Zobrazeno 1 - 10
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pro vyhledávání: '"Lorglumide"'
Akademický článek
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Autor:
Hayato Koizumi, Kiyokazu Muto, Takatoshi Mochizuki, Eri Morioka, Weihong Pan, Nanami Matsuba, Juhyon Kim, Tomoya Ozaki, Shahid Mohammad, Masayuki Ikeda
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Cholecystokinin (CCK) and leptin are satiety-controlling peptides, yet their interactive roles remain unclear. Here, we addressed this issue using in vitro and in vivo models. In rat C6 glioma cells, leptin pre-treatment enhanced Ca2+ mobilization by
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 98:282-295
Apelin is a peptide that plays a role in physiological processes such as angiogenesis, apoptosis, and proliferation. The aim of this study was to investigate the role of capsaicin-sensitive afferent neurons and vagus in the effect of apelin against i
Publikováno v:
Aging (Albany NY)
To understand the changes in physiological responses due to aging, a number of bioactive probes based on different signal transduction pathways are necessary. In this study, we comprehensively and systematically investigated changes in blood vessel f
Autor:
Bin Wang, Yuanbing Wu, Shuyao Wang, Ni Tang, Xin Zhang, Zhiqiong Li, Jinwen Qi, Hu Chen, Zhengzhi Tian, Defang Chen, Jin Hao
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
To explore the effect of CCK on food intake in Siberian sturgeon, cck cDNA sequence of 1005 bp was obtained, and cck mRNA possessed the highest expression in brain. The expressions of cck were significantly increased after feeding 1 and 3 h, while di
Autor:
Mei Wang, Shuyao Wang, Shaoqi Xu, Xin Zhang, Zhiqiong Li, Yuanbing Wu, Jinwen Qi, Hu Chen, Bin Wang, Zhengzhi Tian, Defang Chen, Ni Tang
Publikováno v:
Comparative biochemistry and physiology. Part A, Molecularintegrative physiology. 234
Urocortin-3 (UCN3) as a brain-gut peptide inhibits food intake of animal, but the underlying mechanism is not clear. To explore the appetite mechanism about the action of UCN3 in fish, intraperitoneal injection of UCN3 with CCK8, Lorglumide (CCK1R an
Autor:
Paulus S. Wang, Chii-Min Hwu, Shih-Han Su, Ting-Chun Weng, Jou-Chun Chou, Jiun-Yih Yeh, Yu-Chung Chiao, An-Hsiang Chang, Ho Lin
Publikováno v:
Adaptive Medicine. 8:112-118
Dexamethasone is a potent glucocorticoid, which has been used in the anti-inflammation therapy. It has been well known that the gastrointestinal (GI) motility is affected by stress. However, the role of glucocorticoids in regulating GI motility is un
Publikováno v:
Adaptive Medicine. 8:40-44
It has been shown that gastric emptying is delayed in stressed animals. This investigation was to study the effect of adrenocorticotropin (ACTH), a stress hormone, on the gastric emptying and intestinal transit in rats. Fasted male rats were injected
Autor:
Yuanbing Wu, Xin Zhang, Shuyao Wang, Bin Wang, Hu Chen, Jinwen Qi, Defang Chen, Zhengzhi Tian, Ni Tang, Zhiqiong Li
Publikováno v:
Peptides. 109
Nesfatin-1 is an 82-amino acid protein derived from nucleobindin 2 (NUCB2), which could inhibit food intake in fish and mammals. However, the neuroendocrine mechanism of nesfatin-1 in animal appetite regulation is unclear. To explore the feeding mech
Publikováno v:
Journal of neuroendocrinology. 30(9)
Exposure to an acute stressor induces up-regulation of apelin and cholecystokinin (CCK) in the hypothalamic paraventricular nucleus (PVN), which is the key brain centre integrating the stress-induced alterations in neuroendocrine, autonomic and behav