Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Lori Coward"'
Autor:
Julia Tobacyk, Brian J. Parks, Lori Coward, Michael D. Berquist, Gregory S. Gorman, Lisa K. Brents
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 139-140 (2023)
OBJECTIVES/GOALS: Buprenorphine (BUP) is used for opioid use disorder during pregnancy but causes neonatal opioid withdrawal syndrome (NOWS). The goal of this study was to determine the contribution of the active metabolite, norbuprenorphine (NorBUP)
Externí odkaz:
https://doaj.org/article/5d3dca4f3b85413fb384145a37f29147
Autor:
Jimiece Thomas, Haddon Smith, C. Aaron Smith, Lori Coward, Gregory Gorman, Maria De Luca, Patricia Jumbo-Lucioni
Publikováno v:
Pathophysiology, Vol 28, Iss 2, Pp 307-319 (2021)
The use of angiotensin-converting enzyme inhibitors (ACEis) has been reported to reduce symptoms of cognitive decline in patients with Alzheimer’s disease (AD). Yet, the protective role of ACEis against AD symptoms is still controversial. Here, we
Externí odkaz:
https://doaj.org/article/484a9af10daa4d979d916ab5182e9d36
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 48:115-118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda0af4f194ecabd7e7c4559f16eb939
https://doi.org/10.1007/s13318-022-00801-9
https://doi.org/10.1007/s13318-022-00801-9
Autor:
Gary A. Piazza, Margie L. Clapper, Harry S. Cooper, Adam B. Keeton, Gang Zhou, Lori Coward, Greg Gorman, Elmar Nurmemmedov, Mary Pat Moyer, Yulia Maxuitenko, Kristy Berry, Ashley Nguyen, Ashleigh Neese, Charles Wood, Bing Zhu, Joel Andrews, Ashley S. Lindsey, Tyler Mattox, Antonio Ward, Silas J. Leavesley, Naga S. Annamdevula, Luciana Madeira da Silva, Alla Musiyenko, Elaine Gavin, Veronica Ramirez-Alcantara, Jacob Valiyaveettil, Xi Chen, Wen-Chi L. Chang, Kevin J. Lee
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd1f8dd00b73f74f39564ed161f568a
https://doi.org/10.1158/1940-6207.22533268
https://doi.org/10.1158/1940-6207.22533268
Autor:
Gary A. Piazza, Margie L. Clapper, Harry S. Cooper, Adam B. Keeton, Gang Zhou, Lori Coward, Greg Gorman, Elmar Nurmemmedov, Mary Pat Moyer, Yulia Maxuitenko, Kristy Berry, Ashley Nguyen, Ashleigh Neese, Charles Wood, Bing Zhu, Joel Andrews, Ashley S. Lindsey, Tyler Mattox, Antonio Ward, Silas J. Leavesley, Naga S. Annamdevula, Luciana Madeira da Silva, Alla Musiyenko, Elaine Gavin, Veronica Ramirez-Alcantara, Jacob Valiyaveettil, Xi Chen, Wen-Chi L. Chang, Kevin J. Lee
HPLC chromatogram of ADT 061
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b66933ddc1218fa7030aec152176d5c
https://doi.org/10.1158/1940-6207.22533286.v1
https://doi.org/10.1158/1940-6207.22533286.v1
Autor:
Gary A. Piazza, Margie L. Clapper, Harry S. Cooper, Adam B. Keeton, Gang Zhou, Lori Coward, Greg Gorman, Elmar Nurmemmedov, Mary Pat Moyer, Yulia Maxuitenko, Kristy Berry, Ashley Nguyen, Ashleigh Neese, Charles Wood, Bing Zhu, Joel Andrews, Ashley S. Lindsey, Tyler Mattox, Antonio Ward, Silas J. Leavesley, Naga S. Annamdevula, Luciana Madeira da Silva, Alla Musiyenko, Elaine Gavin, Veronica Ramirez-Alcantara, Jacob Valiyaveettil, Xi Chen, Wen-Chi L. Chang, Kevin J. Lee
HPLC chromatogram of compound 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07dbfc3c3f3c9bf58f3207098508123b
https://doi.org/10.1158/1940-6207.22533301.v1
https://doi.org/10.1158/1940-6207.22533301.v1
Autor:
Gary A. Piazza, Margie L. Clapper, Harry S. Cooper, Adam B. Keeton, Gang Zhou, Lori Coward, Greg Gorman, Elmar Nurmemmedov, Mary Pat Moyer, Yulia Maxuitenko, Kristy Berry, Ashley Nguyen, Ashleigh Neese, Charles Wood, Bing Zhu, Joel Andrews, Ashley S. Lindsey, Tyler Mattox, Antonio Ward, Silas J. Leavesley, Naga S. Annamdevula, Luciana Madeira da Silva, Alla Musiyenko, Elaine Gavin, Veronica Ramirez-Alcantara, Jacob Valiyaveettil, Xi Chen, Wen-Chi L. Chang, Kevin J. Lee
AST and ALT activity of male APC+/Min-FCCC mice administered varying doses of ADT 061 in the diet. Enzyme activity was measured in plasma samples. Results are presented as mean {plus minus} SEM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cd98d432962a31f53569fe3e05fb82
https://doi.org/10.1158/1940-6207.22533271
https://doi.org/10.1158/1940-6207.22533271
Autor:
Gary A. Piazza, Margie L. Clapper, Harry S. Cooper, Adam B. Keeton, Gang Zhou, Lori Coward, Greg Gorman, Elmar Nurmemmedov, Mary Pat Moyer, Yulia Maxuitenko, Kristy Berry, Ashley Nguyen, Ashleigh Neese, Charles Wood, Bing Zhu, Joel Andrews, Ashley S. Lindsey, Tyler Mattox, Antonio Ward, Silas J. Leavesley, Naga S. Annamdevula, Luciana Madeira da Silva, Alla Musiyenko, Elaine Gavin, Veronica Ramirez-Alcantara, Jacob Valiyaveettil, Xi Chen, Wen-Chi L. Chang, Kevin J. Lee
Reaction steps for synthesis of ADT 061 (a) 3-(4-methoxyphenyl)-2-methylacrylic acid (compound 1): 4-Methoxybenzaldehyde (219 g, 1.61 mole), propionic anhydride (315g, 2.42 mole), and sodium propionate (155g, 1.61 mole) were stirred at 140 ºC unti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd02d02bcdfbad1ca60d30e0de1f76d
https://doi.org/10.1158/1940-6207.22533310
https://doi.org/10.1158/1940-6207.22533310
Autor:
Gary A. Piazza, Margie L. Clapper, Harry S. Cooper, Adam B. Keeton, Gang Zhou, Lori Coward, Greg Gorman, Elmar Nurmemmedov, Mary Pat Moyer, Yulia Maxuitenko, Kristy Berry, Ashley Nguyen, Ashleigh Neese, Charles Wood, Bing Zhu, Joel Andrews, Ashley S. Lindsey, Tyler Mattox, Antonio Ward, Silas J. Leavesley, Naga S. Annamdevula, Luciana Madeira da Silva, Alla Musiyenko, Elaine Gavin, Veronica Ramirez-Alcantara, Jacob Valiyaveettil, Xi Chen, Wen-Chi L. Chang, Kevin J. Lee
Mass spectroscopy of compound 5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c1b9ab47b1ad6c6194c30774cc23c8
https://doi.org/10.1158/1940-6207.22533298
https://doi.org/10.1158/1940-6207.22533298
Autor:
Gary A. Piazza, Margie L. Clapper, Harry S. Cooper, Adam B. Keeton, Gang Zhou, Lori Coward, Greg Gorman, Elmar Nurmemmedov, Mary Pat Moyer, Yulia Maxuitenko, Kristy Berry, Ashley Nguyen, Ashleigh Neese, Charles Wood, Bing Zhu, Joel Andrews, Ashley S. Lindsey, Tyler Mattox, Antonio Ward, Silas J. Leavesley, Naga S. Annamdevula, Luciana Madeira da Silva, Alla Musiyenko, Elaine Gavin, Veronica Ramirez-Alcantara, Jacob Valiyaveettil, Xi Chen, Wen-Chi L. Chang, Kevin J. Lee
ADT 061 pharmacokinetics and tissue distribution. ADT 061 was detected in plasma at a concentration of 2.8 µM 0.5 hr after a single oral administration of a dose of 100 mg/kg in 0.5% CMC/0.25% T80 in water to female C57BL/6 mice and reached plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c071102f503fd37a06478fea5a9053
https://doi.org/10.1158/1940-6207.22533274
https://doi.org/10.1158/1940-6207.22533274