Výsledky vyhledávání

Understanding Treatment Burden and Quality of Life Impact of Participating in an Early-Phase Pediatric Oncology Clinical Trial: A Pilot Study

Autor: Stacey Crane, Janet S. Carpenter, Joan E. Haase, Beth Stockman, Lori Backus, Li Lin

Publikováno v: Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses. 35(1)

Purpose: Early-phase clinical trials (EPTs) have led to new, more effective treatment options for children with cancer. Despite the extensive use of EPTs in pediatric oncology, little is known about parent and child experiences during EPT participati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20cb0d4605ee961d7778ea81157f9f7
https://pubmed.ncbi.nlm.nih.gov/28849701

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Intratumoral Injection of HSV1716, an Oncolytic Herpes Virus, Is Safe and Shows Evidence of Immune Response and Viral Replication in Young Cancer Patients

Autor: Kristy Ott-Napier, Kathleen Simpson, Michele R. Vaughan, Lori Backus, John M. Racadio, Patrick Warren, Robert Spavin, Devon J. Dishman, Beth Stockman, James I. Geller, Joe Conner, Keri A. Streby, Marianne M Brunner, Alexander J. Towbin, Mark A. Currier, Timothy P. Cripe, Melinda Triplet

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 23(14)

Purpose: HSV1716 is an oncolytic herpes simplex virus-1 (HSV-1) studied in adults via injection into the brain and superficial tumors. To determine the safety of administering HSV1716 to pediatric patients with cancer, we conducted a phase I trial of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdea6ef492420a537b187e746a18e49
https://pubmed.ncbi.nlm.nih.gov/28495911

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A pilot study of bevacizumab-based therapy in patients with newly diagnosed high-grade gliomas and diffuse intrinsic pontine gliomas

Autor: James L. Leach, David W. Pruitt, Mary Sutton, Lori Backus, Charles B. Stevenson, Ahna L. H. Pai, Stewart Goldman, Adam Lane, Maryam Fouladi, Trent R. Hummel, Renee Doughman, Rachid Drissi, Ralph Salloum, Mariko DeWire, Matthew Sobo, Shiva Senthil Kumar, Lionel M.L. Chow, Lili Miles, Laurie Grimme

Publikováno v: Journal of neuro-oncology. 127(1)

Although bevacizumab has not proven effective in adults with newly diagnosed high-grade gliomas (HGG), feasibility in newly diagnosed children with diffuse intrinsic pontine gliomas (DIPG) or HGG has not been reported in a prospective study. In a saf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bcbbe8d410e94a6d5be200d10585f3
https://pubmed.ncbi.nlm.nih.gov/26626490

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