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pro vyhledávání: '"Lori M. Scarlett"'
Publikováno v:
Endocrinology. 136:1161-1167
Ames dwarf mice have a recessive defect that results in affected mice (df/df) with extremely hypocellular anterior pituitaries that generally lack somatotropes, lactotropes, and thyrotropes. We report detection of rare foci of GH+ cells by immunocyto
Publikováno v:
Mammalian Genome. 3:604-607
Autor:
Lauren T. Knapp, Sally A. Camper, Kathleen A. Mahon, Lori M. Scarlett, Philip J. Gage, Michelle L. Brinkmeier
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 10(12)
Two nonallelic dwarfing mutations in mice define genes important for pituitary development and function. Mice homozygous for either the Ames (df) or Snell (Pit 1dw) dwarf mutations exhibit severe proportional dwarfism, hypothyroidism, and infertility
Publikováno v:
Development (Cambridge, England). 122(1)
The Ames dwarf mouse transmits a recessive mutation (df) resulting in a profound anterior pituitary hypocellularity due to a general lack of thyrotropes, somatotropes and lac-totropes. These cell types are also dependent on the pituitary-specific tra