Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Lori L. Burrows"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Type IV pili (T4P) produced by the pathogen Pseudomonas aeruginosa play a pivotal role in adhesion, surface motility, biofilm formation, and infection in humans. Despite the significance of T4P as a potential therapeutic target, key details
Externí odkaz:
https://doaj.org/article/bb927c40bd0e4cb3b57ee488b6cea7ff
Autor:
Luke N. Yaeger, Michael R. M. Ranieri, Jessica Chee, Sawyer Karabelas-Pittman, Madeleine Rudolph, Alessio M. Giovannoni, Hanjeong Harvey, Lori L. Burrows
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Biofilms are surface-associated communities of bacteria that grow in a self-produced matrix of polysaccharides, proteins, and extracellular DNA (eDNA). Sub-minimal inhibitory concentrations (sub-MIC) of antibiotics induce biofilm formation,
Externí odkaz:
https://doaj.org/article/25ec3de6b7a3429c838ec310c4126365
Autor:
Derek C. K. Chan, Lori L. Burrows
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Iron is essential for many biological functions in bacteria, but its poor solubility is a limiting factor for growth. Bacteria produce siderophores, soluble natural products that bind iron with high affinity, to overcome this challenge. Side
Externí odkaz:
https://doaj.org/article/25223bd162ca4396860f7bf31b458afa
Autor:
Matthew McCallum, Samir Benlekbir, Sheryl Nguyen, Stephanie Tammam, John L. Rubinstein, Lori L. Burrows, P. Lynne Howell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Bacterial type IV pilus-like systems catalyse the formation of pilin fibres but it is unknown how they are powered. Here, the authors present crystal and cryo-EM structures of the hexameric motor ATPases PilB and PilT from Type IVa Pilus that reveal
Externí odkaz:
https://doaj.org/article/1255c099b54940abac6f1fa7758b5856
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Bacterial type IVa pili are protein filaments used for motility and protein secretion. Here the authors present crystal structures of theGeobacter metallireducensPilB ATPase in two nucleotide states, and suggest a clockwise rotation of the central su
Externí odkaz:
https://doaj.org/article/6b3b5867680949b9922cb7cf172605e1
Autor:
Sara L. N. Kilmury, Lori L. Burrows
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Motility is an important virulence trait for many bacterial pathogens, allowing them to position themselves in appropriate locations at appropriate times. The motility structures type IV pili and flagella are also involved in sensing surface
Externí odkaz:
https://doaj.org/article/927caeb4c6384a5397ecb381df511209
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Type IV pili (T4P) are surface-exposed protein fibers that play key roles in the bacterial life cycle via surface attachment/adhesion, biofilm formation, motility, and development. The order Myxococcales (myxobacteria) are members of the class Deltap
Externí odkaz:
https://doaj.org/article/e0c0b284f6624e8ba19fae8c4a7b3697
Autor:
Tyson Carter, Ryan N. C. Buensuceso, Stephanie Tammam, Ryan P. Lamers, Hanjeong Harvey, P. Lynne Howell, Lori L. Burrows
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Type IVa pili (T4aP) are ubiquitous microbial appendages used for adherence, twitching motility, DNA uptake, and electron transfer. Many of these functions depend on dynamic assembly and disassembly of the pilus by a megadalton-sized, cell e
Externí odkaz:
https://doaj.org/article/d75a6f7fe48a44aa8b9ea8e2c2abdeae
Publikováno v:
Emerging Infectious Diseases, Vol 10, Iss 5, Pp 924-927 (2004)
Dementia developed in a patient with widespread neurologic manifestations; she died within 5 months. Pathologic findings showed granulomatous inflammation with caseation necrosis, foreign body–type giant cells, and proliferative endarteritis with v
Externí odkaz:
https://doaj.org/article/650aefce808045bc8b9f223e8bb8bbb0
Autor:
George A. Heckman, Cynthia Hawkins, Andrew Morris, Lori L. Burrows, Catherine Bergeron, Xiang Y. Han
Publikováno v:
Emerging Infectious Diseases, Vol 11, Iss 8, Pp 1316-1317 (2005)
Externí odkaz:
https://doaj.org/article/ef2ea83fea5249909f4a9b371cf03f32