In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system

Autor: Lori Glenwinkel, Seth R Taylor, Kasper Langebeck-Jensen, Laura Pereira, Molly B Reilly, Manasa Basavaraju, Ibnul Rafi, Eviatar Yemini, Roger Pocock, Nenad Sestan, Marc Hammarlund, David M Miller III, Oliver Hobert

Publikováno v: eLife, Vol 10 (2021)

The generation of the enormous diversity of neuronal cell types in a differentiating nervous system entails the activation of neuron type-specific gene batteries. To examine the regulatory logic that controls the expression of neuron type-specific ge

Externí odkaz: https://doaj.org/article/af7e725ca0754a56a5647a1273beb41c

An atlas of Caenorhabditis elegans chemoreceptor expression.

Autor: Berta Vidal, Ulkar Aghayeva, Haosheng Sun, Chen Wang, Lori Glenwinkel, Emily A Bayer, Oliver Hobert

Publikováno v: PLoS Biology, Vol 16, Iss 1, p e2004218 (2018)

One goal of modern day neuroscience is the establishment of molecular maps that assign unique features to individual neuron types. Such maps provide important starting points for neuron classification, for functional analysis, and for developmental s

Externí odkaz: https://doaj.org/article/0b64594e61f84d8b8a8e7eaed4e67679

In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system

Autor: Marc Hammarlund, Laura Pereira, Molly B. Reilly, Nenad Sestan, Eviatar Yemini, Seth R. Taylor, Manasa Basavaraju, Lori Glenwinkel, Roger Pocock, Oliver Hobert, Ibnul Rafi, Kasper Langebeck-Jensen, David M. Miller

Publikováno v: eLife
Glenwinkel, L, Taylor, S R, Langebeck-Jensen, K, Pereira, L, Reilly, M B, Basavaraju, M, Rafi, I, Yemini, E, Pocock, R, Sestan, N, Hammarlund, M, Miller, D M & Hobert, O 2021, ' In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the c. Elegans nervous system ', eLife, vol. 10, e64906, pp. 1-29 . https://doi.org/10.7554/eLife.64906
eLife, Vol 10 (2021)

The generation of the enormous diversity of neuronal cell types in a differentiating nervous system entails the activation of neuron type-specific gene batteries. To examine the regulatory logic that controls the expression of neuron type-specific ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ada1d3f86da46d0b2b940e043a9073
http://europepmc.org/articles/PMC8225391

Author response: The Prop1-like homeobox gene unc-42 specifies the identity of synaptically connected neurons

Autor: Steven J. Cook, Yasmin H Ramadan, HaoSheng Sun, Emily Berghoff, Amelia Antone, Cyril Cros, David H. Hall, Oliver Hobert, Nicki Mohammadi, Neda Masoudi, Jordan F. Wood, Yi Feng, Erdem Varol, Abhishek Bhattacharya, Ken Nguyen, Lori Glenwinkel, Denise M. Ferkey

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d40a3f5400d6d3e6be2d2f6473b51cb6
https://doi.org/10.7554/elife.64903.sa2

Molecular topography of an entire nervous system

Autor: Alexander J. Abrams, Rebecca McWhirter, Alexis Weinreb, Seth R. Taylor, Panos Oikonomou, Nenad Sestan, Cyril Cros, Berta Vidal, Gabriel Santpere, Erdem Varol, Lori Glenwinkel, Saeed Tavazoie, Abigail Poff, Steven J. Cook, Alec Barrett, Marc Hammarlund, Manasa Basavaraju, Oliver Hobert, Eviatar Yemini, David M. Miller, Chuan Xu, Ibnul Rafi, Molly B. Reilly

Publikováno v: Cell

We have produced gene expression profiles of all 302 neurons of the C. elegans nervous system that match the single-cell resolution of its anatomy and wiring diagram. Our results suggest that individual neuron classes can be solely identified by comb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef652814b9048afd35c0ac71347d1754
https://pubmed.ncbi.nlm.nih.gov/34237253