Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lorenzo Righetto"'
Autor:
Fabio Pammolli, Lorenzo Righetto, Sergio Abrignani, Luca Pani, Pier Giuseppe Pelicci, Emanuele Rabosio
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Studies on the early 2000s documented increasing attrition rates and duration of clinical trials, leading to a representation of a “productivity crisis” in pharmaceutical research and development (R&D). In this paper, we produ
Externí odkaz:
https://doaj.org/article/6473ecfb7f874b2e98e9ce2f974ca595
Autor:
Chiara Vanalli, Lorenzo Mari, Lorenzo Righetto, Renato Casagrandi, Marino Gatto, Isabella M Cattadori
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1008438 (2020)
Variation in the intensity and duration of infections is often driven by variation in the network and strength of host immune responses. While many of the immune mechanisms and components are known for parasitic helminths, how these relationships cha
Externí odkaz:
https://doaj.org/article/3d3e533e29c54e64a33c79bd17805c50
Autor:
Luca Pani, Emanuele Rabosio, Pier Giuseppe Pelicci, Fabio Pammolli, Sergio Abrignani, Lorenzo Righetto
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Journal of Translational Medicine
Journal of Translational Medicine
Background Studies on the early 2000s documented increasing attrition rates and duration of clinical trials, leading to a representation of a “productivity crisis” in pharmaceutical research and development (R&D). In this paper, we produce a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48e7b67350411defd82e05ec5326271
http://link.springer.com/article/10.1186/s12967-020-02313-z
http://link.springer.com/article/10.1186/s12967-020-02313-z
Publikováno v:
Journal of Informetrics. 13:583-592
Within the perimeter of patent collaboration networks, the average distance of collaborations and the number of countries involved per each collaboration have been shown to have increased steadily in time. Less attention, though, has been devoted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c1c7b1e501bff26045785a88701bcb
https://doi.org/10.1016/j.joi.2019.02.010
https://doi.org/10.1016/j.joi.2019.02.010
Autor:
Luca Pani, Fabio Pammolli, Lorenzo Righetto, Pier Giuseppe Pelicci, Sergio Abrignani, Emanuele Rabosio
Analyses of pharmaceutical pipelines of drug development in the 1990-2010 documented progressively increasing attrition rates and duration of clinical trials, leading to a diffuse perception of a “productivity crisis”. We produced a new set of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3b8cbfcb417233aad29402c2a30eea
Autor:
Isabella M. Cattadori, Lorenzo Righetto, Renato Casagrandi, Lorenzo Mari, Marino Gatto, Chiara Vanalli
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1008438 (2020)
PLoS Computational Biology
PLoS Computational Biology
Variation in the intensity and duration of infections is often driven by variation in the network and strength of host immune responses. While many of the immune mechanisms and components are known for parasitic helminths, how these relationships cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192b535a110f79ae2c9f0869da33be18
https://doi.org/10.1371/journal.pcbi.1008438
https://doi.org/10.1371/journal.pcbi.1008438
Autor:
Marino Gatto, Enrico Bertuzzo, Ignacio Rodriguez-Iturbe, Megan Murray, Silvan Manuel Vesenbeckh, Andrea Rinaldo, Renato Casagrandi, Melanie Blokesch, Lorenzo Mari, Lorenzo Righetto
Publikováno v:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences
Mathematical models can provide key insights into the course of an ongoing epidemic, potentially aiding real-time emergency management in allocating health care resources and by anticipating the impact of alternative interventions. We study the ex po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5fcfb38e42778b7375e696b21c6e6c
Autor:
Lorenzo Mari, Enrico Bertuzzo, Ignacio Rodriguez-Iturbe, Marino Gatto, Renato Casagrandi, Lorenzo Righetto, Andrea Rinaldo
Publikováno v:
JOURNAL OF THE ROYAL SOCIETY INTERFACE
Journal of The Royal Society Interface
Journal of The Royal Society Interface
We investigate the role of human mobility as a driver for long-range spreading of cholera infections, which primarily propagate through hydrologically controlled ecological corridors. Our aim is to build a spatially explicit model of a disease epidem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbda191c46ede7bf4ee04ac9dea7c9fd
Autor:
Marino Gatto, Lorenzo Righetto, Renato Casagrandi, Enrico Bertuzzo, Lorenzo Mari, Andrea Rinaldo, Ignacio Rodriguez-Iturbe
Publikováno v:
Ecohydrology. 5:531-540
We investigate the role of human mobility as a driver for long-range spreading of cholera infections, which otherwise primarily propagate through hydrologically controlled ecological corridors. We rely on a recent mechanistic, field-data validated, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94df6917e2b1a8c31c8edbb48957e5ff
https://doi.org/10.1002/eco.262
https://doi.org/10.1002/eco.262
Autor:
Andrea Rinaldo, Lorenzo Righetto, Marino Gatto, Renato Casagrandi, Ignacio Rodriguez-Iturbe, Enrico Bertuzzo, Lorenzo Mari
Publikováno v:
The American Naturalist
Waterborne pathogens cause many possibly lethal human diseases. We derive the condition for pathogen invasion and subsequent disease outbreak in a territory with specific, space-inhomogeneous characteristics (hydrological, ecological, demographic, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5d7ab620a890b3b12b78c9a54eee37
http://hdl.handle.net/11577/2806887
http://hdl.handle.net/11577/2806887