Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lori M. Tobias"'
Autor:
Randolph P. Matthews, Rebecca E Wrishko, Mary Beth Dorr, Diana Montgomery, Lori M. Tobias, Ka Lai Yee
Publikováno v:
Clinical Pharmacology in Drug Development. 9:330-340
Bezlotoxumab is a fully human monoclonal antibody that binds and neutralizes Clostridium difficile toxin B. This analysis investigated the potential of bezlotoxumab to induce immunogenicity in healthy phase 1 trial participants and in phase 2/3 trial
Autor:
Linda J. Obenauer-Kutner, Meredith Neumann, Sheila Jacobs, Constance Cullen, Leslie W Abad, Lori M Tobias
Publikováno v:
Analytical Biochemistry. 310:107-113
A biosensor-based assay, using a surface plasmon resonance detection system, was developed to detect and isotype anti-adenoviral antibodies in patients dosed with an adenoviral-based gene therapy vector. In the assay, whole, intact virus was immobili
Publikováno v:
Journal of immunological methods. 206(1-2)
A highly sensitive immunoassay for the quantitative measurement of recombinant interferon alfa-2b (IFN alfa-2b) in serum was developed using the ORIGEN electrochemiluminescence (ECL) detection system. The ECL assay developed uses a ruthenylated mouse