Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lorenzo Barolo"'
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Chlamydomonas reinhardtii is gaining recognition as a promising expression system for the production of recombinant proteins. However, its performance as a cellular biofactory remains suboptimal, especially with respect to consist
Externí odkaz:
https://doaj.org/article/e4b7b6ae820a41e88a3ab668dc83a955
Autor:
Lorenzo Barolo, Ylenia Gigante, Lorenza Mautone, Silvia Ghirga, Alessandro Soloperto, Alessandra Giorgi, Francesca Ghirga, Martina Pitea, Alessio Incocciati, Francesco Mura, Giancarlo Ruocco, Alberto Boffi, Paola Baiocco, Silvia Di Angelantonio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Tauopathies, including Alzheimer’s disease and Frontotemporal Dementia, are debilitating neurodegenerative disorders marked by cognitive decline. Despite extensive research, achieving effective treatments and significant symptom management
Externí odkaz:
https://doaj.org/article/d69b351b7e094759bfd10aa20ce9dd0f
Autor:
Francesca Romana Liberati, Sara Di Russo, Lorenzo Barolo, Giovanna Peruzzi, Maria Vittoria Farina, Sharon Spizzichino, Federica Di Fonzo, Deborah Quaglio, Luca Pisano, Bruno Botta, Alessandra Giorgi, Alberto Boffi, Francesca Cutruzzolà, Alessio Paone, Paola Baiocco
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 402 (2024)
Chronic lymphocytic leukemia (CLL) is a widespread type of leukemia that predominantly targets B lymphocytes, undermining the balance between cell proliferation and apoptosis. In healthy B cells, miR-15/16, a tandem of microRNAs, functions as a tumor
Externí odkaz:
https://doaj.org/article/c3cb26ae36b04029a7e08117175fdbb3
Autor:
Lorenzo Barolo, Raffaela M. Abbriano, Audrey S. Commault, Jestin George, Tim Kahlke, Michele Fabris, Matthew P. Padula, Angelo Lopez, Peter J. Ralph, Mathieu Pernice
Publikováno v:
Cells, Vol 9, Iss 3, p 633 (2020)
Microalgae exhibit great potential for recombinant therapeutic protein production, due to lower production costs, immunity to human pathogens, and advanced genetic toolkits. However, a fundamental aspect to consider for recombinant biopharmaceutical
Externí odkaz:
https://doaj.org/article/4ff625cd47d1447aad7f42097966eeaa
Autor:
Lorenzo Barolo, Audrey S. Commault, Raffaela M. Abbriano, Matthew P. Padula, Mikael Kim, Unnikrishnan Kuzhiumparambil, Peter J. Ralph, Mathieu Pernice
Abstract The green microalga Chlamydomonas reinhardtii is emerging as a promising cell biofactory for secreted recombinant protein (RP) production. In recent years, the generation of the broadly used cell wall–deficient mutant strain UVM4 has allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21c351ad8d29d957ec6607a17695965
https://hdl.handle.net/10453/164030
https://hdl.handle.net/10453/164030
Autor:
Angela Capocefalo, Silvia Gentilini, Lorenzo Barolo, Paola Baiocco, Claudio Conti, Neda Ghofraniha
Publikováno v:
Photonics Research. 11:732
Highly accurate biosensors for few or single molecule detection play a central role in numerous key fields, such as healthcare and environmental monitoring. In the last decade, laser biosensors have been investigated as proofs of concept, and several
Autor:
Raffaela M. Abbriano, Lorenzo Barolo, Mathieu Pernice, Audrey S. Commault, Tim Kahlke, Angelo Lopez, Michele Fabris, Matthew P. Padula, Jestin George, Peter J. Ralph
Publikováno v:
Cells, Vol 9, Iss 3, p 633 (2020)
Cells
Cells
Microalgae exhibit great potential for recombinant therapeutic protein production, due to lower production costs, immunity to human pathogens, and advanced genetic toolkits. However, a fundamental aspect to consider for recombinant biopharmaceutical
Autor:
Matthias Windhagauer, Mathieu Pernice, Ana Cristina Jaramillo-Madrid, Justin Ashworth, Martina A. Doblin, Raffaela M. Abbriano, Lorenzo Barolo
Publikováno v:
Algal Research. 53:102159
Phaeodactylum tricornutum is a model pennate diatom for molecular studies due to its sequenced genome, genetic tractability, and capacity to produce a myriad of compounds of biotechnological interest. While tools for genetic engineering and heterolog
Autor:
Barbara Colombini, Lorenzo Barolo, Tania Fiaschi, Marta Nocella, Tania Gamberi, Andrea Carpentieri, Massimo Gulisano, Angela Amoresano, Alessandra Modesti, Maria Angela Bagni, Francesca Magherini
Publikováno v:
Journal of Proteome Research. 15:3666-3678
Understanding the relationship between physical exercise, reactive oxygen species, and skeletal muscle modification is important in order to better identify the benefits or the damages that appropriate or inappropriate exercise can induce. Heart and
Autor:
Mathieu Pernice, Navpreet Kaur Walia, Nachshon Siboni, Peter J. Ralph, Lorenzo Barolo, Jack Adriaans, Audrey S. Commault, Michele Fabris
Publikováno v:
Algal Research. 50:101997
Microalgae are increasingly being considered for recombinant protein production because of low cultivation costs, absence of endotoxins and insusceptibility to human infectious agents. Despite these advantages, the yield of recombinant protein produc