Výsledky vyhledávání - "Lori W.E. van der Schoor"

Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obeticholic Acid Is Controlled by Constitutive Androstane Receptor through Intestinal Maturation

Autor: André A. Weber, Johan W. Jonker, Shujuan Chen, Xiaojing Yang, Robert H. Tukey, Lori W.E. van der Schoor, Elvira Mennillo

Publikováno v: Drug Metab Dispos
Drug Metabolism and Disposition, 49(1), 12-19. AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS

UDP-glucuronosyltransferase (UGT) 1A1 is the only transferase capable of conjugating serum bilirubin. However, temporal delay in the development of the UGT1A1 gene leads to an accumulation of serum bilirubin in newborn children. Neonatal humanized UG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854c6dba9938a09186caecf0f30e8539
https://doi.org/10.1124/dmd.120.000240

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