An essential role for decorin in bladder cancer invasiveness

Autor: Mohamed El Behi, Sophie Krumeich, Catalina Lodillinsky, Aurélie Kamoun, Lorenzo Tibaldi, Gaël Sugano, Aurélien De Reynies, Elodie Chapeaublanc, Agnès Laplanche, Thierry Lebret, Yves Allory, François Radvanyi, Olivier Lantz, Ana María Eiján, Isabelle Bernard‐Pierrot, Clotilde Théry

Publikováno v: EMBO Molecular Medicine, Vol 5, Iss 12, Pp 1835-1851 (2013)

Abstract Muscle‐invasive forms of urothelial carcinomas are responsible for most mortality in bladder cancer. Finding new treatments for invasive bladder tumours requires adequate animal models to decipher the mechanisms of progression, in particul

Externí odkaz: https://doaj.org/article/7d331dee47ad4995aab0a027d76f3d77

New blocking antibodies impede adhesion, migration and survival of ovarian cancer cells, highlighting MFGE8 as a potential therapeutic target of human ovarian carcinoma.

Autor: Lorenzo Tibaldi, Shirley Leyman, André Nicolas, Sofie Notebaert, Melissa Dewulf, Thu Hoa Ngo, Claudia Zuany-Amorim, Nathalie Amzallag, Isabelle Bernard-Pierrot, Xavier Sastre-Garau, Clotilde Théry

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e72708 (2013)

Milk Fat Globule--EGF--factor VIII (MFGE8), also called lactadherin, is a secreted protein, which binds extracellularly to phosphatidylserine and to αvβ3 and αvβ5 integrins. On human and mouse cells expressing these integrins, such as endothelial

Externí odkaz: https://doaj.org/article/6cb2a11006d24a5a9efd1ec4b276c1ba

Abstract 1475: Microbiome derived peptides stimulate strong immune response against tumor associated antigens and trigger in vivo tumor regression after vaccination

Autor: Christophe Bonny, Laurent Chene, Celia Mendez, Lorenzo Tibaldi, Francesco Strozzi, Simon Baeriswyl, Joao Magalhaes, Caroline Diveu Sader, Arnaud Laveissière

Publikováno v: Cancer Research. 79:1475-1475

Peptide-based vaccination is an immunotherapeutic approach for the treatment of cancer that aims to deliver immunogenic peptides corresponding to specific tumor associated antigens to patients. Despite promising pre-clinical results in animal models,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e6ba2b8ca7884bb7be3bc5fbe5336fe
https://doi.org/10.1158/1538-7445.am2019-1475

Choroid-Plexus-Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity

Autor: Henry H.C. Lee, Ariel A. Di Nardo, Alain Joliot, Lorenzo Tibaldi, Julien Spatazza, Takao K. Hensch, Alain Prochiantz

Publikováno v: Cell Reports
Cell Reports, Elsevier Inc, 2013, ⟨10.1016/j.celrep.2013.05.014⟩
Cell Reports, 2013, ⟨10.1016/j.celrep.2013.05.014⟩
Cell Reports, Elsevier Inc, 2013, 3 (6), pp.1815-1823. ⟨10.1016/j.celrep.2013.05.014⟩
Cell Reports, Vol 3, Iss 6, Pp 1815-1823 (2013)

International audience; Brain plasticity is often restricted to critical periods in early life. Here, we show that a key regulator of this process in the visual cortex, Otx2 homeoprotein, is synthesized and secreted globally from the choroid plexus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e04d7e56c5361a9b0adeab721d9eec
https://doi.org/10.1016/j.celrep.2013.05.014

Optimized transfection protocol for efficient in vitro non-viral polymeric gene delivery to human retinal pigment epithelial cells (ARPE-19)

Autor: Alain Joliot, Etienne Schacht, Marjo Yliperttula, Peter Dubruel, Arto Urtti, Astrid Subrizi, Lorenzo Tibaldi

Publikováno v: Protocol Exchange.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3ddd2185a4ae8b400325f476121b217
https://doi.org/10.1038/nprot.2009.78