Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Lori M Hansen"'
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183324 (2017)
Epidemiologic studies have reported an inverse relationship between childhood Helicobacter pylori infection and development of allergic asthma. Because lung epithelium plays an important role in allergic asthma pathogenesis, we hypothesized that H. p
Externí odkaz:
https://doaj.org/article/468e19cf44f1447d981919a42becc109
Autor:
Roberto M Barrozo, Cara L Cooke, Lori M Hansen, Anna M Lam, Jennifer A Gaddy, Elizabeth M Johnson, Taryn A Cariaga, Giovanni Suarez, Richard M Peek, Timothy L Cover, Jay V Solnick
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003189 (2013)
Helicobacter pylori causes clinical disease primarily in those individuals infected with a strain that carries the cytotoxin associated gene pathogenicity island (cagPAI). The cagPAI encodes a type IV secretion system (T4SS) that injects the CagA onc
Externí odkaz:
https://doaj.org/article/b65e978879024fac91d09c8853f267fc
Autor:
Linda H Ta, Lori M Hansen, William E Sause, Olga eShiva, Aram eMillstein, Karen M Ottemann, Andrea R Castillo, Jay V Solnick
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 2 (2012)
The Helicobacter pylori cag pathogenicity island (cag PAI) encodes a Type IV secretion system that is more commonly found in strains isolated from patients with gastroduodenal disease than from those with asymptomatic gastritis. Genome-wide organizat
Externí odkaz:
https://doaj.org/article/bede436ffd284bbdb03283550a8ffa8e
Autor:
Sharon Perry, Bouke C de Jong, Jay V Solnick, Maria de la Luz Sanchez, Shufang Yang, Philana Ling Lin, Lori M Hansen, Najeeha Talat, Philip C Hill, Rabia Hussain, Richard A Adegbola, Joanne Flynn, Don Canfield, Julie Parsonnet
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8804 (2010)
Helicobacter pylori, a lifelong and typically asymptomatic infection of the stomach, profoundly alters gastric immune responses, and may benefit the host in protection against other pathogens. We explored the hypothesis that H. pylori contributes to
Externí odkaz:
https://doaj.org/article/12f0e542f04644978becf5121a8d1d22
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV secretion system (T4SS) and its effector CagA encoded on the cag pathogenicity Island (cagPAI) increases the risk. H. pylori PMSS1 has a multi-cagA genot
Externí odkaz:
https://doaj.org/article/59a8fdca625a4a7caee076507d95bfd8
Autor:
Emma C. Skoog, Miriam E. Martin, Roberto M. Barrozo, Lori M. Hansen, Lucy P. Cai, Seung-Joo Lee, Joseph M. Benoun, Stephen J. McSorley, Jay V. Solnick
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT The Helicobacter pylori type IV secretion system (T4SS) encoded on the cag pathogenicity island (cagPAI) secretes the CagA oncoprotein and other effectors into the gastric epithelium. During murine infection, T4SS function is lost in an immu
Externí odkaz:
https://doaj.org/article/ea71d867c36a445497d0f3395c5cbdea
Autor:
Jeanna A. Bugaytsova, Artem Piddubnyi, Iryna Tkachenko, Lena Rakhimova, Johan Olofsson Edlund, Kaisa Thorell, Harold Marcotte, Anders Lundquist, Karin Schön, Nils Lycke, Sebastian Suerbaum, Christian Schulz, Peter Malfertheiner, Lori M. Hansen, Jay V. Solnick, Roman Moskalenko, Lennart Hammarström, Thomas Borén
SUMMARYMost cases of gastric cancer are caused by chronicHelicobacter pyloriinfection, but the lack of early onco-diagnostics and a high risk for antibiotic resistance hampers early intervention through eradication ofH. pyloriinfection by antibiotics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f361f423e98ab6f6fe97be3081a2fc8e
https://doi.org/10.1101/2023.05.25.542131
https://doi.org/10.1101/2023.05.25.542131
Autor:
Emma C. Skoog, Vasilios A. Morikis, Miriam E. Martin, Greg A. Foster, Lucy P. Cai, Lori M. Hansen, Beibei Li, Jennifer A. Gaddy, Scott I. Simon, Jay V. Solnick
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Strains of Helicobacter pylori that cause ulcer or gastric cancer typically express a type IV secretion system (T4SS) encoded by the cag pathogenicity island (cagPAI). CagY is an ortholog of VirB10 that, unlike other VirB10 orthologs, has a
Externí odkaz:
https://doaj.org/article/d5a1ea5e1a5f4d1786af03886b030a49
Autor:
Jenny L. Draper, Lori M. Hansen, David L. Bernick, Samar Abedrabbo, Jason G. Underwood, Nguyet Kong, Bihua C. Huang, Allison M. Weis, Bart C. Weimer, Arnoud H. M. van Vliet, Nader Pourmand, Jay V. Solnick, Kevin Karplus, Karen M. Ottemann
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Many bacterial genomes are highly variable but nonetheless are typically published as a single assembled genome. Experiments tracking bacterial genome evolution have not looked at the variation present at a given point in time. Here, we anal
Externí odkaz:
https://doaj.org/article/01a452ee2eb94a0f9d78d0252bbc821b
Publikováno v:
Infection and immunity, vol 88, iss 6
Infect Immun
Infect Immun
Chronic Helicobacter pylori colonization in animal models often leads to downregulation of the type IV secretion system (T4SS), typically by recombination in cagY, which is an essential T4SS gene. However, 17 other cag pathogenicity island (cagPAI) g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d80554fba07f9b352b80ce340c367d7
https://escholarship.org/uc/item/36d4794r
https://escholarship.org/uc/item/36d4794r