Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lorenza Ciani"'
Autor:
Faye McLeod, Alessandro Bossio, Aude Marzo, Lorenza Ciani, Sara Sibilla, Saad Hannan, Gemma A. Wilson, Ernest Palomer, Trevor G. Smart, Alasdair Gibb, Patricia C. Salinas
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1060-1071 (2018)
Summary: The structural and functional plasticity of synapses is critical for learning and memory. Long-term potentiation (LTP) induction promotes spine growth and AMPAR accumulation at excitatory synapses, leading to increased synaptic strength. Glu
Externí odkaz:
https://doaj.org/article/4a86144031c246239e56082deb8a5668
Correction: Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons.
Autor:
Naila Haq, Christoph Schmidt-Hieber, Fernando J Sialana, Lorenza Ciani, Janosch P Heller, Michelle Stewart, Liz Bentley, Sara Wells, Richard J Rodenburg, Patrick M Nolan, Elizabeth Forsythe, Michael C Wu, Gert Lubec, Patricia C Salinas, Michael Häusser, Philip L Beales, Sofia Christou-Savina
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000520 (2019)
[This corrects the article DOI: 10.1371/journal.pbio.3000414.].
Externí odkaz:
https://doaj.org/article/e9e4591deded4a4d8c04f40819a54f18
Autor:
Naila Haq, Christoph Schmidt-Hieber, Fernando J Sialana, Lorenza Ciani, Janosch P Heller, Michelle Stewart, Liz Bentley, Sara Wells, Richard J Rodenburg, Patrick M Nolan, Elizabeth Forsythe, Michael C Wu, Gert Lubec, P Salinas, Michael Häusser, Philip L Beales, Sofia Christou-Savina
Publikováno v:
PLoS Biology, Vol 17, Iss 9, p e3000414 (2019)
Bardet-Biedl syndrome (BBS), a ciliopathy, is a rare genetic condition characterised by retinal degeneration, obesity, kidney failure, and cognitive impairment. In spite of progress made in our general understanding of BBS aetiology, the molecular an
Externí odkaz:
https://doaj.org/article/476db0f2540d4ebfa5d72cbe98ee01fd
Autor:
Patrick M. Nolan, Michael C. Wu, Elizabeth Forsythe, Michael Häusser, Naila Haq, Sonia Christou-Savina, Sara Wells, Liz Bentley, Richard J. Rodenburg, Philip L. Beales, Fernando J. Sialana, Michelle Stewart, Christoph Schmidt-Hieber, Gert Lubec, Lorenza Ciani, Janosch P. Heller
Bardet-Biedl syndrome (BBS), a ciliopathy, is a rare genetic condition characterised by retina degeneration, obesity, kidney failure and cognitive impairment. In spite of a progress made in general understanding of BBS aetiology, the molecular mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5f3ad2fba779f7dec1aeb25b1ef098
Autor:
Gert Lubec, Patricia C. Salinas, Sara Wells, Michael Häusser, Liz Bentley, Naila Haq, Patrick M. Nolan, Christoph Schmidt-Hieber, Lorenza Ciani, Richard J. Rodenburg, Fernando J. Sialana, Michelle Stewart, Elizabeth Forsythe, Philip L. Beales, Janosch P. Heller, Sonia Christou-Savina, Michael C. Wu
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000520 (2019)
[This corrects the article DOI: 10.1371/journal.pbio.3000414.].
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9a4d09ea91bc4197caf151ad267d6d
https://doi.org/10.1371/journal.pbio.3000520
https://doi.org/10.1371/journal.pbio.3000520
Autor:
Aude, Marzo, Soledad, Galli, Douglas, Lopes, Faye, McLeod, Marina, Podpolny, Margarita, Segovia-Roldan, Lorenza, Ciani, Silvia, Purro, Francesca, Cacucci, Alasdair, Gibb, Patricia C, Salinas
Publikováno v:
Current Biology
Summary Synapse degeneration occurs early in neurodegenerative diseases and correlates strongly with cognitive decline in Alzheimer’s disease (AD). The molecular mechanisms that trigger synapse vulnerability and those that promote synapse regenerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37c3606cea34c572f378d9c317e3b45b
https://pubmed.ncbi.nlm.nih.gov/27593374
https://pubmed.ncbi.nlm.nih.gov/27593374
Autor:
Alasdair J. Gibb, Macarena Sahores, Ellen M. Dickins, Douglas M. Lopes, Kieran A. Boyle, Patricia C. Salinas, Derek Anane, Lorenza Ciani
Publikováno v:
Proceedings of the National Academy of Sciences. 108:10732-10737
The balance between excitatory and inhibitory synapses is crucial for normal brain function. Wnt proteins stimulate synapse formation by increasing synaptic assembly. However, it is unclear whether Wnt signaling differentially regulates the formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1c03d439ad332736b6de9cfb840714
https://doi.org/10.1073/pnas.1018132108
https://doi.org/10.1073/pnas.1018132108
Autor:
Monica Hoyos-Flight, Eliza Siomou, Patricia C. Salinas, Lorenza Ciani, Silvia A. Purro, Eleanna Stamatakou
Publikováno v:
The Journal of Neuroscience. 28:8644-8654
Axon guidance and target-derived signals control axonal behavior by regulating the cytoskeleton through poorly defined mechanisms. In particular, how these signaling molecules regulate the growth and directionality of microtubules is not well underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46c0502f1ab98ddd03e7e4f77af2f6b
https://doi.org/10.1523/jneurosci.2320-08.2008
https://doi.org/10.1523/jneurosci.2320-08.2008
Autor:
Lorenza, Ciani, Aude, Marzo, Kieran, Boyle, Eleanna, Stamatakou, Douglas M, Lopes, Derek, Anane, Faye, McLeod, Silvana B, Rosso, Alasdair, Gibb, Patricia C, Salinas
Publikováno v:
Nature Communications
The functional assembly of the synaptic release machinery is well understood; however, how signalling factors modulate this process remains unknown. Recent studies suggest that Wnts play a role in presynaptic function. To examine the mechanisms invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee9c15fa38672615b9aec10c943f7646
https://pubmed.ncbi.nlm.nih.gov/26400647
https://pubmed.ncbi.nlm.nih.gov/26400647
Autor:
Lorenza Ciani, Patricia C. Salinas
Publikováno v:
BMC Cell Biology, Vol 8, Iss 1, p 27 (2007)
BMC Cell Biology
BMC Cell Biology
Background Wnt factors are a large family of signaling molecules that play important roles in the regulation of cell fate specification, tissue polarity and cell movement. In the nervous system, Wnts also regulates the formation of neuronal connectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ef859b80c98d1d5c31117401f9afb9
http://www.biomedcentral.com/1471-2121/8/27
http://www.biomedcentral.com/1471-2121/8/27