Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lori Haapanen"'
Metabolic network analysis of pre-ASD newborns and 5-year-old children with autism spectrum disorder
Autor:
Sai Sachin Lingampelly, Jane C. Naviaux, Luke S. Heuer, Jonathan M. Monk, Kefeng Li, Lin Wang, Lori Haapanen, Chelsea A. Kelland, Judy Van de Water, Robert K. Naviaux
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-22 (2024)
Abstract Classical metabolomic and new metabolic network methods were used to study the developmental features of autism spectrum disorder (ASD) in newborns (n = 205) and 5-year-old children (n = 53). Eighty percent of the metabolic impact in ASD was
Externí odkaz:
https://doaj.org/article/f4194044842e43d09eba1b4339a96378
Autor:
Benjamin I. Laufer, Yu Hasegawa, Zhichao Zhang, Casey E. Hogrefe, Laura A. Del Rosso, Lori Haapanen, Hyeyeon Hwang, Melissa D. Bauman, Judy Van de Water, Ameer Y. Taha, Carolyn M. Slupsky, Mari S. Golub, John P. Capitanio, Catherine A. VandeVoort, Cheryl K. Walker, Janine M. LaSalle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
In animal models, maternal obesity is associated with development of neurodevelopmental disorder like phenotypes. Here the authors show in a macaque model that in obese dams, cell-free fetal DNA methylation, inflammatory cytokines, and metabolites co
Externí odkaz:
https://doaj.org/article/bfda17b385eb45c399ddcbf0d2cffdd0
Autor:
Nora Céspedes, Erinn L. Donnelly, Casey Lowder, Gretchen Hansten, Delaney Wagers, Anna M. Briggs, Joseph Schauer, Lori Haapanen, Magnus Åbrink, Judy Van de Water, Shirley Luckhart
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
An increase in mast cells (MCs) and MCs mediators has been observed in malaria-associated bacteremia, however, the role of these granulocytes in malarial immunity is poorly understood. Herein, we studied the role of mouse MC protease (Mcpt) 4, an ort
Externí odkaz:
https://doaj.org/article/985c41b206bb44cd853a4a634cd60748
Autor:
Cesar P Canales, Myka L Estes, Karol Cichewicz, Kartik Angara, John Paul Aboubechara, Scott Cameron, Kathryn Prendergast, Linda Su-Feher, Iva Zdilar, Ellie J Kreun, Emma C Connolly, Jin Myeong Seo, Jack B Goon, Kathleen Farrelly, Tyler W Stradleigh, Deborah van der List, Lori Haapanen, Judy Van de Water, Daniel Vogt, A Kimberley McAllister, Alex S Nord
Publikováno v:
eLife, Vol 10 (2021)
In utero exposure to maternal immune activation (MIA) is an environmental risk factor for neurodevelopmental and neuropsychiatric disorders. Animal models provide an opportunity to identify mechanisms driving neuropathology associated with MIA. We pe
Externí odkaz:
https://doaj.org/article/8218b557ea204428b001028127541f8d
Autor:
Erinn L. Donnelly, Nora Céspedes, Gretchen Hansten, Delaney Wagers, Anna M. Briggs, Casey Lowder, Joseph Schauer, Sarah M. Garrison, Lori Haapanen, Judy Van de Water, Shirley Luckhart
Publikováno v:
ImmunoHorizons, vol 6, iss 8
Malaria-induced bacteremia has been shown to result from intestinal mast cell (MC) activation. The appearance of MCs in the ileum and increased intestinal permeability to enteric bacteria are preceded by an early Th2-biased host immune response to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9775c0701324cc5ce4e4c1e68c641179
https://escholarship.org/uc/item/4f78m7mk
https://escholarship.org/uc/item/4f78m7mk
Autor:
Nora, Céspedes, Erinn L, Donnelly, Casey, Lowder, Gretchen, Hansten, Delaney, Wagers, Anna M, Briggs, Joseph, Schauer, Lori, Haapanen, Magnus, Åbrink, Judy, Van de Water, Shirley, Luckhart
Publikováno v:
Frontiers in immunology. 13
An increase in mast cells (MCs) and MCs mediators has been observed in malaria-associated bacteremia, however, the role of these granulocytes in malarial immunity is poorly understood. Herein, we studied the role of mouse MC protease (Mcpt) 4, an ort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9f08e2e6a124f16724a962e35b92404
https://pubmed.ncbi.nlm.nih.gov/35154114
https://pubmed.ncbi.nlm.nih.gov/35154114
Autor:
Benjamin I, Laufer, Yu, Hasegawa, Zhichao, Zhang, Casey E, Hogrefe, Laura A, Del Rosso, Lori, Haapanen, Hyeyeon, Hwang, Melissa D, Bauman, Judy, Van de Water, Ameer Y, Taha, Carolyn M, Slupsky, Mari S, Golub, John P, Capitanio, Catherine A, VandeVoort, Cheryl K, Walker, Janine M, LaSalle
Publikováno v:
Nature communications. 13(1)
Maternal obesity during pregnancy is associated with neurodevelopmental disorder (NDD) risk. We utilized integrative multi-omics to examine maternal obesity effects on offspring neurodevelopment in rhesus macaques by comparison to lean controls and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ed889ca50953d58ceb2b547a6ddab3e
https://pubmed.ncbi.nlm.nih.gov/36130949
https://pubmed.ncbi.nlm.nih.gov/36130949
Autor:
John Paul Aboubechara, Iva Zdilar, Scott Cameron, Kartik Angara, Jin Myeong Seo, Deborah van der List, Daniel Vogt, Emma C Connolly, Linda Su-Feher, Lori Haapanen, Judy Van de Water, Cesar P Canales, Kathryn Prendergast, Tyler W. Stradleigh, Myka L. Estes, Jack B Goon, A. Kimberley McAllister, Karol Cichewicz, Kathleen Farrelly, Alexander Nord, Ellie J Kreun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b977b1b31e45987bed2858c9d608c81
https://doi.org/10.7554/elife.60100.sa2
https://doi.org/10.7554/elife.60100.sa2
Autor:
Lori Haapanen, Sarah M. Garrison, Erinn Donnelly, Judy Van de Water, Nora Céspedes, Shirley Luckhart
Publikováno v:
Infection and immunity, vol 88, iss 12
Infection and Immunity
Infection and Immunity
Malaria strongly predisposes to bacteremia, which is associated with sequestration of parasitized red blood cells and increased gastrointestinal permeability. The mechanisms underlying this disruption are poorly understood. Here, we evaluated the exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7e2a4870e1b61a0d4d738b1ed132b9
https://escholarship.org/uc/item/916909c5
https://escholarship.org/uc/item/916909c5
Autor:
Lori Haapanen, Danielle John Tan, Catherine T. Le, Kathleen Farrelly, Aurora Horta, Scott Cameron, Jeremy A. MacMahon, Joseph Schauer, Ida C. Shaffer, Deborah van der List, A. Kimberley McAllister, Kathryn Prendergast, Greg N. Kincheloe, Myka L. Estes, Gabrielle L. Sell, John Paul Aboubechara, Cameron S. Carter, Judy Van de Water, Melissa D. Bauman
Publikováno v:
Brain Behav Immun
Despite the potential of rodent models of maternal immune activation (MIA) to identify new biomarkers and therapeutic interventions for a range of psychiatric disorders, current approaches using these models ignore two of the most important aspects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2744d29cae61d7e7b52f25a46eb12eba
https://escholarship.org/uc/item/30g2k0gm
https://escholarship.org/uc/item/30g2k0gm