Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Lorine Wilkinson"'
Publikováno v:
The Journal of Pathology. 238:665-676
Congenital medullary dysplasia with obstructive nephropathy is a common congenital disorder observed in paediatric patients and represents the foremost cause of renal failure. However, the molecular processes regulating normal papillary outgrowth dur
Autor:
Oliver H. Tam, David J. Pennisi, Lorine Wilkinson, Victor L. Wan, Melissa H. Little, Fatima Wazin, Frank J. Lovicu
Publikováno v:
Experimental eye research. 170
The development and growth of the vertebrate ocular lens is dependent on the regulated proliferation of an anterior monolayer of epithelial cells, and their subsequent differentiation into elongate fiber cells. The growth factor rich ocular media tha
Autor:
Sarah L. Walton, Helle Bielefeldt-Ohmann, Jereme G. Spiers, Lorine Wilkinson, Reetu R. Singh, Karen M. Moritz, Melissa H. Little, James S. M. Cuffe
Publikováno v:
The Journal of Physiology. 592:3127-3141
Maternal hypoxia is a common perturbation that can disrupt placental and thus fetal development, contributing to neonatal impairments. Recently, evidence has suggested that physiological outcomes are dependent upon the sex of the fetus, with males mo
Publikováno v:
The Journal of Pathology. 229:685-696
Crim1 is a transmembrane protein that regulates the bioavailability of growth factors such as VEGFA. Crim1(KST264)(/)(KST264) hypomorphic mice develop renal disease characterized by glomerular cysts and loss of endothelial integrity, progressing to p
Publikováno v:
The Journal of pathology. 238(5)
Congenital medullary dysplasia with obstructive nephropathy is a common congenital disorder observed in paediatric patients and represents the foremost cause of renal failure. However, the molecular processes regulating normal papillary outgrowth dur
Publikováno v:
The Journal of pathology. 229(5)
Crim1 is a transmembrane protein that regulates the bioavailability of growth factors such as VEGFA. Crim1(KST264)(/)(KST264) hypomorphic mice develop renal disease characterized by glomerular cysts and loss of endothelial integrity, progressing to p
Autor:
David J. Pennisi, J. Philippe York, Melissa H. Little, Pumin Zhang, Han Sheng Chiu, Lorine Wilkinson
Publikováno v:
Genesis (New York, N.Y. : 2000). 50(9)
Crim1 is a developmentally expressed, transmembrane protein essential for normal embryonic development. We generated mice engineered to contain a Crim1 conditional null allele by flanking exons three and four of Crim1 with unidirectional LoxP sites.
Autor:
Graham J. Galloway, Richard J Lang, Yu Leng Phua, Joan Li, Melissa H. Little, Lorine Wilkinson, Michael J Nguyen, Hikaru Hashitani, Nyoman D. Kurniawan
Publikováno v:
The Journal of pathology. 227(4)
Crim1 hypomorphic (Crim1(KST264/KST264)) mice display progressive renal disease characterized by glomerular defects, leaky peritubular vasculature, and progressive interstitial fibrosis. Here we show that 27% of these mice also present with hydroneph
Autor:
David J. Pennisi, Genevieve Kinna, Melissa H. Little, Han Sheng Chiu, David G. Simmons, Lorine Wilkinson
Publikováno v:
Placenta. 33(3)
Normal placental development and function is essential for fetal growth of eutherian mammals. Mutational studies have shown that numerous growth factors are required for placental development and differentiation of placental lineages. Here, using a g
Publikováno v:
Current topics in developmental biology. 90
The mammalian kidney may well be one of the most complex organs of postnatal life. Each adult human kidney contains on average more than one million functional filtration units, the nephrons, residing within a specialized cellular interstitium. Each