Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lorenzo Caruana"'
Publikováno v:
Molecules, Vol 20, Iss 7, Pp 11733-11764 (2015)
Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive” intermediates, or even as a “synthetic enigma” in organic chemistry. Indeed, there were just a handful of examples of their utilization in catalytic asym
Externí odkaz:
https://doaj.org/article/52cc9c5f215f452c8d1b52a765089b91
Autor:
Julie Febvay, Andrea Mazzanti, Patricia Camarero Gonzalez, Luca Bernardi, Mariafrancesca Fochi, Vasco Corti, Lorenzo Caruana
Publikováno v:
European Journal of Organic Chemistry. 2017:49-52
1,5-Benzothiazepine frameworks are highly relevant in medicinal chemistry. Reported catalytic asymmetric approaches to these scaffolds have targeted 2,3-dihydro-1,5-benzothiazepin-4-ones, leaving the corresponding amines (2,3,4,5-tetrahydro-1,5-benzo
Autor:
Vasco Corti, Martina Mondatori, Lorenzo Caruana, Mariafrancesca Fochi, Luca Bernardi, Andrea Mazzanti, Sara Morales
Publikováno v:
Chemistry - A European Journal. 21:6037-6041
A new approach to the utilization of highly reactive and unstable ortho-quinone methides (o-QMs) in catalytic asymmetric settings is presented. The enantioselective reactions are catalysed by bifunctional organocatalysts, and the o-QM intermediates a
Autor:
Lorenzo Caruana, Andrea Mazzanti, Giulio Bertuzzi, Alessandro Sinisi, Mariafrancesca Fochi, Luca Bernardi
Publikováno v:
ACS Catalysis. 6:6473-6477
The catalytic enantioselective dearomatization of pyridines with nucleophiles represents a direct and convenient access to highly valuable dihydropyridines. Available methods, mostly based on N-acylpyridinium salts, give addition to the C-2/C-6 of th
Publikováno v:
Synthesis. 46:135-157
The Povarov reaction provides a straightforward and modular entry to 1,2,3,4-tetrahydroquinolines (THQs). Despite its importance, it was only very recently that several highly efficient catalytic asymmetric protocols for this reaction have been devel
Publikováno v:
Molecules, Vol 20, Iss 7, Pp 11733-11764 (2015)
Molecules
Molecules
Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive” intermediates, or even as a “synthetic enigma” in organic chemistry. Indeed, there were just a handful of examples of their utilization in catalytic asym
Autor:
Daniel Pecorari, Andrea Mazzanti, Luca Bernardi, Mariafrancesca Fochi, Giulio Bertuzzi, Lorenzo Caruana, Alessandro Sinisi
Publikováno v:
Organic letters. 19(4)
Catalytic addition of chiral enamines to azinium salts is a powerful tool for the synthesis of enantioenriched heterocycles. An unprecedented asymmetric dearomative addition of aldehydes to activated N-alkylpyridinium salts is presented. The process
Organocatalytic domino reactions of 4-substituted indoles are summarized in this account. Two reactions have been developed, one with enals, activated by secondary amine catalysts via iminium ions, and one with nitroethene, using a phosphoric acid ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fee1d9b05d29ecba936645653471470
http://hdl.handle.net/11585/621564
http://hdl.handle.net/11585/621564
Autor:
Lorenzo Caruana, Karl Anker Jørgensen, Pernille H. Poulsen, Florian Kniep, Tore Kiilerich Johansen
Publikováno v:
Caruana, L, Kniep, F, Johansen, T K, Poulsen, P H & Jorgensen, K A 2014, ' A New Organocatalytic Concept for Asymmetric alpha-Alkylation of Aldehydes ', Journal of the American Chemical Society, vol. 136, no. 45, pp. 15929-15932 . https://doi.org/10.1021/ja510475n
The organocatalytic asymmetric alpha-alkylation of aldehydes by 1,6-conjugated addition of enamines to p-quinone methides is described. Employing a newly developed class of chiral secondary amine catalysts, alpha-diarylmethine-substituted aldehydes w
Autor:
Pedro Blas González, Mauro Comes Franchini, Lorenzo Caruana, Mariafrancesca Fochi, Jay Zumbar Chandanshive, Luca Bernardi, Andrea Mazzanti, Erica Locatelli, Claudio Monasterolo, Bianca F. Bonini
Publikováno v:
European Journal of Organic Chemistry. 2013:8108-8114
The reactivity of the ynamide tert-butyl N-ethynyl-N-phenylcarbamate (1) in the 1,3-dipolar cycloaddition (1,3-DC) with C-carboxymethyl-N-phenylnitrilimine was investigated. This [3+2] cycloaddition affords the 5-amino pyrazole as a single regioisome