Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lori A. Fischer"'
Publikováno v:
Frontiers in Oral Health, Vol 5 (2024)
In a murine model (LCΔMHC-II) designed to abolish MHC-II expression in Langerhans cells (LCs), ∼18% of oral LCs retain MHC-II, yet oral mucosal CD4 T cells numbers are unaffected. In LCΔMHC-II mice, we now show that oral intraepithelial conventio
Externí odkaz:
https://doaj.org/article/0ac138362d3f4eb893dfcd4fc8a5dd38
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In periodontitis Porphyromonas gingivalis contributes to the development of a dysbiotic oral microbiome. This altered ecosystem elicits a diverse innate and adaptive immune response that simultaneously involves Th1, Th17, and Treg cells. It has been
Externí odkaz:
https://doaj.org/article/a9da6bff21ed436e9ff82d9811be912b
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mouse models that combine specific loxP-flanked gene sequences with Cre recombinase expressed from cell-regulated promoters have become important tools to investigate gene function. Critically however, expression of Cre recombinase may not always be
Externí odkaz:
https://doaj.org/article/12b4b56dd9cf4ae98891b6c8018667c1
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Periodontitis is a chronic inflammatory response to a microbial biofilm that destroys bone and soft tissues supporting the teeth. Murine models of periodontitis based on Porphyromonas gingivalis (Pg) colonization have shown that extravasation of leuk
Externí odkaz:
https://doaj.org/article/c744e0387b6c41cea4e1a20b70983e07
Publikováno v:
Frontiers in Immunology
In periodontitis Porphyromonas gingivalis contributes to the development of a dysbiotic oral microbiome. This altered ecosystem elicits a diverse innate and adaptive immune response that simultaneously involves Th1, Th17, and Treg cells. It has been
Publikováno v:
Infection and Immunity. 87
Porphyromonas gingivalis is considered a keystone pathogen that contributes to the initiation and progression of periodontitis in humans. P. gingivalis has also been detected in human placentas associated with adverse pregnancy outcomes. The spread o
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Mouse models that combine specific loxP-flanked gene sequences with Cre recombinase expressed from cell-regulated promoters have become important tools to investigate gene function. Critically however, expression of Cre recombinase may not always be
Observational studies demonstrate that women with severe periodontitis have a higher risk of adverse pregnancy outcomes like preterm birth and low birthweight. Standard treatment for periodontitis in the form of scaling and root planing during the se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab060eec44a6dfabb301563d16bd7a1
https://europepmc.org/articles/PMC6821581/
https://europepmc.org/articles/PMC6821581/
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in Immunology
Periodontitis is a chronic inflammatory response to a microbial biofilm that destroys bone and soft tissues supporting the teeth. Murine models of periodontitis based on Porphyromonas gingivalis (Pg) colonization have shown that extravasation of leuk
Publikováno v:
Molecular Oral Microbiology. 28:452-466
Chronic periodontitis is associated with Porphyromonas gingivalis infection. Although virulence factors of P. gingivalis are hypothesized to contribute to the pathogenesis of periodontitis, it is unclear whether the local CD4(+) T-cell-mediated respo