Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Lori A, Plum"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The vitamin D receptor as well as its ligand have been localized to various immune tissues and cells. These observations have led researchers to hypothesize a role for vitamin D in the immune system. However, a specific role for vitamin D in immunity
Externí odkaz:
https://doaj.org/article/f55e256f4ee24cf992e9492407cc8ca9
Publikováno v:
Biology Open, Vol 11, Iss 7 (2022)
Epidemiological observations have prompted some to posit that elevated circulating vitamin D is responsible for reduced colon cancer in individuals residing near the equator. We have previously demonstrated that vitamin D has no effect on colon cance
Externí odkaz:
https://doaj.org/article/2c4c55a805204ebda4a25675ba1b66d4
Publikováno v:
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Abstract Vitamin D3 is a prohormone that is essential for calcium homeostasis. It is naturally produced in the skin by ultraviolet‐B (UVB) irradiation of 7‐dehydrocholesterol. In the absence of skin production, vitamin D3 can also be obtained fro
Externí odkaz:
https://doaj.org/article/78f4facfedca4bf5bf8c540dc872eb25
Publikováno v:
Photochemical & Photobiological Sciences. 21:1399-1404
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 3 (2018)
Human studies have shown that individuals with colon cancer tend to have lower serum 25-hydroxy-vitamin D3 [25(OH)D3] levels compared with healthy controls, but whether this link is causative, a result of the disease or an indicator of another factor
Externí odkaz:
https://doaj.org/article/b6c45e89a8964e6195b9abc729ae26a2
Autor:
Mark B. Meyer, Carlos Bernal-Mizrachi, Daniel D. Bikle, Madhu Biyani, Moray J. Campbell, Snehal N. Chaudhari, Sylvia Christakos, Sue A. Ingles, Megan M. Knuth, Seong Min Lee, Thomas S. Lisse, Eva S. Liu, Isabelle Piec, Lori A. Plum, Sudhaker D. Rao, Carmen J. Reynolds, Tom D. Thacher, John H. White, Margherita T. Cantorna
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 228:106247
Publikováno v:
Photochemicalphotobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 21(8)
The primary source of vitamin D3 for humans is that produced in skin by ultraviolet irradiation. Ultraviolet (UV) B (UVB, 280-310 nm) light causes the isomerization of 7-dehydrocholesterol (7-DHC) to pre-vitamin D3 that is thermally isomerized to vit
Autor:
Adrian Fabisiak, Hector F. DeLuca, Pawel Brzeminski, Izabela K. Sibilska-Kaminski, Lori A. Plum, Rafal R. Sicinski
Publikováno v:
Bioorganic chemistry. 118
A new series of highly biologically active (20S,22R)-1α,25-dihydroxy-22-methyl- 2-methylene-vitamin D3 analogs, possessing different side chains, have been efficiently prepared as potential agents for medical therapy. Design of these synthetic targe
Publikováno v:
Proc Natl Acad Sci U S A
Vitamin D is produced in the skin following exposure to sunlight. Ultraviolet (UV) B (UVB, 280–310 nm) results in isomerization of 7-dehydrocholesterol to previtamin D that spontaneously isomerizes to vitamin D. This pool of skin-derived vitamin D