Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lorenzo, Turelli"'
Autor:
Tony Rady, Lorenzo Turelli, Marc Nothisen, Elisabetta Tobaldi, Stéphane Erb, Fabien Thoreau, Oscar Hernandez-Alba, Sarah Cianferani, François Daubeuf, Alain Wagner, Guilhem Chaubet
Publikováno v:
Bioconjugate Chemistry. 33:1860-1866
Cleavable linkers have become the subject of intense study in the field of chemical biology, particularly because of their applications in the construction of antibody-drug conjugates (ADC), where they facilitate lysosomal cleavage and liberation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29227329a543ded2df288b4c9d817ee7
https://doi.org/10.1021/acs.bioconjchem.2c00314
https://doi.org/10.1021/acs.bioconjchem.2c00314
Publikováno v:
Organic & Biomolecular Chemistry
Here, we disclose an efficient and modular approach toward new 1,2-disubstituted bicyclo[2.1.1]hexane modules via [2 + 2] cycloaddition. The system can readily be derivatized with numerous transformations, opening the gate to sp3-rich new chemical sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a407cb2b3edbf374044f65567593f20
https://doi.org/10.1039/d2ob01669a
https://doi.org/10.1039/d2ob01669a
Publikováno v:
Organicbiomolecular chemistry. 20(46)
Among the valuable saturated bicyclic structures incorporated in newly developed bio-active compounds, bicyclo[2.1.1]hexanes are playing an increasingly important role, while being still underexplored from a synthetic accessibility point of view. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a46c366943e57c3519358abb8f992ac4
https://pubmed.ncbi.nlm.nih.gov/36350230
https://pubmed.ncbi.nlm.nih.gov/36350230
Among the valuable saturated bicyclic structures incorporated in newly developed bio-active compounds, bicyclo[2.1.1]hexanes are playing an increasingly important role, while being still underexplored from a synthetic accessibility point of view. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a4508e00e9f00b28d316fff71b30f0e
https://doi.org/10.26434/chemrxiv-2022-4hc8x
https://doi.org/10.26434/chemrxiv-2022-4hc8x
