Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lori A. Zupan"'
Autor:
Barry L. Parnas, Randy H. Weiss, Richard W. Gross, Stanley L. Hazen, Daniel P. Getman, Karl W. Aston, Patrick J. Lennon, Lori A. Zupan
Publikováno v:
Journal of Medicinal Chemistry. 36:95-100
Haloenol lactones are potent mechanism-based inhibitors of a novel class of calcium-independent phospholipases A2 which have been implicated as the enzymic mediators of membrane dysfunction during myocardial ischemia (Hazen, S. L.; et al. J. Biol. Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e397d9026a25039dc79e818e404d01aa
https://doi.org/10.1021/jm00053a012
https://doi.org/10.1021/jm00053a012
Publikováno v:
Journal of Biological Chemistry. 267:8707-8710
The major phospholipase A2 activity in sheep platelets is mediated by at least three chromatographically resolvable isoforms of a 30-kDa dimeric polypeptide which are responsive to physiologic increments in calcium ion and possess a dramatic substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::675c2441756ba5a4fbc12d041f67e358
https://doi.org/10.1016/s0021-9258(19)50334-9
https://doi.org/10.1016/s0021-9258(19)50334-9
Publikováno v:
Journal of Biological Chemistry. 266:7227-7232
The majority of phospholipase A2 activity in myocardium is calcium-independent and selective for hydrolysis of plasmalogen substrate (Wolf, R. A., and Gross, R. W. (1985) J. Biol. Chem. 260, 7295-7303; Hazen, S. L., Stuppy, R. J., and Gross, R. W. (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4353e78b824f7fc2ea7ea169cfab9c89
https://doi.org/10.1016/s0021-9258(20)89634-3
https://doi.org/10.1016/s0021-9258(20)89634-3
Publikováno v:
Analytical biochemistry. 200(1)
Methods for the efficient use of limiting amounts of fatty acid probes in the synthesis of individual molecular species of plasmenylcholine have been developed. Plasmenylcholine molecular species were synthesized through acylation of homogeneous 1- O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b3578dd1459488d12079d0dc643fec
https://pubmed.ncbi.nlm.nih.gov/1317681
https://pubmed.ncbi.nlm.nih.gov/1317681
Publikováno v:
FEBS Letters. (1):27-30
In this study we demonstrate that: (1) although the major phospholipase A2 present in sheep platelets is activated by calcium ions, it can effectively catalyze hydrolysis of the sn-2 ester linkage in phospholipids in the absence of calcium: (2) expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d15415142d3d4be51f080c168dd139e