Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lorenza Francescut"'
Autor:
Tanja Steiner, Lorenza Francescut, Simon Byrne, Timothy Hughes, Archana Jayanthi, Irina Guschina, John Harwood, Katherine Cianflone, Cordula Stover, Sheila Francis
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92404 (2014)
Genetic, dietary and immune factors contribute to the pathogenesis of atherosclerosis in humans and mice. Complement activation is an integral part of the innate immune defence but also shapes cellular responses and influences directly triglyceride s
Externí odkaz:
https://doaj.org/article/6e7e2dc8de124d9abcd1e4d12be77a54
Autor:
Bernard Burke, Helen Pearson, Lorenza Francescut, Loems Ziegler-Heitbrock, Karl J. Staples, Marion Frankenberger, Fattah Sotoodehnejadnematalahi
Publikováno v:
Immunobiology. 216:832-839
This study tested the hypothesis that prolonged severe hypoxia during monocyte to macrophage differentiation results in macrophages with a pattern of gene expression and phenotype distinct from those maturing in normal oxygen levels. Macrophages accu
Publikováno v:
Circulation. 132
Introduction: Ion channels contribute significantly to platelet physiology, including control of Ca 2+ as a second messenger. Although there is a clear link between platelet activation and shear stress, no study has examined the functional relevance
Autor:
Peter W. Andrew, Irina Elliott, Nina Ivanovska, Luke Richards, S. Byrne, Wilhelm J. Schwaeble, Petya Dimitrova, Lee Machado, Cordula M. Stover, Hannah Brewin, Fatima Mohamed, Aline Dupont, Aras Kadioglu, Nur'Ain Salehen, Rozita Adib, Lorenza Francescut, Sarah Glenn
Publikováno v:
Medical Microbiology and Immunology
Streptococcus pneumoniae and Listeria monocytogenes, pathogens which can cause severe infectious disease in human, were used to infect properdin-deficient and wildtype mice. The aim was to deduce a role for properdin, positive regulator of the altern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f462e1bb651c8d814137792140eced96
http://nectar.northampton.ac.uk/11034/1/Dupont_Aline_etal_SL_2014_Septicaemia_models_using_Streptococcus_pneumoniae_and_Listeria_monocytogenes_understanding_the_role_of_complement_properdin.pdf
http://nectar.northampton.ac.uk/11034/1/Dupont_Aline_etal_SL_2014_Septicaemia_models_using_Streptococcus_pneumoniae_and_Listeria_monocytogenes_understanding_the_role_of_complement_properdin.pdf
Autor:
S. Byrne, Sheila E. Francis, Tanja Steiner, Lorenza Francescut, Katherine Cianflone, Cordula M. Stover
Atherosclerosis is a chronic progressive inflammatory disease which manifests in the arterial vascular tree. It is a major cause of cardiovascular morbidity and contributes significantly to mortality in the developed world. Triggers for this inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58b11cea9cf3c1d9d7f43c7c402751a
https://europepmc.org/articles/PMC6741550/
https://europepmc.org/articles/PMC6741550/
Publikováno v:
Heart. 97:e7-e7
Background Atherosclerosis in humans and mice has inflammatory, immune and metabolic components. Mice lacking low-density lipoprotein receptor (LDLR(−/−)) may be protected from atherogenesis by some components of the complement system. The serum