Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Lori L. Edwards"'
Autor:
Anna Pomés, Jonas Lidholm, Rob C. Aalberse, Peter Briza, Joost A. Aalberse, Lori L. Edwards, Theo Rispens, Ninotska I. L. Derksen, Geoffrey A. Mueller
Publikováno v:
Clinical and experimental allergy, 50(3), 401-405. Wiley-Blackwell
Background Small, basic peanut proteins are often poorly extracted in pH-neutral buffers that are optimal for the extraction of peanut storage proteins such as Ara h 1. As a result, such proteins are easily missed as potential allergens. Objective To
Autor:
Lori L. Edwards, Debajyoti Ghosh, Robert E. London, Gabriele Schramm, Arnd Petersen, Helmut L. Haas, Geoffrey A. Mueller, Swati Gupta Bhattacharya
Publikováno v:
Journal of Biological Chemistry. 289:21374-21385
Cyclophilin (Cyp) allergens are considered pan-allergens due to frequently reported cross-reactivity. In addition to well studied fungal Cyps, a number of plant Cyps were identified as allergens (e.g. Bet v 7 from birch pollen, Cat r 1 from periwinkl
Autor:
Lori L. Edwards, Lalith Perera, Jill Glesner, Jay E. Slater, Anna Pomés, Robert E. London, Geoffrey A. Mueller, Lars C. Pedersen, John A. Ankney, Taruna Khurana
Publikováno v:
Molecular Immunology. 59:200-207
Bla g 1 is a major allergen from Blatella germanica and one of the primary allergens used to assess cockroach allergen exposure. The epitope of an anti-Bla g 1 scFv was mapped in order to better understand cross reactivity with other group 1 cockroac
Autor:
Barry K. Hurlburt, Soheila J. Maleki, Hsiaopo Cheng, Anna Pomés, Sanbao Ruan, Robert E. London, Allison N. Schorzman, Kenneth B. Tomer, Geoffrey A. Mueller, Jacqueline B. Nesbit, Jason Williams, Lori L. Edwards, HaJeung Park, Katina L. Johnson, Leesa J. Deterding
Publikováno v:
Allergy. 68:1546-1554
Background Recent immunological data demonstrated that dendritic cells preferentially recognize advanced glycation end product (AGE)-modified proteins, upregulate expression of the receptor for AGE (RAGE), and consequently bias the immune response to
Autor:
Matthew J. Cuneo, Lars C. Pedersen, Anna Pomés, Lori L. Edwards, Joseph M. Krahn, Jill Glesner, Rajendrakumar A. Gosavi, Robert E. London, Martin D. Chapman, Geoffrey A. Mueller
Publikováno v:
Journal of Biological Chemistry. 285:25394-25401
Group 5 allergens from house dust mites elicit strong IgE antibody binding in mite-allergic patients. The structure of Der p 5 was determined by x-ray crystallography to better understand the IgE epitopes, to investigate the biologic function in mite
Publikováno v:
Protein Expression and Purification. 70:163-171
Human DNA polymerase nu (Pol nu) is a conserved family A DNA polymerase of uncertain biological function. Physical and biochemical characterization aimed at understanding Pol nu function is hindered by the fact that, when over-expressed in Escherichi
Autor:
Aaron S. Meyer, Gary Powell, Douglas A. Lauffenburger, Marcia L. Moss, Linda G. Griffith, Miles A. Miller, Lori L. Edwards, Robert M. Petrovich
Publikováno v:
Nature Publishing Group
Scientific Reports
Scientific Reports
Dysregulation of ErbB-family signaling underlies numerous pathologies and has been therapeutically targeted through inhibiting ErbB-receptors themselves or their cognate ligands. For the latter, “decoy” antibodies have been developed to sequester
Autor:
Martin D. Chapman, Jill Glesner, Anna Pomés, Lalith Perera, Lori L. Edwards, Eugene F. DeRose, Geoffrey A. Mueller, Robert E. London, Lars C. Pedersen, Thomas A. Randall
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 46(2)
Background Der p 23 was recently identified in a European population as a major allergen and potentially a chitin binding protein. Objective This study sought to assess the importance of Der p 23 among other Dermatophagoides allergens in a North Amer
Publikováno v:
Biochimica et biophysica acta. 1850(9)
Background Mn/Fe-superoxide dismutase (SOD) is a family of enzymes essential for organisms to be able to cope with oxygen. These enzymes bound to their classical metals catalyze the dismutation of the free radical superoxide anion (O 2 − ) to H 2 O
Autor:
Robert E. London, Lori L. Edwards, L. Karla Arruda, Anna Pomés, Martin D. Chapman, Jill Glesner, Luis Caraballo, Josefina Zakzuk, Geoffrey A. Mueller, Lars C. Pedersen
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background It is not clear whether cross-reactivity or cosensitization to glutathione S-transferases (GSTs) occurs in tropical and subtropical environments. In the United States, Bla g 5 is the most important GST allergen and lack of coexposure to GS