Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Lorenza Pecciarini"'
Autor:
Chiara Lazzari, Lorenza Pecciarini, Claudio Doglioni, Federica Pedica, Ana Maria Samanes Gajate, Alessandra Bulotta, Vanesa Gregorc, Maria Giulia Cangi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Rearrangements involving the neurotrophin kinase (NTRK) genes NTRK1, NTRK2 and NTRK3 with different fusion partners have been observed in both adult and pediatric solid tumors. Larotrectinib and entrectinib have been the first tumor-agnostic compound
Externí odkaz:
https://doaj.org/article/6dd38d53ef6947b1a779a3dd317b252d
Autor:
Lorenza Pecciarini, Emanuela Brunetto, Greta Grassini, Valeria De Pascali, Francesca Rita Ogliari, Anna Talarico, Giovanna Marra, Gilda Magliacane, Miriam Redegalli, Gianluigi Arrigoni, Chiara Lazzari, Vanesa Gregorc, Alessandra Bulotta, Claudio Doglioni, Maria Giulia Cangi
Publikováno v:
Cells, Vol 12, Iss 8, p 1135 (2023)
The ability to identify the broadest range of targetable gene fusions is crucial to facilitate personalized therapy selection for advanced lung adenocarcinoma (LuADs) patients harboring targetable receptor tyrosine kinase (RTK) genomic alterations. I
Externí odkaz:
https://doaj.org/article/4404556ae0164aec9fe83f1ca1c4212f
Autor:
Gilda Magliacane, Emanuela Brunetto, Silvia Calzavara, Alice Bergamini, Giovanni Battista Pipitone, Giovanna Marra, Miriam Redegalli, Greta Grassini, Emanuela Rabaiotti, Gianluca Taccagni, Lorenza Pecciarini, Paola Carrera, Giorgia Mangili, Claudio Doglioni, Maria Giulia Cangi
Publikováno v:
Cancers, Vol 15, Iss 1, p 43 (2022)
Assessment of HRD status is now essential for ovarian cancer patient management. A relevant percentage of high-grade serous carcinoma (HGSC) is characterized by HRD, which is caused by genetic alterations in the homologous recombination repair (HRR)
Externí odkaz:
https://doaj.org/article/063dd3f2f30b4f8ea09dbfbb08640206
Autor:
Luciano Cascione, Andrea Rinaldi, Alessio Bruscaggin, Chiara Tarantelli, Alberto J. Arribas, Ivo Kwee, Lorenza Pecciarini, Afua A. Mensah, Valeria Spina, Elaine Y.L. Chung, Lodovico Terzi di Bergamo, Stephan Dirnhofer, Alexandar Tzankov, Roberto N. Miranda, Ken H. Young, Alexandra Traverse-Glehen, Gianluca Gaidano, Steven H. Swerdlow, Randy Gascoyne, Raul Rabadan, Maurilio Ponzoni, Govind Bhagat, Davide Rossi, Emanuele Zucca, Francesco Bertoni
Publikováno v:
Haematologica, Vol 104, Iss 12 (2019)
Externí odkaz:
https://doaj.org/article/0dd09524151d43fca254706ac775bfa2
Autor:
Vanesa Gregorc, Chiara Lazzari, Mario Mandalá, Stefania Ippati, Alessandra Bulotta, Maria Giulia Cangi, Abdelrahman Khater, Maria Grazia Viganò, Aurora Mirabile, Lorenza Pecciarini, Francesca Rita Ogliari, Gianluigi Arrigoni, Greta Grassini, Giulia Veronesi, Claudio Doglioni
Publikováno v:
Cancers, Vol 13, Iss 9, p 2023 (2021)
Tailored therapies based on the identification of molecular targets currently represent a well-established therapeutic scenario in the treatment of non-small cell lung cancer (NSCLC) patients. However, while aiming to improve patients’ response to
Externí odkaz:
https://doaj.org/article/861ea1405fc847078648e98aac5086eb
Autor:
Chiara Lazzari, Alessandra Bulotta, Maria Giulia Cangi, Gabriele Bucci, Lorenza Pecciarini, Silvia Bonfiglio, Vincenza Lorusso, Stefania Ippati, Gianluigi Arrigoni, Greta Grassini, Claudio Doglioni, Vanesa Gregorc
Publikováno v:
Diagnostics, Vol 10, Iss 12, p 1092 (2020)
Lung cancer remains the first cause of cancer-related deaths worldwide. Thanks to the improvement in the knowledge of the biology of non-small cell lung cancer (NSCLC), patients’ survival has significantly improved. A growing number of targetable m
Externí odkaz:
https://doaj.org/article/c81bb2df08d649779ef2b9fbb0aee587
Autor:
Daniela Belloni, Silvia Heltai, Maurilio Ponzoni, Antonello Villa, Barbara Vergani, Lorenza Pecciarini, Magda Marcatti, Stefania Girlanda, Giovanni Tonon, Fabio Ciceri, Federico Caligaris-Cappio, Marina Ferrarini, Elisabetta Ferrero
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Multiple myeloma develops primarily inside the bone marrow microenvironment, that confers pro-survival signals and drug resistance. 3D cultures that reproduce multiple myeloma-bone marrow interactions are needed to fully investigate multiple myeloma
Externí odkaz:
https://doaj.org/article/f41e8388176c48288fb37204a8451d1b
Autor:
Emanuela Brunetto, Anna Maria Ferrara, Francesca Rampoldi, Anna Talarico, Elena DalCin, Greta Grassini, Lorenzo Spagnuolo, Isabella Sassi, Antonella Ferro, Lucia Veronica Cuorvo, Mattia Barbareschi, Sara Piccinin, Roberta Maestro, Lorenza Pecciarini, Claudio Doglioni, Maria Giulia Cangi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 6, Pp 579-590 (2013)
The CDC25A-CDK2 pathway has been proposed as critical for the oncogenic action of human epidermal growth factor receptor 2 (HER2) in mammary epithelial cells. In particular, transgenic expression of CDC25A cooperates with HER2 in promoting mammary tu
Externí odkaz:
https://doaj.org/article/1610277cf34842eebbe1fdd3cdb8d5a3
Autor:
Andreas Agathangelidis, Lydia Scarfò, Federica Barbaglio, Benedetta Apollonio, Maria Teresa Sabrina Bertilaccio, Pamela Ranghetti, Maurilio Ponzoni, Gabriella Leone, Valeria De Pascali, Lorenza Pecciarini, Paolo Ghia, Federico Caligaris-Cappio, Cristina Scielzo
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134748 (2015)
Externí odkaz:
https://doaj.org/article/4e567ea0fb9b4a0eb811aa0e09c2f224
Autor:
Miriam Redegalli, Greta Grassini, Gilda Magliacane, Lorenza Pecciarini, Marco Schiavo Lena, Chanel E. Smart, Rebecca L. Johnston, Nicola Waddell, Roberta Maestro, Marina Macchini, Giulia Orsi, Maria Chiara Petrone, Gemma Rossi, Gianpaolo Balzano, Massimo Falconi, Paolo G. Arcidiacono, Michele Reni, Claudio Doglioni, Maria Giulia Cangi
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease, for which it is crucial to promptly detect actionable and prognostic alterations to drive specific therapeutic decisions, regardless of tumor resectability status. Endoscopic ult