Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Lorenzo Memeo"'
Autor:
Giulia Schiavoni, Beatrice Messina, Stefano Scalera, Lorenzo Memeo, Cristina Colarossi, Marzia Mare, Giovanni Blandino, Gennaro Ciliberto, Giulia Bon, Marcello Maugeri-Saccà
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background First identified in Drosophila melanogaster, the Hippo pathway is considered a major regulatory cascade controlling tissue homeostasis and organ development. Hippo signaling components include kinases whose activity regulates YAP
Externí odkaz:
https://doaj.org/article/c14aefa5d7e340788e63b87dea7ef150
Autor:
Giuseppe Angelico, Giulio Attanasio, Lorenzo Colarossi, Cristina Colarossi, Matteo Montalbano, Eleonora Aiello, Federica Di Vendra, Marzia Mare, Nicolas Orsi, Lorenzo Memeo
Publikováno v:
Cancers, Vol 16, Iss 11, p 2062 (2024)
AT-rich interaction domain 1 (ARID1A) is a pivotal gene with a significant role in gastrointestinal tumors which encodes a protein referred to as BAF250a or SMARCF1, an integral component of the SWI/SNF (SWItch/sucrose non-fermentable) chromatin remo
Externí odkaz:
https://doaj.org/article/8493958db19a4749b35ac3039da9f8b5
Autor:
Giulia Schiavoni, Beatrice Messina, Stefano Scalera, Lorenzo Memeo, Cristina Colarossi, Marzia Mare, Giovanni Blandino, Gennaro Ciliberto, Giulia Bon, Marcello Maugeri-Saccà
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/2c0ecf02d655451b8ccd3e64d671661d
Autor:
Veronica Veschi, Alice Turdo, Chiara Modica, Francesco Verona, Simone Di Franco, Miriam Gaggianesi, Elena Tirrò, Sebastiano Di Bella, Melania Lo Iacono, Vincenzo Davide Pantina, Gaetana Porcelli, Laura Rosa Mangiapane, Paola Bianca, Aroldo Rizzo, Elisabetta Sciacca, Irene Pillitteri, Veronica Vella, Antonino Belfiore, Maria Rita Bongiorno, Giuseppe Pistone, Lorenzo Memeo, Lorenzo Colarossi, Dario Giuffrida, Cristina Colarossi, Paolo Vigneri, Matilde Todaro, Giorgio Stassi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Thyroid carcinoma (TC) is the most common malignancy of endocrine organs. Here, the authors show the ability of human embryonic stem cells (hESCs) to recapitulate the different TC histotypes upon specific genomic alterations delivered by CRISPR-Cas9
Externí odkaz:
https://doaj.org/article/ebd761e297f5412baf73304e9e1e2d72
Autor:
Beatrice Messina, Federica Lo Sardo, Stefano Scalera, Lorenzo Memeo, Cristina Colarossi, Marzia Mare, Giovanni Blandino, Gennaro Ciliberto, Marcello Maugeri-Saccà, Giulia Bon
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The Hippo pathway plays a critical role for balancing proliferation and differentiation, thus regulating tissue homeostasis. The pathway acts through a kinase cascade whose final effectors are the Yes-associated protein (YAP) and its paralog
Externí odkaz:
https://doaj.org/article/d8c786c530d4454f9a069801f79093c7
Publikováno v:
Current Oncology, Vol 29, Iss 9, Pp 6433-6444 (2022)
In recent years, advances of anticancer and supportive therapies have determined a gradual improvement in survival rates and patients’ general conditions in metastatic gastric cancer (mGC), allowing them to receive further treatments. The choice of
Externí odkaz:
https://doaj.org/article/ad9cdd23b88240ce9eb246d70c300412
Autor:
Giuseppe Angelico, Giuseppe Broggi, Giordana Tinnirello, Lidia Puzzo, Giada Maria Vecchio, Lucia Salvatorelli, Lorenzo Memeo, Angela Santoro, Jessica Farina, Antonino Mulé, Gaetano Magro, Rosario Caltabiano
Publikováno v:
Cancers, Vol 15, Iss 18, p 4479 (2023)
With the rise of novel immunotherapies able to stimulate the antitumor immune response, increasing literature concerning the immunogenicity of breast cancer has been published in recent years. Numerous clinical studies have been conducted in order to
Externí odkaz:
https://doaj.org/article/802e67ca9b714911b775798a36d37326
Autor:
Simone Di Franco, Paola Bianca, Davide Stefano Sardina, Alice Turdo, Miriam Gaggianesi, Veronica Veschi, Annalisa Nicotra, Laura Rosa Mangiapane, Melania Lo Iacono, Irene Pillitteri, Sander van Hooff, Federica Martorana, Gianmarco Motta, Eliana Gulotta, Vincenzo Luca Lentini, Emanuele Martorana, Micol Eleonora Fiori, Salvatore Vieni, Maria Rita Bongiorno, Giorgio Giannone, Dario Giuffrida, Lorenzo Memeo, Lorenzo Colarossi, Marzia Mare, Paolo Vigneri, Matilde Todaro, Ruggero De Maria, Jan Paul Medema, Giorgio Stassi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Obesity is a major risk factor for cancer related death. Here, the authors show that visceral adipose-derived factors promote vasculogenesis and metastatic dissemination by activation of STAT3, which inhibits miR-200a and enhances ZEB2 expression, ef
Externí odkaz:
https://doaj.org/article/4290ce7ba4614241baeb5615eb552e3e
Autor:
Rosario Leonardi, Alessandro Calarco, Lorenzo Falcone, Vincenzo Grasso, Marco Frisenda, Antonio Tufano, Pietro Viscuso, Antonio Rossi, Lorenzo Memeo
Publikováno v:
Archivio Italiano di Urologia e Andrologia, Vol 94, Iss 2 (2022)
Introduction: Bladder cancer is one of the most common tumors among the general population. The first surgical approach to the tumor is often the transurethral resection with monopolar or bipolar loop. Recently, laser energy has become an alternative
Externí odkaz:
https://doaj.org/article/195a3053e38348e6a570812e081b5fe9
Autor:
Cristina Colarossi, Maria Carolina Picardo, Lorenzo Colarossi, Enrica Deiana, Costanza D'Agata, Corrado Fichera, Eleonora Aiello, Giorgio Giannone, Lorenzo Memeo
Publikováno v:
Frontiers in Surgery, Vol 8 (2021)
Clear cell carcinoma is a clinically and biologically distinct type of carcinoma predominantly encountered in the ovary and endometrium. In the ovary, it is frequently associated with endometriosis, which is a well-known risk factor. Endometriosis ha
Externí odkaz:
https://doaj.org/article/6f1a2f79c311414ebcfa93955cfee21c