Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Lorenzo, Caputi"'
Publikováno v:
Materials, Vol 17, Iss 9, p 1941 (2024)
Graphene is undoubtedly the carbon allotrope that has attracted the attention of a myriad of researchers in the last decades more than any other. The interaction of external or intercalated Li and Li+ with graphene layers has been the subject of part
Externí odkaz:
https://doaj.org/article/620ca8c76dab40539adad340f747a2be
Autor:
Quentin M. Dudley, Seohyun Jo, Delia Ayled Serna Guerrero, Monika Chhetry, Mark A. Smedley, Wendy A. Harwood, Nathaniel H. Sherden, Sarah E. O’Connor, Lorenzo Caputi, Nicola J. Patron
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
The biosynthesis of strictosidine, a key intermediate of monoterpene indole alkaloids, was successfully reconstructed in Nicotiana benthamiana, demonstrating the potential of Nicotiana benthamiana as a bioproduction chassis for small molecules.
Externí odkaz:
https://doaj.org/article/e29c0ea27a5d47e78bf7530e3ad04987
Autor:
Néstor J. Hernández Lozada, Benke Hong, Joshua C. Wood, Lorenzo Caputi, Jérôme Basquin, Ling Chuang, Maritta Kunert, Carlos E. Rodríguez López, Chloe Langley, Dongyan Zhao, C. Robin Buell, Benjamin R. Lichman, Sarah E. O’Connor
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Iridoid compounds are an important class of natural products. Here, the authors report on the discovery and engineering of nepetalactol-related short chain reductases and their application for the biosynthesis of nepetalactol or nepetalactone stereoi
Externí odkaz:
https://doaj.org/article/25ab1b4b3b3b4dc29163150181a67ada
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Plants produce a wide variety of pharmacologically active molecules classified as natural products. Derivatization of these natural products can modulate or improve the bioactivity of the parent compound. Unfortunately, chemical derivatization of nat
Externí odkaz:
https://doaj.org/article/bc725de3968b46d0bea1863ee08f2663
Autor:
Néstor J. Hernández Lozada, Benke Hong, Joshua C. Wood, Lorenzo Caputi, Jérôme Basquin, Ling Chuang, Maritta Kunert, Carlos E. Rodríguez López, Chloe Langley, Dongyan Zhao, C. Robin Buell, Benjamin R. Lichman, Sarah E. O’Connor
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/c5e7fa52e8da4700ba411104aeca0fc9
Autor:
Katharine Davis, Danai S. Gkotsi, Duncan R. M. Smith, Rebecca J. M. Goss, Lorenzo Caputi, Sarah E. O’Connor
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Plant secondary metabolites have applications for the food, biofuel, and pharmaceutical industries. Recent advances in pathway elucidation and host expression systems now allow metabolic engineering of plant metabolic pathways to produce “new-to-na
Externí odkaz:
https://doaj.org/article/e329153a04ac41bab6b390ffbe57ce64
Autor:
Philipp Stephan, Chloe Langley, Daniela Winkler, Jérôme Basquin, Lorenzo Caputi, Sarah E. O’Connor, Hajo Kries
Publikováno v:
Angewandte Chemie International Edition
Engineering of biosynthetic enzymes is increasingly employed to synthesize structural analogues of antibiotics. Of special interest are non-ribosomal peptide synthetases (NRPSs) responsible for production of important antimicrobial peptides. Here, di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81461b0437bd3d712d12dd31e8320c1
https://hdl.handle.net/21.11116/0000-000D-4CA3-621.11116/0000-000D-4CA5-421.11116/0000-000D-4CA6-3
https://hdl.handle.net/21.11116/0000-000D-4CA3-621.11116/0000-000D-4CA5-421.11116/0000-000D-4CA6-3
Autor:
Benke Hong, Dagny Grzech, Lorenzo Caputi, Prashant Sonawane, Carlos E. Rodríguez López, Mohamed Omar Kamileen, Néstor J. Hernández Lozada, Veit Grabe, Sarah E. O’Connor
Publikováno v:
Nature
Strychnine is a natural product that, through isolation, structural elucidation and synthetic efforts, shaped the field of organic chemistry. Currently, strychnine is used as a pesticide to control rodents1 because of its potent neurotoxicity2,3. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472baa74ab2c504cb2d30d659601c9e3
https://doi.org/10.1038/s41586-022-04950-4
https://doi.org/10.1038/s41586-022-04950-4
Autor:
Chenxin Li, Joshua C. Wood, Anh Hai Vu, John P. Hamilton, Carlos Eduardo Rodriguez Lopez, Richard M. E. Payne, Delia Ayled Serna Guerrero, Klaus Gase, Kotaro Yamamoto, Brieanne Vaillancourt, Lorenzo Caputi, Sarah E. O’Connor, C. Robin Buell
Publikováno v:
Nature Chemical Biology
Advances in omics technologies now permit the generation of highly contiguous genome assemblies, detection of transcripts and metabolites at the level of single cells and high-resolution determination of gene regulatory features. Here, using a comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff82168ca6aba539f9f19ed6d0bf4565
https://hdl.handle.net/21.11116/0000-000D-2BC0-A21.11116/0000-000D-2BBE-E21.11116/0000-000D-2BBF-D21.11116/0000-000D-2BBC-0
https://hdl.handle.net/21.11116/0000-000D-2BC0-A21.11116/0000-000D-2BBE-E21.11116/0000-000D-2BBF-D21.11116/0000-000D-2BBC-0
Autor:
Anna Stavrinides, Evangelos C. Tatsis, Lorenzo Caputi, Emilien Foureau, Clare E. M. Stevenson, David M. Lawson, Vincent Courdavault, Sarah E. O'Connor
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The stereochemistry of the plant heteroyohimbine alkaloids is a key factor determining their diverse biological activities. Here, the authors carry out structural, localization and genetic experiments to understand the mechanism of stereoselectivity
Externí odkaz:
https://doaj.org/article/7fa19d5198334538bd3e87a811316141