Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Lorenzo Flori"'
Publikováno v:
Pharmacological Research, Vol 207, Iss , Pp 107334- (2024)
The intestinal microbiota represents a key element in maintaining the homeostasis and health conditions of the host. Vascular pathologies and other risk factors such as aging have been recently associated with dysbiosis. The qualitative and quantitat
Externí odkaz:
https://doaj.org/article/4e047b7eb2c7447bbf07a7b93c14c419
Autor:
Eugenia Piragine, Martina De Felice, Lorenzo Germelli, Vanessa Brinkmann, Lorenzo Flori, Claudia Martini, Vincenzo Calderone, Natascia Ventura, Eleonora Da Pozzo, Lara Testai
Publikováno v:
Experimental Gerontology, Vol 194, Iss , Pp 112495- (2024)
Aging is one of the main risk factors for neurodegenerative disorders, which represent a global burden on healthcare systems. Therefore, identifying new strategies to slow the progression of brain aging is a compelling challenge. In this article, we
Externí odkaz:
https://doaj.org/article/2aafe5b68c084df8b5bb4c954508caf7
Autor:
Lorenzo Flori, Giulia Lazzarini, Jacopo Spezzini, Andrea Pirone, Vincenzo Calderone, Lara Testai, Vincenzo Miragliotta
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116534- (2024)
The isoproterenol (ISO)-induced myocardial fibrosis is considered a reliable and repeatable experimental model characterized by a relatively low mortality rate. Although is well-known that ISO stimulates the β1 adrenergic receptors at the myocardial
Externí odkaz:
https://doaj.org/article/2526eba311714480b4ce5dfd4c686f8b
Autor:
Valentina Citi, Serenella Torre, Lorenzo Flori, Luca Usai, Nazlim Aktay, Nurhan Turgut Dunford, Giovanni Antonio Lutzu, Paola Nieri
Publikováno v:
Nutrients, Vol 16, Iss 11, p 1752 (2024)
Arthrospira platensis, commonly known as Spirulina, is a photosynthetic filamentous cyanobacterium (blue–green microalga) that has been utilized as a food source since ancient times. More recently, it has gained significant popularity as a dietary
Externí odkaz:
https://doaj.org/article/a77728771be14ac4a548fb69d781c89e
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 543 (2024)
Irisin is a myokine secreted under the influence of physical activity and exposure to low temperatures and through different exogenous stimuli by the cleavage of its precursor, fibronectin type III domain-containing protein 5 (FNDC5). It is mainly kn
Externí odkaz:
https://doaj.org/article/5964e6ba918f44a9bb760d544b28f1b2
Autor:
Giada Benedetti, Lorenzo Flori, Jacopo Spezzini, Vincenzo Miragliotta, Giulia Lazzarini, Andrea Pirone, Cosimo Meneguzzo, Luca Tagliavento, Alma Martelli, Michele Antonelli, Davide Donelli, Cecilia Faraloni, Vincenzo Calderone, Francesco Meneguzzo, Lara Testai
Publikováno v:
Nutrients, Vol 16, Iss 4, p 506 (2024)
The healthy properties of pomegranate fruit, a highly consumed food, have been known for a long time. However, the pomegranate supply chain is still rather inefficient, with the non-edible fraction, whose weight is roughly half the total and is endow
Externí odkaz:
https://doaj.org/article/709cbe948d2f494282dfb408f16ac519
Autor:
Lorenzo Flori, Rosangela Montanaro, Eleonora Pagnotta, Luisa Ugolini, Laura Righetti, Alma Martelli, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Vincenzo Brancaleone, Lara Testai, Vincenzo Calderone
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3281 (2023)
Modulation of mitochondrial K channels represents a pharmacological strategy to promote cardioprotective effects. Isothiocyanates emerge as molecules capable of releasing hydrogen sulfide (H2S), an endogenous pleiotropic gasotransmitter responsible f
Externí odkaz:
https://doaj.org/article/8e567d5631784c1c9c6073e4309f3f89
Publikováno v:
Computation, Vol 11, Iss 12, p 255 (2023)
In this study, we applied a computer-based protocol to identify novel antioxidant agents that can reduce oxidative stress (OxS), which is one of the main hallmarks of several disorders, including cancer, cardiovascular disease, and neurodegenerative
Externí odkaz:
https://doaj.org/article/b65d02c201b342f297277379ebdf70b5
Autor:
Lorenzo Flori, Eugenia Piragine, Jacopo Spezzini, Valentina Citi, Vincenzo Calderone, Alma Martelli
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9276 (2023)
Adipose tissue (AT) can be classified into two different types: (i) white adipose tissue (WAT), which represents the largest amount of total AT, and has the main function of storing fatty acids for energy needs and (ii) brown adipose tissue (BAT), ri
Externí odkaz:
https://doaj.org/article/1ccdf80e4d624ac2ae62841b947cebfa
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7578 (2023)
In this paper, we present the development of a computer-based repurposing approach to identify FDA-approved drugs that are potentially able to interfere with irisin dimerization. It has been established that altered levels of irisin dimers are a pure
Externí odkaz:
https://doaj.org/article/24c789c4a7ba439b844b3331665cc053