Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Loretta M. Atkins"'
Autor:
Alayne B. Smith, Gale Gr, Lynda Beth Milligan, Mark A. Basinger, Loretta M. Atkins, Angie Stone, Mark M. Jones, Pramod K. Singh, Walker Em
Publikováno v:
Toxicology. 76:79-87
The following six monoalkyl esters of meso -2,3-dimercaptosuccinic acid (DMSA) were synthesized and evaluated for relative activities in mobilizing lead from kidneys and brains of lead-bearing mice: n -propyl (M n -PDMS), i -propyl (M i -PDMS), n -bu
Publikováno v:
Pharmacology & Toxicology. 70:336-343
The relative activities of a series of nine monoalkyl esters of meso-2,3-dimercaptosuccinic acid have been examined as agents for the mobilization of cadmium from mice one week after intraperitoneal administration of cadmium chloride. Eight of these
Autor:
Loretta M. Atkins, Shirley G. Jones, Mark M. Jones, James A. Banton, Glen R. Gale, Pramod K. Singh, Chetan R. Mukundan, Alayne B. Smith
Publikováno v:
Chemical Research in Toxicology. 4:27-34
The effects of three major structural features on the intracellular cadmium mobilizing potency of dithiocarbamates have been examined. These features, the chirality of the groups, the total ionic charge of the chelating agent, and the extent of chain
Publikováno v:
Toxicology and Applied Pharmacology. 106:529-535
The cadmium mobilizing properties of two newly synthesized esters of meso-2,3-dimercaptosuccinic acid in mice have been examined. They are: di(2'-methoxyethyl) meso-2,3-dimercaptosuccinate ([-CH(SH)COOCH2CH2OR]2, R = CH3; MEDMS), and di(2'-ethoxyethy
Publikováno v:
Toxicology Letters. 50:85-96
A number of dosing regimens was assessed to determine the optimum schedule of administration of N -(4-methoxybenzyl)- N -dithiocarboxy- d -glucamine (MeOBDCG) in depleting whole-body, renal and hepatic levels of metallothionein-bound cadmium (Cd) in
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 12(1)
The vitamin D receptor (VDR) binds to the vitamin D response element (VDRE) and mediates the effects of the biologically active form of vitamin D, 1,25-dihydroxyvitamin D3[ 1,25-(OH)2D3], on gene expression. The VDR binds to the VDRE as a heterodimer
Autor:
Glen R. Gale, Mark M. Jones, Loretta M. Atkins, Alayne B. Smith, Mark A. Basinger, Angie Stone
Publikováno v:
Toxicology. 89(2)
The effects of chelating agent treatment with meso-2,3-dimercaptosuccinic acid (DMSA), Na2CaEDTA, Na2ZnEDTA, and Na3ZnDTPA on the organ lead levels of lead-loaded mice have been determined. At 1 mmol/kg/day i.p., all caused reductions in the lead lev
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 17(3)
A serial prospective survey of nasal colonization of hospital personnel by methicillin-resistant coagulase-negative staphylococci (MRCNS) was conducted at a Veterans Affairs medical center on three occasions over a 16-month period. The epidemiologica
Publikováno v:
Diagnostic microbiology and infectious disease. 16(1)
From 1978 to 1988 strains of gentamicin-susceptible (Gm s ) and gentamicin-resistant (Gm r ) Klebsiella pneumoniae were saved from annual surveillance cultures of the perineal region of patients with spinal cord injury (SCI). Of 38 strains selected f
Publikováno v:
The Pediatric infectious disease journal. 11(11)
The emergence of methicillin-resistant coagulase-negative Staphylococcus as a major bacterial pathogen in neonatal intensive care units has stimulated interest in the epidemiology of spread of the organism. During a 12-month "epidemic" of bacteremias