Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Loretta De Chiara"'
Autor:
María Gallardo-Gómez, Mar Rodríguez-Girondo, Núria Planell, Sebastian Moran, Luis Bujanda, Ane Etxart, Antoni Castells, Francesc Balaguer, Rodrigo Jover, Manel Esteller, Joaquín Cubiella, David Gómez-Cabrero, Loretta De Chiara
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-17 (2023)
Abstract Background Early detection has proven to be the most effective strategy to reduce the incidence and mortality of colorectal cancer (CRC). Nevertheless, most current screening programs suffer from low participation rates. A blood test may imp
Externí odkaz:
https://doaj.org/article/30aa5504516a4b318ec2757d888d1389
Autor:
Hortensia Álvarez, Ezequiel Ruiz-Mateos, Pedro Miguel Juiz-González, Joana Vitallé, Irene Viéitez, María del Carmen Vázquez-Friol, Isabel Torres-Beceiro, Alberto Pérez-Gómez, Pilar Gallego-García, Nuria Estévez-Gómez, Loretta De Chiara, Eva Poveda, David Posada, Josep M. Llibre
Publikováno v:
Microorganisms, Vol 10, Iss 1, p 143 (2022)
Intra-host evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported in cases with persistent coronavirus disease 2019 (COVID-19). In this study, we describe a severely immunosuppressed individual with HIV-1/SARS-CoV
Externí odkaz:
https://doaj.org/article/c25d134b4c77454eb84f78708944c8ec
Autor:
María Gallardo-Gómez, Sebastian Moran, María Páez de la Cadena, Vicenta Soledad Martínez-Zorzano, Francisco Javier Rodríguez-Berrocal, Mar Rodríguez-Girondo, Manel Esteller, Joaquín Cubiella, Luis Bujanda, Antoni Castells, Francesc Balaguer, Rodrigo Jover, Loretta De Chiara
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Colorectal cancer is the fourth cause of cancer-related deaths worldwide, though detection at early stages associates with good prognosis. Thus, there is a clear demand for novel non-invasive tests for the early detection of color
Externí odkaz:
https://doaj.org/article/91b0328e34974e03be11e529d81848f6
Autor:
Sonia Blanco-Prieto, Leticia Barcia-Castro, María Páez de la Cadena, Francisco Javier Rodríguez-Berrocal, Lorena Vázquez-Iglesias, María Isabel Botana-Rial, Alberto Fernández-Villar, Loretta De Chiara
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background The need for novel biomarkers that could aid in non-small cell lung cancer (NSCLC) detection, together with the relevance of Matrix Metalloproteases (MMPs) -1, -2, -7, -9 and -10 in lung tumorigenesis, prompted us to assess the di
Externí odkaz:
https://doaj.org/article/90e78769100f4e03ab8e6fb85e4ca699
Autor:
Eduarda Carvalho-Correia, Carla Calçada, Fernando Branca, Nuria Estévez-Gómez, Loretta De Chiara, Nair Varela, Pilar Gallego-García, David Posada, Hugo Sousa, João Sousa, Maria Isabel Veiga, Nuno S. Osório
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1314 (2021)
Extensive transmission of SARS-CoV-2 during the COVID-19 pandemic allowed the generation of thousands of mutations within its genome. While several of these become rare, others largely increase in prevalence, potentially jeopardizing the sensitivity
Externí odkaz:
https://doaj.org/article/ba1274f15f594a098ad9311c519c297d
Autor:
Loretta De Chiara, Virginia Leiro-Fernandez, Mar Rodríguez-Girondo, Diana Valverde, María Isabel Botana-Rial, Alberto Fernández-Villar
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 9242 (2020)
Different methodological approaches are available to assess DNA methylation biomarkers. In this study, we evaluated two sodium bisulfite conversion-dependent methods, namely pyrosequencing and methylation-specific qPCR (MS-qPCR), with the aim of meas
Externí odkaz:
https://doaj.org/article/ec2ba2cabbaf47fa9f4a3137f963df0e
Autor:
Olalla Otero-Estévez, María Gallardo-Gomez, María Páez de la Cadena, Francisco Javier Rodríguez-Berrocal, Joaquín Cubiella, Vicent Hernandez Ramirez, Laura García-Nimo, Loretta De Chiara
Publikováno v:
Diagnostics, Vol 10, Iss 7, p 437 (2020)
Aberrant DNA methylation detected in liquid biopsies is a promising approach for colorectal cancer (CRC) detection, including premalignant advanced adenomas (AA). We evaluated the diagnostic capability of serum NEUROG1 methylation for the detection o
Externí odkaz:
https://doaj.org/article/85476ec0571249c9908fae91bf0fede1
Autor:
Loretta De Chiara, Ana M Rodríguez-Piñeiro, Oscar J Cordero, Lidia Vázquez-Tuñas, Daniel Ayude, Francisco J Rodríguez-Berrocal, María Páez de la Cadena
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107470 (2014)
One of the main aims of the follow-up after curative resection of colorectal cancer is the early detection and treatment of tumor recurrence. We previously demonstrated decreased preoperative soluble CD26 (sCD26) levels in serum from colorectal cance
Externí odkaz:
https://doaj.org/article/4d3a42175c5249f9b4eacbc6bdb5e4b2
Autor:
María Gallardo-Gómez, Lara Costas-Ríos, Carlos A. Garcia-Prieto, Lara Álvarez-Rodríguez, Luis Bujanda, Maialen Barrero, Antoni Castells, Francesc Balaguer, Rodrigo Jover, Manel Esteller, Antoni Tardío Baiges, Joaquín González-Carreró Fojón, Joaquín Cubiella, Loretta De Chiara
ObjectiveThe clinical relevance of the serrated pathway of colorectal carcinogenesis is evident but the screening of serrated lesions remains challenging. We aimed to characterize the serum methylome of the serrated pathway, and to evaluate circulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f29b2a70831d094ad882e4196f0c9c
https://doi.org/10.1101/2022.03.25.22272961
https://doi.org/10.1101/2022.03.25.22272961
Publikováno v:
Foundations of Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d74d6a1891d9219aab882fb99649327e
https://doi.org/10.1016/b978-0-323-90055-3.00055-7
https://doi.org/10.1016/b978-0-323-90055-3.00055-7