Zobrazeno 1 - 10
of 783
pro vyhledávání: '"Lorenzo, Moretta"'
Autor:
Claudia Cantoni, Michela Falco, Massimo Vitale, Gabriella Pietra, Enrico Munari, Daniela Pende, Maria Cristina Mingari, Simona Sivori, Lorenzo Moretta
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
The long story of NK cells started about 50 y ago with the first demonstration of a natural cytotoxic activity within an undefined subset of circulating leukocytes, has involved an ever-growing number of researchers, fascinated by the apparently easy
Externí odkaz:
https://doaj.org/article/bd0d6b7413d1468ca95bb84de00f4265
Autor:
Nadine Landolina, Francesca Romana Mariotti, Andrea Pelosi, Valentina D’Oria, Tiziano Ingegnere, Claudia Alicata, Paola Vacca, Lorenzo Moretta, Enrico Maggi
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTIL-37 is a member of the IL-1 superfamily exerting anti-inflammatory functions in a number of diseases. Extracellular IL-37 triggers the inhibitory receptor IL-1R8 that is known to regulate different NK cell pathways and functional activities
Externí odkaz:
https://doaj.org/article/b9f5f48dced741a69192693a4553219a
Autor:
Nadine Landolina, Biancamaria Ricci, Irene Veneziani, Claudia Alicata, Francesca Romana Mariotti, Andrea Pelosi, Linda Quatrini, Eva Piano Mortari, Rita Carsetti, Paola Vacca, Nicola Tumino, Bruno Azzarone, Lorenzo Moretta, Enrico Maggi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIn early infected or severe coronavirus disease 2019 (COVID-19) patients, circulating NK cells are consistently reduced, despite being highly activated or exhausted. The aim of this paper was to establish whether severe acute respiratory sy
Externí odkaz:
https://doaj.org/article/187dcf51ee0548c89594a1ab4edb95fe
Autor:
Sabina Di Matteo, Maria Teresa Bilotta, Andrea Pelosi, Dorothee Haas, Tobias Theinert, Gerrit Weber, Paul-Gerhardt Schlegel, Matthias Berg, Lorenzo Moretta, Enrico Maggi, Bruno Azzarone, Paola Vacca, Nicola Tumino, Ignazio Caruana
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundNeuroblastoma (NB) is characterized by both adrenergic (ADRN) and undifferentiated mesenchymal (MES) subsets. The ganglioside sialic acid-containing glycosphingolipid (GD2) is widely overexpressed on tumors of neuroectodermal origin promoti
Externí odkaz:
https://doaj.org/article/688dd7aa1e77408e8476bbcde976133e
Autor:
Carola Perrone, Federica Bozzano, Maria Giovanna Dal Bello, Genny Del Zotto, Francesca Antonini, Enrico Munari, Enrico Maggi, Francesca Moretta, Alireza Hajabbas Farshchi, Gianluca Pariscenti, Marco Tagliamento, Carlo Genova, Lorenzo Moretta, Andrea De Maria
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThere is little information on the trajectory and developmental fate of Lin-CD34+DNAM-1bright CXCR4+ progenitors exiting bone marrow during systemic inflammation.ObjectiveTo study Lin-CD34+DNAM-1bright CXCR4+ cell circulation in cancer pati
Externí odkaz:
https://doaj.org/article/316e2aa84ab440c69c590ae740ca2724
Autor:
Anna Laura Di Pace, Andrea Pelosi, Piera Filomena Fiore, Nicola Tumino, Francesca Besi, Linda Quatrini, Silvia Santopolo, Paola Vacca, Lorenzo Moretta
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTNatural Killer (NK) cells are important components of the immune system in the defense against tumor growth and metastasis. They release exosomes containing proteins and nucleic acids, including microRNAs (miRNAs). NK-derived exosomes play a
Externí odkaz:
https://doaj.org/article/1f6252c6ed4c4ab6a860a413aa32f541
Autor:
Francesca Romana Mariotti, Tiziano Ingegnere, Nadine Landolina, Paola Vacca, Enrico Munari, Lorenzo Moretta
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
NK cells represent important effectors that play a major role in innate defences against pathogens and display potent cytolytic activity against tumor cells. An array of surface receptors finely regulate their function and inhibitory checkpoints, suc
Externí odkaz:
https://doaj.org/article/302c3fa35e62415280472322dc40a721
Autor:
Matteo Caforio, Nicola Tumino, Cristina Sorino, Isabella Manni, Stefano Di Giovenale, Giulia Piaggio, Simona Iezzi, Georgios Strimpakos, Elisabetta Mattei, Lorenzo Moretta, M. Fanciulli, Paola Vacca, Franco Locatelli, Valentina Folgiero
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAATF/Che-1 over-expression in different tumors is well known and its effect on tumorigenicity is mainly due to its central role demonstrated in the oncogenic pathways of solid tumors, where it controls proliferation and viability. The eff
Externí odkaz:
https://doaj.org/article/f5115f9bf1b74bdf9a69050d6bb081ea
Autor:
Sabina Di Matteo, Enrico Munari, Piera Filomena Fiore, Silvia Santopolo, Camilla Sampaoli, Andrea Pelosi, Salem Chouaib, Nicola Tumino, Paola Vacca, Francesca Romana Mariotti, Stefan Ebert, Markus Machwirth, Dorothee Haas, Marco Pezzullo, Gabriella Pietra, Melania Grottoli, Stephanie Buart, Erwan Mortier, Enrico Maggi, Lorenzo Moretta, Ignazio Caruana, Bruno Azzarone
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMelanoma is a lethal skin cancer, and the risk of developing it is increased by exposure to ultraviolet (UV) radiation. The production of cytokines such as interleukin-15 (IL-15), induced by the exposure of skin cells to UV rays, could also
Externí odkaz:
https://doaj.org/article/019fa5592eae43aba1002be803c63084
Autor:
Nicola Tumino, Gerrit Weber, Francesca Besi, Francesca Del Bufalo, Valentina Bertaina, Paola Paci, Linda Quatrini, Laura Antonucci, Matilde Sinibaldi, Concetta Quintarelli, Enrico Maggi, Biagio De Angelis, Franco Locatelli, Lorenzo Moretta, Paola Vacca, Ignazio Caruana
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract The outcome of patients affected by high-risk or metastatic neuroblastoma (NB) remains grim, with ≥ 50% of the children experiencing relapse or progression of the disease despite multimodal, intensive treatment. In order to identify new st
Externí odkaz:
https://doaj.org/article/51f0504736a347c6a8f2d674f1b4901c