Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lori J. Lorenz"'
Autor:
Shobha Anilkumar, Jessica A. Hurt, Tsuyoshi Udagawa, Joel D. Richter, Sumantra Chattarji, Mira Jakovcevski, Gary J. Bassell, Juan Marcos Alarcon, Hanoch Kaphzan, Natalie G. Farny, Lori J. Lorenz, Eric Klann, Kentaro Nagaoka, Schahram Akbarian, Maria Ivshina, Vijayalaxmi C Nalavadi
Publikováno v:
Nature medicine
Fragile X syndrome (FXS), the most common cause of inherited mental retardation and autism, is caused by transcriptional silencing of FMR1, which encodes the translational repressor fragile X mental retardation protein (FMRP). FMRP and cytoplasmic po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a446adcd5352496ed4869f8ea2957ce0
https://doi.org/10.1038/nm.3353
https://doi.org/10.1038/nm.3353
Autor:
Gary J. Bassell, Sharon A. Swanger, Vijayalaxmi C Nalavadi, Joel D. Richter, Lori J. Lorenz, Koichi Takeuchi, R. Suzanne Zukin, Jihae Shin, Jong Heon Kim, Tsuyoshi Udagawa
Publikováno v:
Molecular Cell. 47:253-266
Translational control of mRNAs in dendrites is essential for certain forms of synaptic plasticity and learning and memory. CPEB is an RNA-binding protein that regulates local translation in dendrites. Here, we identify poly(A) polymerase Gld2, deaden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73eba379fd140ec3f13fb2e57b88d9e1
https://doi.org/10.1016/j.molcel.2012.05.016
https://doi.org/10.1016/j.molcel.2012.05.016
Publikováno v:
Molecular and Cellular Biology. 26:4277-4287
CPEB-mediated translation is important in early development and neuronal synaptic plasticity. Here, we describe a new eukaryotic initiation factor 4E (eIF4E) binding protein, Neuroguidin (Ngd), and its interaction with CPEB. In the mammalian nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379e57420c9c15fb2a368b1351cfab92
https://doi.org/10.1128/mcb.02470-05
https://doi.org/10.1128/mcb.02470-05
Autor:
David Van Vactor, Lori J. Lorenz
Publikováno v:
Current Biology. 9(6):R201-R204
Recent studies of the semaphorin family of axon guidance signals and their receptors have revealed a surprising versatility in the ways that they can be used solve problems in neural development, and provided new opportunities for understanding how g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3552574bfa003d18bc58574aaa255413
Autor:
Lori J. Lorenz, Joel D. Richter
Publikováno v:
Current opinion in neurobiology. 12(3)
Synaptic efficacy, a phenomenon that may underlie long-term memory storage, is controlled in part by the regulated translation of mRNAs stored in dendrites. The molecular basis by which specific mRNAs are selected for translation is beginning to emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6818cb3e01ec07d2ecaed728d74c855e
https://pubmed.ncbi.nlm.nih.gov/12049937
https://pubmed.ncbi.nlm.nih.gov/12049937
To begin unraveling the functional significance of calcium channel diversity, we identified mutations in Dmca1D, a Drosophila calcium channel α1 subunit cDNA that we recently cloned. These mutations constitute the l(2)35Fa lethal locus, which we ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be24b553f4fff43bac6a7b7cf8aead6
https://europepmc.org/articles/PMC1460043/
https://europepmc.org/articles/PMC1460043/
Autor:
Lori J. Lorenz, Michael B. Melnick, Norbert Perrimon, Vanita Sood, Daniel F. Eberl, Paul Lasko
Publikováno v:
Genetics. 146(3)
In Drosophila melanogaster, position-effect variegation of the white gene has been a useful phenomenon by which to study chromosome structure and the genes that modify it. We have identified a new enhancer of variegation locus, Dmrnahel (hel). Deleti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d661ce7231ea80a5004ea04d76263b
https://pubmed.ncbi.nlm.nih.gov/9215899
https://pubmed.ncbi.nlm.nih.gov/9215899
Autor:
Lori J. Lorenz, Joel D. Richter
Publikováno v:
Molecular and Cellular Biology. 5:2697-2704
Xenopus laevis oocytes contain a unique group of proteins which decrease during oogenesis, bind poly(A) RNA, and possibly play a role in the regulation of translation. A monoclonal antibody generated against one of these proteins was used to screen a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c89b5e5f40f4020bf86686e4aed7eb
https://doi.org/10.1128/mcb.5.10.2697
https://doi.org/10.1128/mcb.5.10.2697
Publikováno v:
Journal of Biological Chemistry. 260:4448-4454
Messenger RNA injected Xenopus oocytes exhibit a differential capacity for translation. mRNAs translated in the free cytoplasm are translated efficiently whereas mRNAs translated on the rough endoplasmic reticulum (RER) membrane are translated ineffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9fe2cd610abd9b4be22cb7b6514a673
https://doi.org/10.1016/s0021-9258(18)89285-7
https://doi.org/10.1016/s0021-9258(18)89285-7
Autor:
Robert J. Deschenes, Randy S. Haun, Jack E. Dixon, Bernard A. Roos, Lori J. Lorenz, K. Collier
Publikováno v:
Proceedings of the National Academy of Sciences. 81:726-730
Poly(A) RNA was isolated from a rat medullary thyroid carcinoma that exhibited high levels of immunoreactive cholecystokinin (CCK). Double-stranded cDNA was synthesized from the poly(A) RNA and inserted into the Pst I site of pBR322. Bacterial coloni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55749e5e8d1c3c031c922ddbcf7d1660
https://doi.org/10.1073/pnas.81.3.726
https://doi.org/10.1073/pnas.81.3.726