Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lori, Kornberg"'
Autor:
Sabine Ermisch, Ting Wang, Michael A. Carducci, Jeannette Day, Deborah K. Armstrong, Lori Kornberg, Rodney Decker, Connie Collins, Steven J. Nicol, Donald Thornton, Lee P. Resta, Zhe Zhang, Nwabundo Nwankwo
Publikováno v:
Investigational New Drugs
Summary Purpose Given distinct mechanism of actions of enzastaurin and bevacizumab, preclinical studies suggest enhanced antitumor activity in combination. This phase I study assessed the combination’s safety and efficacy. Patients and methods Six
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472eebf5ca200034f61e7d9df3fcb0b9
https://doi.org/10.1007/s10637-012-9850-6
https://doi.org/10.1007/s10637-012-9850-6
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1242:77-98
Over the last few years, it has become clear that cell adhesion receptors function in signal transduction processes leading to the regulation of cell growth and differentiation. Signal transduction by both integrins and CAMs has been shown to involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f251de4cebfeadb7c86b22b18fb4ffca
https://doi.org/10.1016/0304-419x(95)00005-z
https://doi.org/10.1016/0304-419x(95)00005-z
Autor:
Lori Kornberg, J. S. Bauer, Judy A. Varner, Clara Schreiner, Rudy L. Juliano, Robert A. Nicholas
Publikováno v:
The Journal of Cell Biology
The purpose of this study was to explore the functional role of the cytoplasmic domain of the alpha subunit of the alpha 5/beta 1 integrin, a fibronectin receptor. Mutant CHO cells that express very low levels of endogenous hamster alpha 5 subunit (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebca95b5123f8264ff0bbae269776e0
http://europepmc.org/articles/PMC2119610
http://europepmc.org/articles/PMC2119610
Autor:
Lori, Kornberg
Publikováno v:
Anticancer research. 26(4B)
Transformed cells have abnormalities in the survival pathways contributing to drug resistance. These abnormalities include p53 mutations and increased focal adhesion kinase (FAK) expression. Because FAK regulates cell survival via p53-dependent and -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::356515e1de6469770b1bc99b48c2b407
https://pubmed.ncbi.nlm.nih.gov/16886630
https://pubmed.ncbi.nlm.nih.gov/16886630
Autor:
Lori, Kornberg, Jeffery, Fleigel
Publikováno v:
Anticancer research. 23(1A)
Focal adhesion kinase (FAK), which has received much attention as a transducer of integrin-mediated signals, is overexpressed in several types of human cancer. FAK-related non-kinase (FRNK) is an autonomously expressed carboxyl-terminal region of FAK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fddec75bb1536962dcc77f17745673b3
https://pubmed.ncbi.nlm.nih.gov/12680199
https://pubmed.ncbi.nlm.nih.gov/12680199
Autor:
Nasser, Chegini, Lori, Kornberg
Publikováno v:
Journal of the Society for Gynecologic Investigation. 10(1)
Because gonadotropin releasing hormone analogue (GnRHa) therapy often causes leiomyoma regression, in part through alteration of growth factor and receptor expression, we determined whether GnRHa therapy alters the expression of extracellular signal-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63ec02cdbd502d95c6eaacf9b53083dc
https://pubmed.ncbi.nlm.nih.gov/12517589
https://pubmed.ncbi.nlm.nih.gov/12517589
Autor:
A. D. Kinghorn, Lori Kornberg, T E Chagwedera, Mansukh C. Wani, Fekadu Fullas, Norman R. Farnsworth, Monroe E. Wall
Publikováno v:
Journal of natural products. 59(2)
The rootwood of Aeschynomene mimosifolia Vatke (Leguminosae) has yielded a new neoflavonoid, mimosifoliol (1), and an unusual C16-styrylcycloheptenone derivative, mimosifolenone (2). The structures of these compounds were determined on the basis of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5383f208bd1ed19e26014d82bdd1b5
https://pubmed.ncbi.nlm.nih.gov/8991952
https://pubmed.ncbi.nlm.nih.gov/8991952
Autor:
Sarah Glover, Melissa Delaney, Cecile Dematte, Lori Kornberg, Melissa Frasco, Roger Tran-Son-Tay
Publikováno v:
Journal of Cellular Physiology; Apr2004, Vol. 199 Issue 1, p77-88, 12p