Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lori Hipolito"'
Autor:
Laura Neely, Annalee Estrellado, Hong Zhang, Lori Hipolito, Karen Lundgren, Naveen Dakappagari, Francis Burrows, Shabnam Tangri
Publikováno v:
Biomarkers. 15:31-38
Hsp90 inhibitors are under investigation in multiple human clinical trials for the treatment of cancers, including myeloma, breast cancer, prostate, lung, melanoma, gastrointestinal stromal tumour and acute myeloid leukaemia. The pharmacodynamic acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d67f60daa5522c53ae477774a54c0d
https://doi.org/10.3109/13547500903261347
https://doi.org/10.3109/13547500903261347
Autor:
Maureen G. Price, Qin Yu, Henry F. Epstein, Sanford I. Bernstein, Yoko Suzuki, Jennifer A. Suggs, Chi F. Lee, Girish C. Melkani, Lori Hipolito, William A. Kronert
Publikováno v:
Journal of cell science. 124(Pt 5)
UNC-45 is a chaperone that facilitates folding of myosin motor domains. We have used Drosophila melanogaster to investigate the role of UNC-45 in muscle development and function. Drosophila UNC-45 (dUNC-45) is expressed at all developmental stages. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f4b6f1734c936258eaf3a4ead84273
https://pubmed.ncbi.nlm.nih.gov/21285246
https://pubmed.ncbi.nlm.nih.gov/21285246
Autor:
Lori Hipolito, Laura Pierce, Daniel Stenzel, Shabnam Tangri, Gerardo Ibanez, Naveen Dakappagari, Sarah Harris, Karen Lundgren, Noelito Timple
Publikováno v:
Molecular Cancer Therapeutics. 8:B35-B35
Biomarkers are increasingly being used in early phase clinical trials not only to determine pharmacodynamic activity but also as surrogate end points of clinical efficacy. BIIB021 is a synthetic small molecule that inhibits the activity of Hsp90, a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7152fd2e698f5e2559fccc2dc1e4394f
https://doi.org/10.1158/1535-7163.targ-09-b35
https://doi.org/10.1158/1535-7163.targ-09-b35