Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lori An Etherington"'
Autor:
Michael Spedding, Claude Sebban, Thérèse M. Jay, Cyril Rocher, Brigitte Tesolin-Decros, Paul Chazot, Esther Schenker, Gabor Szénási, György I. Lévay, Katalin Megyeri, Jozsef Barkóczy, Laszlo G. Hársing, Ian Thomson, Mark O. Cunningham, Miles A. Whittington, Lori-An Etherington, Jeremy J. Lambert, Ferenc A. Antoni, Istvan Gacsályi
Publikováno v:
Cells, Vol 11, Iss 7, p 1181 (2022)
Dysfunction in the hippocampus-prefrontal cortex (H-PFC) circuit is a critical determinant of schizophrenia. Screening of pyridazinone-risperidone hybrids on this circuit revealed EGIS 11150 (S 36549). EGIS 11150 induced theta rhythm in hippocampal s
Externí odkaz:
https://doaj.org/article/a9ff5b5911fe463bbd0919d101083673
Publikováno v:
Current topics in behavioral neurosciences. 49
Although there are effective treatments available for many, probably most, patients with OCD, a significant number do not respond, or fail to experience a sustained beneficial response. For patients with such chronic, disabling and 'treatment-refract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ab48c1041a392f0125fa00e5e6275b2
https://pubmed.ncbi.nlm.nih.gov/33565041
https://pubmed.ncbi.nlm.nih.gov/33565041
Autor:
Lori-An Etherington, Adrienn Pálvölgyi, Katalin Pallagi, Ferenc A. Antoni, Adam R. Brown, József Barkóczy, Delia Belelli, Olivia Monteiro, Szabolcs Kertesz, Ben G. Gunn, Michael Spedding, Balázs Mihalik, Istvan Gacsalyi, István Ling, Matthew R. Livesey, Péter Varga, Jeremy J. Lambert
Publikováno v:
Etherington, L-A, Mihalik, B, Pálvölgyi, A, Ling, I, Pallagi, K, Kertész, S, Varga, P, Gunn, B, Brown, A, Livesey, M, Monteiro, O, Belelli, D, Barkóczy, J, Spedding, M, Gacsályi, I, Antoni, F & Lambert, J 2017, ' Selective inhibition of extra-synaptic α5-GABAA receptors by S44819, a new therapeutic agent. ', Neuropharmacology, pp. 30379-9 . https://doi.org/10.1016/j.neuropharm.2017.08.012
In the mammalian central nervous system (CNS) GABAA receptors (GABAARs) mediate neuronal inhibition and are important therapeutic targets. GABAARs are composed of 5 subunits, drawn from 19 proteins, underpinning expression of 20–30 GABAAR subtypes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42c09c14917f391a41a6b52b26e2be7
https://doi.org/10.1016/j.neuropharm.2017.08.012
https://doi.org/10.1016/j.neuropharm.2017.08.012
Autor:
Gyula Simig, Adrienn Pálvölgyi, Szabolcs Kertesz, István Ling, Istvan Gacsalyi, Éva Szabó, Attila Gaál, Michael Spedding, Balázs Mihalik, Gábor Szénási, Delia Belelli, Gabor Gigler, Jeremy J. Lambert, Péter Kiricsi, Lori An Etherington, Balázs Volk, József Barkóczy, Katalin Pallagi, Ferenc A. Antoni, György Lévay, Gábor Kapus, Lilla Papp, Laszlo G. Harsing
Publikováno v:
European Journal of Pharmacology. 764:497-507
Novel 2,3-benzodiazepine and related isoquinoline derivatives, substituted at position 1 with a 2-benzothiophenyl moiety, were synthesized to produce compounds that potently inhibited the action of GABA on heterologously expressed GABAA receptors con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b449a320bd028d64481cb4dcfd24adf2
https://doi.org/10.1016/j.ejphar.2015.07.005
https://doi.org/10.1016/j.ejphar.2015.07.005
Autor:
Alexandra M. Z. Slawin, Fatima Chorki, Lori-An Etherington, Keith T. Sillar, Issberner J, Gildas Deniau, Judith M. Heygate, David O'Hagan, Tanja van Mourik, Tomas Lebl, Jeremy J. Lambert
Publikováno v:
ChemBioChem. 8:2265-2274
Gamma-aminobutyric acid or GABA (1) is one of the major inhibitory amino acid neurotransmitters of the central nervous system. This article describes the first synthesis of both the (R)- and (S)- enantiomers of 3-fluoro-GABA (2, 3F-GABA). DFT calcula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c82783cc55fe78565380748893c4b2
https://doi.org/10.1002/cbic.200700371
https://doi.org/10.1002/cbic.200700371