Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lorna A. Meldrum"'
Publikováno v:
Digestion. 37:193-199
Substance P, neurotensin, bombesin and neuropeptide-Y-like immunoreactivities have been identified in nerves in gall-bladder muscle, so we studied the effects of these peptides on guinea-pig gall-bladder muscle in vitro. Substance P (0.1 mumol/l or g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dabdc2665ea75988f66d5a0ca27687e
https://doi.org/10.1159/000199500
https://doi.org/10.1159/000199500
Publikováno v:
British Journal of Pharmacology. 97:274-280
1. The effect of tachykinins on cholinergic neurotransmission was studied in an innervated tracheal tube preparation isolated from guinea-pigs anaesthetized with urethane. The tracheal tube was bathed in Krebs-Henseleit solution containing 5 microM i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24818394fadda6026d60455cb68d65f0
https://doi.org/10.1111/j.1476-5381.1989.tb11951.x
https://doi.org/10.1111/j.1476-5381.1989.tb11951.x
Publikováno v:
European Journal of Pharmacology. 105:293-299
The specific P 1 -purinoceptor agonist 2-chloroadenosine (3 × 10 −7 M to 3 × 10 −6 M) reduced the magnitude of excitatory junction potentials (e.j.p.s) recorded from guinea-pig vas deferens in response to field stimulation of the sympathetic ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e58a8ffa9276bb4b0cddbd7cb43b618
https://doi.org/10.1016/0014-2999(84)90621-6
https://doi.org/10.1016/0014-2999(84)90621-6
Publikováno v:
British Journal of Pharmacology. 82:369-374
Phosphorothioate analogues of ATP, ADP and AMP were tested on the guinea-pig taenia coli and urinary bladder. The Rp diastereoisomers of the phosphorothioate analogues, ATP-alpha-S and ADP-alpha-S were respectively 7 and 3 times more effective than t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262ad86b1004ecf8c76d4fa9e616fbe2
https://doi.org/10.1111/j.1476-5381.1984.tb10771.x
https://doi.org/10.1111/j.1476-5381.1984.tb10771.x
Autor:
Geoffrey Burnstock, Lorna A. Meldrum
Publikováno v:
European Journal of Pharmacology. 110:363-366
Electrical field stimulation of the guinea-pig seminal vesicle (4 Hz and 16 Hz) produced a biphasic response. The initial rapid twitch response was blocked by desensitisation of the P2-purinoceptor with alpha, beta-methylene ATP. The slower tonic res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf96f35685d3d3e7113da8f69a50e4f
https://doi.org/10.1016/0014-2999(85)90565-5
https://doi.org/10.1016/0014-2999(85)90565-5
Publikováno v:
European Journal of Pharmacology. 99:287-293
Electrical field stimulation of the isolated pig bladder neck preparation initiated rapid non-adrenergic, non-cholinergic nerve-mediated relaxations. A wide range of substances were examined as possible candidates for the neurotransmitter involved. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38126bc47eae8a056f4b383a16898aa8
https://doi.org/10.1016/0014-2999(84)90135-3
https://doi.org/10.1016/0014-2999(84)90135-3
Autor:
Geoffrey Burnstock, Lorna A. Meldrum
Publikováno v:
Journal of Pharmacy and Pharmacology. 37:432-434
In the guinea-pig bladder, contractile responses to substance P (0.3 μM) and VIP (3 μM) were unaffected by P2-purinoceptor desensitization with α,β-methylene ATP (3 times 10−6M), while the responses to stimulation of the non-cholinergic excitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d26534298043ad969da0362991bcf0
https://doi.org/10.1111/j.2042-7158.1985.tb03031.x
https://doi.org/10.1111/j.2042-7158.1985.tb03031.x
Autor:
Lorna A. Meldrum, Geoffrey Burnstock
Publikováno v:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 81:307-309
ATP and substance P were examined as possible mediators of non-adrenergic, non-cholinergic excitatory transmission in chicken rectum. ATP and the non-degradable ATP analogue, alpha, beta-methylene ATP, mimicked the response to nerve stimulation. Subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26634f16a83100ca0038b1e096c3f4f5
https://doi.org/10.1016/0742-8413(85)90011-8
https://doi.org/10.1016/0742-8413(85)90011-8
Autor:
Giorgio Fiore, W Kohler, K. Ewe, T. Cilluffo, Isto Nordback, Nina Kvist, Peter Skov Olsen, Ossi Teerenhovi, Onofrio G. Manghisi, H. Ruppin, L.I. Larsson, E. Amdrup, Domenico Sansonno, Pekka Vilja, H. Tsukada, A. L. Blum, R. Stoll, Paolo Detomaso, Ossi Auvinen, John Calam, Bronislaw L. Slomiany, Hardy Stern, C. Emde, Amalia Slomiany, P. Delikaris, Joanna C. Bojarski, Timo Koivula, Gaetano Bufano, Steen Seier Poulsen, Lorna A. Meldrum, Maria A. Papanice, T Gasser, Jørgen Hedemark Poulsen, Peter Bauerfeind, Ebba Nexo, J. Sarosiek, Jan Bilski, Aimo Harmoinen, C J Fimmel, Wolfram Domschke
Publikováno v:
Digestion. 37:256-258
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::896d9868ed0016dfad3a32510f2c1a25
https://doi.org/10.1159/000199510
https://doi.org/10.1159/000199510
ATP, 2-chloro-ATP, 2-methylthio-ATP and their unnatural L-enantiomers, Rp and Sp diastereoisomers of the ATP phosphorothioate analogues, ATP alpha S and ATP beta S, were tested on the guinea-pig vas deferens. The 2-substituted analogues of ATP were n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a795c26cc7bcc6e86649dead41c73f
https://europepmc.org/articles/PMC1987300/
https://europepmc.org/articles/PMC1987300/
