Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Lori R Roust"'
Autor:
Lee Tran, Paul D Hanavan, Latoya E Campbell, Elena De Filippis, Douglas F Lake, Dawn K Coletta, Lori R Roust, Lawrence J Mandarino, Chad C Carroll, Christos S Katsanos
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160057 (2016)
Our previous studies show reduced abundance of the β-subunit of mitochondrial H+-ATP synthase (β-F1-ATPase) in skeletal muscle of obese individuals. The β-F1-ATPase forms the catalytic core of the ATP synthase, and it is critical for ATP productio
Externí odkaz:
https://doaj.org/article/9ef4ec0d8079412183dd26eb9810abd6
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Obesity negatively impacts skeletal muscle protein metabolism, and also impairs skeletal muscle maintenance and regeneration. We analyzed muscle biopsy samples from humans with increased body mass index (BMI) (i.e. > 30 kg/m2) and controls (i.e., BMI
Externí odkaz:
https://doaj.org/article/7fe6b4c0c36f4620b99a1f21aa211246
Autor:
Luis A. Garcia, Rocio Zapata-Bustos, Samantha E. Day, Baltazar Campos, Yassin Hamzaoui, Linda Wu, Alma D. Leon, Judith Krentzel, Richard L. Coletta, Eleanna De Filippis, Lori R. Roust, Lawrence J. Mandarino, Dawn K. Coletta
Publikováno v:
Metabolites, Vol 12, Iss 3, p 222 (2022)
Skeletal muscle is highly plastic and dynamically regulated by the body’s physical demands. This study aimed to determine the plasticity of skeletal muscle DNA methylation in response to 8 weeks of supervised exercise training in volunteers with a
Externí odkaz:
https://doaj.org/article/8e388431e6704a6ca5cdad6ff28196dd
Autor:
Samantha E. Day, Richard L. Coletta, Joon Young Kim, Luis A. Garcia, Latoya E. Campbell, Tonya R. Benjamin, Lori R. Roust, Elena A. De Filippis, Lawrence J. Mandarino, Dawn K. Coletta
Publikováno v:
Epigenetics, Vol 12, Iss 4, Pp 254-263 (2017)
Obesity can increase the risk of complex metabolic diseases, including insulin resistance. Moreover, obesity can be caused by environmental and genetic factors. However, the epigenetic mechanisms of obesity are not well defined. Therefore, the identi
Externí odkaz:
https://doaj.org/article/2c36f13ad8264b419623cd94f2923daa
Autor:
Juan Carlos Leoni Moreno, D. Eric Steidley, Lori R. Roust, Victoria Gomez, Neena S. Abraham, Neej J. Patel, Rahul Pannala
Publikováno v:
Obesity Surgery. 30:3610-3614
Obesity is an important limiting factor for heart transplantation (HT) in patients with congestive heart failure (CHF). Achieving substantial weight loss is challenging in this population due to activity limitations and fluid retention. Endoscopic ba
Publikováno v:
Medicine & Science in Sports & Exercise. 54:356-356
Autor:
Tonya R. Benjamin, James A. Madura, Dawn K. Coletta, Luis A. Garcia, Samantha E. Day, Richard L. Coletta, Lori R. Roust, Lawrence J. Mandarino, Eleanna De Filippis, Baltazar Campos
Publikováno v:
Clinical Epigenetics
Background The mechanisms of weight loss and metabolic improvements following bariatric surgery in skeletal muscle are not well known; however, epigenetic modifications are likely to contribute. The aim of our study was to investigate skeletal muscle
Autor:
Elena A. De Filippis, Nathan Serrano, Lee Tran, Katon A. Kras, Christos S. Katsanos, Matthew R. Buras, Shivam H. Patel, Lori R. Roust, Chad C. Carroll, Nyssa Hoffman
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
Acute aerobic exercise induces skeletal muscle mitochondrial gene expression, which in turn can increase muscle mitochondrial protein synthesis. In this regard, the peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), is a master
Autor:
Christos S. Katsanos, Tonya R. Benjamin, Elena A. De Filippis, Katon A. Kras, Nyssa Hoffman, Lori R. Roust
Publikováno v:
Medicine & Science in Sports & Exercise. 51:445-453
Current evidence indicates mitochondrial dysfunction in humans with obesity. Acute exercise appears to enhance mitochondrial function in the muscle of nonobese humans, but its effects on mitochondrial function in muscle of humans with obesity are not
Publikováno v:
Experimental Physiology. 104:126-135
New findings What is the central question of this study? Humans with obesity have lower ATP synthesis in muscle along with lower content of the β-subunit of the ATP synthase (β-F1-ATPase), the catalytic component of the ATP synthase. Does lower syn