Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Lorenzo, Gallon"'
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
Externí odkaz:
https://doaj.org/article/fad64613bc7040a4a66547ec12c8d5c4
Autor:
Zeguo Sun, Zhongyang Zhang, Khadija Banu, Ian W. Gibson, Robert B. Colvin, Zhengzi Yi, Weijia Zhang, Bony De Kumar, Anand Reghuvaran, John Pell, Thomas D. Manes, Arjang Djamali, Lorenzo Gallon, Philip J. O’Connell, John Cijiang He, Jordan S. Pober, Peter S. Heeger, Madhav C. Menon
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Donor-recipient (D-R) mismatches outside of human leukocyte antigens (HLAs) contribute to kidney allograft loss, but the mechanisms remain unclear, specifically for intronic mismatches. We quantified non-HLA mismatches at variant-, gene-, and genome-
Externí odkaz:
https://doaj.org/article/1062a57a1df84d2eb0cec1a6f8b62c10
Autor:
Ibrahim Tawhari, Patrick Hallak, Sofia Bin, Fatmah Yamani, Maria Safar-Boueri, Aazib Irshad, Joseph Leventhal, Mohammed Javeed Ansari, Paolo Cravedi, Lorenzo Gallon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundBelatacept (Bela) was developed to reduce nephrotoxicity and cardiovascular risk that are associated with the chronic use of Calcineurin inhibitors (CNIs) in kidney transplant recipients. The use of Bela with early steroid withdrawal (ESW)
Externí odkaz:
https://doaj.org/article/b395cd1a38fe475aa95ebcdd32f8779a
Autor:
Xingqiang Lai, Xin Zheng, James M. Mathew, Lorenzo Gallon, Joseph R. Leventhal, Zheng Jenny Zhang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite advances in post-transplant management, the long-term survival rate of kidney grafts and patients has not improved as approximately forty percent of transplants fails within ten years after transplantation. Both immunologic and non-immunologi
Externí odkaz:
https://doaj.org/article/d4c9dcf2ebea4452bb610d0fa47c2044
Autor:
Susan Hartzell, Sofia Bin, Chiara Cantarelli, Meredith Haverly, Joaquin Manrique, Andrea Angeletti, Gaetano La Manna, Barbara Murphy, Weijia Zhang, Josh Levitsky, Lorenzo Gallon, Samuel Mon-Wei Yu, Paolo Cravedi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Individuals with kidney failure are at increased risk of cardiovascular events, as well as infections and malignancies, but the associated immunological abnormalities are unclear. We hypothesized that the uremic milieu triggers a chronic inflammatory
Externí odkaz:
https://doaj.org/article/b701963dbcaf4c40ac3d7cc1f8e92fe5
Autor:
James M. Mathew, Jessica H.-Voss, Ann LeFever, Iwona Konieczna, Cheryl Stratton, Jie He, Xuemei Huang, Lorenzo Gallon, Anton Skaro, Mohammed Javeed Ansari, Joseph R. Leventhal
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract There is considerable interest in therapeutic transfer of regulatory T cells (Tregs) for controlling aberrant immune responses. Initial clinical trials have shown the safety of Tregs in hematopoietic stem cell transplant recipients and subje
Externí odkaz:
https://doaj.org/article/2b03555479114b16b575707b43828b2b
Autor:
Opas Traitanon, James M Mathew, Aneesha Shetty, Sai Vineela Bontha, Daniel G Maluf, Yvonne El Kassis, Sook H Park, Jing Han, M Javeed Ansari, Joseph R Leventhal, Valeria Mas, Lorenzo Gallon
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216300 (2019)
Calcineurin inhibitors (CNI), the cornerstone of immunosuppression after transplantation are implicated in nephrotoxicity and allograft dysfunction. We hypothesized that combined low doses of CNI and Everolimus (EVR) may result in better graft outcom
Externí odkaz:
https://doaj.org/article/80ca1ff8cf624560a0785c048e2da226
Autor:
Zeguo Sun, Zhongyang Zhang, Khadija Banu, Ian Gibson, Robert Colvin, Zhengzi Yi, Weijia Zhang, Bony De Kumar, John Pell, Arjang Djamali, Lorenzo Gallon, Philip O’Connell, Cijiang He, Jordan Pober, Peter Heeger, Madhav C Menon
BackgroundLong-term kidney allograft survival remains suboptimal. Emerging evidence indicates donor-recipient (D-R) mismatches outside of human leukocyte antigens (HLA) contribute to graft survival but mechanisms remain unclear, specifically for thos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::097fe3f0d1405e718a8ac09f27e1a202
https://doi.org/10.1101/2022.12.21.521481
https://doi.org/10.1101/2022.12.21.521481
Autor:
Greg Hachaj, Ivo Tzvetanov, Edward Wang, Mario Spaggiari, Bo Fernhall, Bruce Kaplan, Aneesha Shetty, Alexandra Kastelz, Lorenzo Gallon, Enrico Benedetti
Publikováno v:
Transplant International. 34:1083-1092
Kidney transplantation is the preferred treatment for kidney failure; however after transplant, reduced physical function, poor self-perceptions, and unemployment are common concerns that remain. This randomized controlled trial compared the effects
Autor:
Kellie J. Archer, Elissa Bardhi, Daniel G. Maluf, Jennifer McDaniels, Thomas Rousselle, Anne King, James D. Eason, Lorenzo Gallon, Enver Akalin, Thomas F. Mueller, Valeria R. Mas
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 22(11)
With the development of novel prognostic tools derived from omics technologies, transplant medicine is entering the era of precision medicine. Currently, there are no established predictive biomarkers for posttransplant kidney function. A total of 27