Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lori B. Hays"'
Publikováno v:
BioTechniques, Vol 29, Iss 2, Pp 288-296 (2000)
The yeast two-hybrid system has been used to characterize many protein-protein interactions. A two-hybrid system for E. coli was constructed in which one hybrid protein bound to a specific DNA site recruits another to an adjacent DNA binding site. Th
Externí odkaz:
https://doaj.org/article/6919808f194842959bdbc90b62883007
Publikováno v:
Journal of Biological Chemistry. 280:32413-32418
Abnormalities in lipid metabolism have been proposed as contributing factors to both defective insulin secretion from the pancreatic beta cell and peripheral insulin resistance in type 2 diabetes. Previously, we have shown that prolonged exposure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8551f14fe7928f4fd9e6ad71aad0cfc7
https://doi.org/10.1074/jbc.m506000200
https://doi.org/10.1074/jbc.m506000200
Autor:
Scott T. Brady, Scott Sommers, Christopher J. Rhodes, Richard Julyan, Jeffery D. Molkentin, Matthew J. Donelan, Isabelle Briaud, Lori B. Hays, Gerardo Morfini, Richard A. Easom, Hiroshi Kajio
Publikováno v:
Journal of Biological Chemistry. 277:24232-24242
The specific biochemical steps required for glucose-regulated insulin exocytosis from beta-cells are not well defined. Elevation of glucose leads to increases in cytosolic [Ca2+]i and biphasic release of insulin from both a readily releasable and a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4fe5aa76f238019144c4be3412cf588
https://doi.org/10.1074/jbc.m203345200
https://doi.org/10.1074/jbc.m203345200
Publikováno v:
BioTechniques. 29:288-296
The yeast two-hybrid system has been used to characterize many protein-protein interactions. A two-hybrid system for E. coli was constructed in which one hybrid protein bound to a specific DNA site recruits another to an adjacent DNA binding site. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86f55c5496c48bc41ecfd5848db76665
https://doi.org/10.2144/00292st04
https://doi.org/10.2144/00292st04
Syncollin is a 13 kDa protein that is highly expressed in the exocrine pancreas. Syncollin normally exists as a doughnut-shaped homo-oligomer (quite probably a hexamer) in close association with the luminal surface of the zymogen granule membrane. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb84bfe37052234f549905981a90ea8c
https://europepmc.org/articles/PMC1224234/
https://europepmc.org/articles/PMC1224234/
Autor:
Richard Julyan, Kazuro Yaekura, Yong Wang, Louis H. Philipson, Denis G. Baskin, Lori B. Hays, Barton Luke Wicksteed, Scott Sommers, Vincent Poitout, Cristina Alarcon, Christopher J. Rhodes
Publikováno v:
The Journal of biological chemistry. 278(11)
Insulin secretory dysfunction of the pancreatic beta-cell in type-2 diabetes is thought to be due to defective nutrient sensing and/or deficiencies in the mechanism of insulin exocytosis. Previous studies have indicated that the GTP-binding protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5aa746e9eae78b7e77fd242235308e
https://pubmed.ncbi.nlm.nih.gov/12510060
https://pubmed.ncbi.nlm.nih.gov/12510060