Lentiviral gene therapy corrects platelet phenotype and function in patients with Wiskott-Aldrich syndrome

Autor: Marco Spinelli, Chiara Brombin, Nufar Marcus, Dario Di Silvestre, Patrizia Della Valle, Lucia Piceni Sereni, Maria Ester Bernardo, Pierluigi Mauri, Francesca Ferrua, Claudio Pignata, Lorella Cattaneo, Alessandro Aiuti, Lucia Dora Notarangelo, Armando D'Angelo, Marita Bosticardo, Stefania Giannelli, Koen van Rossem, Maddalena Migliavacca, Anna Villa, Loris Pozzi, Roula Farah, Maria Carmina Castiello, Maria Pia Cicalese

Publikováno v: Journal of allergy and clinical immunology 144 (2019): 825–838. doi:10.1016/j.jaci.2019.03.012
info:cnr-pdr/source/autori:Sereni L1, Castiello MC1, Di Silvestre D2, Della Valle P3, Brombin C4, Ferrua F5, Cicalese MP6, Pozzi L3, Migliavacca M6, Bernardo ME6, Pignata C7, Farah R8, Notarangelo LD9, Marcus N10, Cattaneo L11, Spinelli M12, Giannelli S1, Bosticardo M1, van Rossem K13, D'Angelo A3, Aiuti A5, Mauri P2, Villa A14./titolo:Lentiviral gene therapy corrects platelet phenotype and function in patients with Wiskott-Aldrich syndrome/doi:10.1016%2Fj.jaci.2019.03.012/rivista:Journal of allergy and clinical immunology/anno:2019/pagina_da:825/pagina_a:838/intervallo_pagine:825–838/volume:144
The Journal of Allergy and Clinical Immunology

BACKGROUND: Thrombocytopenia is a serious issue for all patients with classical Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT) because it causes severe and life-threatening bleeding. Lentiviral gene therapy (GT) for WAS has shown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbef2a3b9359481a3aee0ecf5da45bb
https://publications.cnr.it/doc/417797

May restricted specificity of commercially available plasmin inhibitor activity assays affect correct diagnosis of antiplasmin deficiency?

Autor: Patrizia Della Valle, Armando D'Angelo, Loris Pozzi

Publikováno v: Blood Coagulation & Fibrinolysis. 30:52-53

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd4449f8a9b5e88c2ccf27beea10c78
https://doi.org/10.1097/mbc.0000000000000788

Platelet activation is a preoperative risk factor for the development of thromboembolic complications in patients with continuous-flow left ventricular assist device

Autor: Filippo, Consolo, Giulia, Sferrazza, Giulia, Motolone, Rachele, Contri, Lorenzo, Valerio, Rosalba, Lembo, Loris, Pozzi, Patrizia, Della Valle, Michele, De Bonis, Alberto, Zangrillo, Gianfranco B, Fiore, Alberto, Redaelli, Marvin J, Slepian, Federico, Pappalardo

Publikováno v: European journal of heart failure. 20(4)

To correlate the dynamics of platelet activation with the development of thromboembolic events in patients with continuous-flow left ventricular assist device (cf-LVAD).The platelet activity state (PAS) assay was utilized to evaluate platelet activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8809309b6df3ede7739e02cfdec7e30
https://pubmed.ncbi.nlm.nih.gov/29388294

Platelet activation is a preoperative risk factor for the development of thromboembolic complications in patients with continuous-flow left ventricular assist device.

Autor: Consolo, Filippo^1,2 consolo.filippo@unisr.it, Sferrazza, Giulia^2,3, Motolone, Giulia^2,3, Contri, Rachele³, Valerio, Lorenzo^2,3, Lembo, Rosalba³, Pozzi, Loris⁴, Della Valle, Patrizia⁴, De Bonis, Michele⁵, Zangrillo, Alberto^1,3, Fiore, Gianfranco B.², Redaelli, Alberto², Slepian, Marvin J.⁶, Pappalardo, Federico^1,3

Publikováno v: European Journal of Heart Failure. Apr2018, Vol. 20 Issue 4, p792-800. 9p. 3 Charts, 3 Graphs.

Influence of Different Antithrombotic Regimens on Platelet-Mediated Thrombin Generation in Patients with Left Ventricular Assist Devices.

Autor: Consolo, Filippo, Pozzi, Loris, Pieri, Marina, Della Valle, Patrizia, Redaelli, Alberto, D'Angelo, Armando, Pappalardo, Federico

Publikováno v: ASAIO Journal; Apr2020, Vol. 66 Issue 4, p415-422, 8p