Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Loretta Bober"'
Autor:
Hong Lan, Cliff C. Cheng, Timothy J. Kowalski, Ling Pang, Lixin Shan, Cheng-Chi Chuang, James Jackson, Alberto Rojas-Triana, Loretta Bober, Li Liu, Johannes Voigt, Peter Orth, Xianshu Yang, Jr. Gerald W. Shipps, Joseph A. Hedrick
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 4, Pp 646-656 (2011)
Fatty acid binding protein-4 (FABP4) and FABP5 are two closely related FA binding proteins expressed primarily in adipose tissue and/or macrophages. The small-molecule FABP4 inhibitor BMS309403 was previously reported to improve insulin sensitivity i
Externí odkaz:
https://doaj.org/article/4b996eda763348e98189f8126dd31a7e
Autor:
Laura W. Engstrom, Loretta Bober, Shu-Cheng Chen, Jay S. Fine, Ying Li, Michaela C. Stanton, David Kinsley, Long Cui, James V. Jackson, Alberto Rojas-Triana, Daniel Lundell, Maureen Laverty, Eric L. Gustafson, Chung-Her Jenh, Timothy J. Kowalski, Denise J. Manfra
Publikováno v:
PPAR Research, Vol 2010 (2010)
The kinetics of metabolic and inflammatory parameters associated with obesity were evaluated in a murine diet-induced obesity (DIO) model using a diet high in fat and cholesterol. Cellular infiltration and mediator production were assessed and shown
Externí odkaz:
https://doaj.org/article/cae9bc5d7d7f4e2ba1dbbdd988dcff99
Autor:
Deen Tulshian, Guoqing Li, Thierry O. Fischmann, James R. Tata, James Fossetta, Ginny D. Ho, Xiaoda Niu, Sunil Paliwal, James Jackson, W. Michael Seganish, William T. McElroy, Charles G. Garlisi, Kristine Devito, Christopher Sondey, Hong Bian, Loretta Bober, Daniel Lundell, Zheng Tan
IRAK4 is a critical upstream kinase in the IL-1R/TLR signaling pathway. Inhibition of IRAK4 is hypothesized to be beneficial in the treatment of autoimmune related disorders. A screening campaign identified a pyrazole class of IRAK4 inhibitors that w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eec17ea3324013fccf2930366388de0
https://europepmc.org/articles/PMC4468401/
https://europepmc.org/articles/PMC4468401/
Autor:
James, Fossetta, James, Jackson, Gregory, Deno, Xuedong, Fan, Karen, Du Xixuan, Loretta, Bober, Anne, Soud-Bermejo, Odette, de Bouteiller, Christophe, Caux, Charles, Lunn, Daniel, Lundell, Kyle, Palmer R
Publikováno v:
Molecular Pharmacology; February 2003, Vol. 63 Issue: 2 p342-50, 9p