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of 9
pro vyhledávání: '"Lorna, Beresford"'
Autor:
John Paul Gosling, Amy Popple, Ian Kimber, Jason Williams, Clare Stretton, Rebecca J. Dearman, Kate Wicks, Gavin Maxwell, Lorna Beresford
Publikováno v:
Wicks, K, Stretton, C, Popple, A, Beresford, L, Williams, J, Maxwell, G, Gosling, J P, Kimber, I & Dearman, R J 2019, ' T lymphocyte phenotype of contact allergic patients : experience with nickel and p-phenylenediamine ', Contact dermatitis . https://doi.org/10.1111/cod.13246
BACKGROUND: There is considerable interest in understanding the immunological variables that have the greatest influence on the effectiveness of sensitization by contact allergens, particularly in the context of developing new paradigms for risk asse
Publikováno v:
Journal of Applied Toxicology. 34:489-497
Assessment of the potential allergenicity (IgE-inducing properties) of novel proteins is an important challenge in the overall safety assessment of foods. Resistance to digestion with pepsin is commonly measured to characterize allergenicity, althoug
Autor:
Lorna Beresford, Rebecca J. Dearman, Ian Kimber, Laura Bailey, Catherine J. Betts, Helen Theresa Caddick
Publikováno v:
Toxicology. 244:231-241
It has been suggested that one possible contributor to the increasing prevalence of IgE-mediated allergic diseases in Europe and the US is exposure to chemicals that may act as adjuvants. It has been reported previously that certain commonly used pht
Publikováno v:
Contact Dermatitis. 56:70-75
The murine local lymph node assay (LLNA) is used for the prospective identification of contact allergens. This method is not only accepted as a stand-alone test for the identification of contact allergenic hazard but also used increasingly for the me
Publikováno v:
Immunology. 111:118-125
Previous work has indicated that the dermis and epidermis of skin contains abundant nerve fibres closely associated with Langerhans' cells. We have investigated whether these nerve endings are necessary for inducing and evoking a contact sensitivity
Publikováno v:
Journal of applied toxicology : JAT. 34(5)
Assessment of the potential allergenicity (IgE-inducing properties) of novel proteins is an important challenge in the overall safety assessment of foods. Resistance to digestion with pepsin is commonly measured to characterize allergenicity, althoug
Autor:
Rebecca J. Dearman, Lorna Beresford, Laura Bailey, Catherine J. Betts, Helen Theresa Caddick, Ian Kimber
Publikováno v:
Journal of applied toxicology : JAT. 29(2)
During recent decades the prevalence of IgE-mediated (atopic) allergic diseases in Western Europe and the USA has been increasing dramatically. It has been suggested that one possible cause is the presence in the environment of chemicals that may act
Publikováno v:
Journal of neuroimmunology. 164(1-2)
Capsaicin-mediated depletion of neuropeptides in the skin was previously shown to abolish a dinitrocholorobenzene (DNCB)-induced contact sensitivity (CS) response. To understand the basis for this disruption, we explored whether nerve fibres innervat