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pro vyhledávání: '"Lorinda G. Girouard"'
Autor:
Marion d.C. Molina, Thomas J. Anchordoquy, Taylor K Carson, S. Dean Allison, Lorinda G. Girouard
Publikováno v:
Drug Discovery Today. 6:463-470
The development of non-viral vectors for gene delivery has primarily focused on improving the efficiency of gene transfer in vivo. Although there is clearly a need to improve delivery efficiency, studies also indicate that the physical stability of n
Publikováno v:
Journal of pharmaceutical sciences. 87(9)
It is well established that cationic liposomes facilitate the delivery of DNA and offer substantial advantages over viral-based delivery systems. However, these synthetic vectors readily aggregate in liquid formulations which in clinical trials requi