano, Des Fitzgerald, Orina Belton
Publikováno v:
Atherosclerosis. 211:96-102
Objective We have previously shown that conjugated linoleic acid (CLA) regresses pre-established murine atherosclerosis. Although the exact underlying mechanisms are unclear, accumulation of macrophages and expression of inflammatory markers were red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9b1b4b9c6bccbbdf1e455b0e06bd14
https://doi.org/10.1016/j.atherosclerosis.2010.02.003
https://doi.org/10.1016/j.atherosclerosis.2010.02.003