Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Loris Leboffe"'
Autor:
Gian Marco Vita, Giovanna De Simone, Loris Leboffe, Francesca Montagnani, Davide Mariotti, Stefano Di Bella, Roberto Luzzati, Andrea Gori, Paolo Ascenzi, Alessandra di Masi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The pathogenicity of group A Streptococcus (GAS) is mediated by direct bacterial invasivity and toxin-associated damage. Among the extracellular products, the exotoxin streptolysin O (SLO) is produced by almost all GAS strains. SLO is a pore forming
Externí odkaz:
https://doaj.org/article/dd379f22f44148558eba8555bb116cc0
Autor:
Alessandra Cornacchia, Maria Antonietta Saletti, Violeta Di Marzio, Romolo Salini, Cristina Marfoglia, Elga Tieri, Nicola D’Alterio, Nicla Marri, Francesca Losito, Alyexandra Arienzo, Lorenza Murgia, Giovanni Antonini, Simonetta Amatiste, Loris Leboffe, Francesco Pomilio
Publikováno v:
Italian Journal of Food Safety, Vol 9, Iss 3 (2020)
The aim of this study was to evaluate the performance of “Micro Biological Survey – MBS Test” in the enumeration of bacterial load in cow raw milk. The MBS test is based on a colorimetric method recently developed and patented by “Roma Tre”
Externí odkaz:
https://doaj.org/article/d1a1b82993924e5bbd8dd4a277d416e5
Autor:
Paolo Ascenzi, Loris Leboffe, Alessandra di Masi, Viviana Trezza, Gabriella Fanali, Magda Gioia, Massimo Coletta, Mauro Fasano
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120603 (2015)
The hydrolysis of 4-nitrophenyl esters of hexanoate (NphOHe) and decanoate (NphODe) by human serum albumin (HSA) at Tyr411, located at the FA3-FA4 site, has been investigated between pH 5.8 and 9.5, at 22.0°C. Values of Ks, k+2, and k+2/Ks obtained
Externí odkaz:
https://doaj.org/article/4c6fe4d6f5c14b458566e6666095486a
Autor:
Paolo Ascenzi, Loris Leboffe, Alessandra Pesce, Chiara Ciaccio, Diego Sbardella, Martino Bolognesi, Massimo Coletta
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e95391 (2014)
Within the globin superfamily, protoglobins (Pgb) belong phylogenetically to the same cluster of two-domain globin-coupled sensors and single-domain sensor globins. Multiple functional roles have been postulated for Methanosarcina acetivorans Pgb (Ma
Externí odkaz:
https://doaj.org/article/1b45c7a96e9140c193bf845f20452f81
Autor:
Carlo Meneghini, Loris Leboffe, Monica Bionducci, Gabriella Fanali, Massimiliano Meli, Giorgio Colombo, Mauro Fasano, Paolo Ascenzi, Settimio Mobilio
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104231 (2014)
Human serum albumin (HSA) is involved physiologically in heme scavenging; in turn, heme-albumin (HSA-heme-Fe) displays globin-like properties. Here, the allosteric effect of ibuprofen and warfarin on the local atomic structure around the ferric heme-
Externí odkaz:
https://doaj.org/article/def919422c494672bd590b340f51e7d0
Autor:
Paolo Ascenzi, Andrea Coletta, Yu Cao, Viviana Trezza, Loris Leboffe, Gabriella Fanali, Mauro Fasano, Alessandra Pesce, Chiara Ciaccio, Stefano Marini, Massimo Coletta
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69762 (2013)
Isoniazid represents a first-line anti-tuberculosis medication in prevention and treatment. This prodrug is activated by a mycobacterial catalase-peroxidase enzyme called KatG in Mycobacterium tuberculosis), thereby inhibiting the synthesis of mycoli
Externí odkaz:
https://doaj.org/article/d912f31bc02142dcb6a8c54aacb115a9
Publikováno v:
Pharmaceuticals, Vol 9, Iss 4, p 61 (2016)
Lactoferrin is an iron-binding protein present in large quantities in colostrum and in breast milk, in external secretions and in polymorphonuclear leukocytes. Lactoferrin’s main function is non-immune protection. Among several protective activitie
Externí odkaz:
https://doaj.org/article/3f9a10d43ee4473c8662136f89565db4
Publikováno v:
Current Medicinal Chemistry. 27:4907-4931
Background:Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-domain macromolecule with at least nine binding sites for endogenous and exogenous ligands. HSA displays an extraordinary ligand binding capacity as a dep
Autor:
Loris Leboffe, Isabella Giovannoni, Pierfilippo Crucitti, Filippo Longo, Paolo Ascenzi, Gaia Tabacco, Andrea Palermo, Armida Sodo, Chiara Taffon, Maria Antonietta Ricci, Silvia Manfrini, Anna Crescenzi, Roberto Cesareo, Marco Sbroscia, Alessandra di Masi
Publikováno v:
Endocrine. 67:699-707
Purpose: Recently, it has been demonstrated that Raman spectroscopy is able to differentiate between healthy parathyroid tissues and parathyroid adenoma based on the basis of a specific molecular fingerprint. However, to our knowledge, no previous st
Autor:
Nicla Marri, Alyexandra Arienzo, Simonetta Amatiste, Giovanni Antonini, Elga Ersilia Tieri, Loris Leboffe, Francesca Losito, Cristina Marfoglia, Violeta Di Marzio, Nicola D'Alterio, Lorenza Murgia, Alessandra Cornacchia, Romolo Salini, Maria Antonietta Saletti, Francesco Pomilio
Publikováno v:
Italian Journal of Food Safety
Italian Journal of Food Safety, Vol 9, Iss 3 (2020)
Italian Journal of Food Safety, Vol 9, Iss 3 (2020)
The aim of this study was to evaluate the performance of “Micro Biological Survey – MBS Test” in the enumeration of bacterial load in cow raw milk. The MBS test is based on a colorimetric method recently developed and patented by “Roma Tre”