Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Lorenzo Franci"'
Autor:
Lorenzo Franci, Giulia Vallini, Franca Maria Bertolino, Vittoria Cicaloni, Giovanni Inzalaco, Mattia Cicogni, Laura Tinti, Laura Calabrese, Virginia Barone, Laura Salvini, Pietro Rubegni, Federico Galvagni, Mario Chiariello
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103131- (2024)
Oxidation processes in mitochondria and different environmental insults contribute to unwarranted accumulation of reactive oxygen species (ROS). These, in turn, rapidly damage intracellular lipids, proteins, and DNA, ultimately causing aging and seve
Externí odkaz:
https://doaj.org/article/0dc7ea96e7b34192be7de7d6ee8e239c
Autor:
Lisa Gherardini, Veronica Vetri Buratti, Mirko Maturi, Giovanni Inzalaco, Erica Locatelli, Letizia Sambri, Sara Gargiulo, Virginia Barone, Denise Bonente, Eugenio Bertelli, Silvia Tortorella, Lorenzo Franci, Antonio Fioravanti, Mauro Comes Franchini, Mario Chiariello
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Glioblastoma multiforme (GBM) is the most aggressive primary tumor of the central nervous system and the diagnosis is often dismal. GBM pharmacological treatment is strongly limited by its intracranial location beyond the blood–brain barri
Externí odkaz:
https://doaj.org/article/a673b4ee4c384c1aae31d45e333b78fc
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 381-384 (2022)
Aberrant production of reactive oxygen species (ROS) from dysfunctional mitochondria leads to oxidative stress and DNA damage, which induces the cellular senescence stress response pathway. This, while exerting strong beneficial suppressive effects o
Externí odkaz:
https://doaj.org/article/a0b54d8f5cba41188b29de16b455bc8b
Autor:
Leire Iralde-Lorente, Ylenia Cau, Letizia Clementi, Lorenzo Franci, Giusy Tassone, Daniela Valensin, Mattia Mori, Adriano Angelucci, Mario Chiariello, Maurizio Botta
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 657-664 (2019)
14-3-3 are regulatory proteins that through protein–protein interactions (PPI) with numerous binding partners could be involved in several human diseases, including cancer, neurodegenerative disorders, and pathogens infections. Following our resear
Externí odkaz:
https://doaj.org/article/0387ca67151143d8bee11b1f00a12246
Autor:
Barone, Denise Bonente, Laura Bianchi, Rossana De Salvo, Claudio Nicoletti, Elena De Benedetto, Tommaso Bacci, Luca Bini, Giovanni Inzalaco, Lorenzo Franci, Mario Chiariello, Gian Marco Tosi, Eugenio Bertelli, Virginia
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9728
Epiretinal membranes (ERMs) are sheets of tissue that pathologically develop in the vitreoretinal interface leading to progressive vision loss. They are formed by different cell types and by an exuberant deposition of extracellular matrix proteins. R
Publikováno v:
Autophagy Reports. 1:381-384
Autor:
Leire Iralde-Lorente, Giusy Tassone, Ylenia Cau, Claire Munier, Lorenzo Franci, Cecilia Pozzi, Adriano Angelucci, Mario Chiariello, Matthew Perry, Stefano Mangani, Maurizio Botta
Publikováno v:
Proceedings, Vol 22, Iss 1, p 17 (2019)
c-Abl is a tyrosine kinase implicated in the regulation of proliferation, adhesion, motility, andcell survival [...]
Externí odkaz:
https://doaj.org/article/bae4c4cff99d45deba1ba399c8422f85
Autor:
Lorenzo Franci, Alessandro Tubita, Franca Maria Bertolino, Elisabetta Rovida, Mario Chiariello
Publikováno v:
Free Radical Biology and Medicine. 198:S18
Autor:
Lorenzo Franci, Alessandro Tubita, Franca Maria Bertolino, Alessandro Palma, Giuseppe Cannino, Carmine Settembre, Andrea Rasola, Elisabetta Rovida, Mario Chiariello
Mitochondria are the major source of reactive oxygen species (ROS), whose aberrant production by dysfunctional mitochondria leads to oxidative stress, thus contributing to aging as well as neurodegenerative disorders and cancer. Cells efficiently eli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5fe52184d76abbb99dee17a63b0432
https://hdl.handle.net/11573/1678333
https://hdl.handle.net/11573/1678333
Autor:
Cristina Zanini, Mario Chiariello, Francesco Imperatore, Silvia Pietrobono, Barbara Stecca, Lorenzo Franci
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4903, p 4903 (2021)
Volume 13
Issue 19
Cancers, Vol 13, Iss 4903, p 4903 (2021)
Volume 13
Issue 19
Simple Summary In eukaryotes, MAPK15 controls the assembly of primary cilia, which are microtubule-based cell surface organelles necessary for sensing and processing developmental signals as well as for transducing tumorigenic Hedgehog signaling in m